Publications by authors named "Jackson Cahn"

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Mechanistic investigation of the formation of fluorinated polycyclic aromatic compounds during the thermal decomposition of polyvinylidene fluoride.
Aaron D Ajeti, Jackson R Cahn, Shubham Vyas

Chemosphere· November 2025

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Chemical richness and diversity of uncultivated 'Entotheonella' symbionts in marine sponges.
Maria Dell, Masato Kogawa, Alena B Streiff, Taro Shiraishi, Alessandro Lotti, Jackson K B Cahn

Nat Chem Biol· November 2025

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CRISPR-Editing of the Vero Cell Line Improves Processability of Live Virus Vaccines by Enabling Targeted Proteolysis of Fibronectin.
Jackson K B Cahn, Henry Ludwicki, Jillian Shingler, Shannon Gulvin, Young Zhang

Biotechnol Bioeng· August 2025

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Dual-Factor-Controlled Dynamic Precursors Enable On-Demand Thermoset Degradation and Recycling.
Zepeng Lei, Zirui Wang, Huan Jiang, Jackson R Cahn, Hongxuan Chen

Adv Mater· November 2024

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Distribution and diversity of 'Tectomicrobia', a deep-branching uncultivated bacterial lineage harboring rich producers of bioactive metabolites.
Eike E Peters, Jackson K B Cahn, Alessandro Lotti, Asimenia Gavriilidou, Ursula A E Steffens

ISME Commun· May 2023

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Cyanurate-Linked Covalent Organic Frameworks Enabled by Dynamic Nucleophilic Aromatic Substitution.
Zepeng Lei, Lacey J Wayment, Jackson R Cahn, Hongxuan Chen, Shaofeng Huang

J Am Chem Soc· October 2022

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Marine Sponge Endosymbionts: Structural and Functional Specificity of the Microbiome within Cells.
Qi Yang, Jackson K B Cahn, Jörn Piel, Yue-Fan Song, Wei Zhang

Microbiol Spectr· June 2022

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Single-cell metabolite detection and genomics reveals uncultivated talented producer.
Masato Kogawa, Rimi Miyaoka, Franziska Hemmerling, Masahiro Ando, Kei Yura, Jackson K B Cahn

PNAS Nexus· March 2022

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Opening up the Single-Cell Toolbox for Microbial Natural Products Research.
Jackson K B Cahn, Jörn Piel

Angew Chem Int Ed Engl· August 2021

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A monodomain class II terpene cyclase assembles complex isoprenoid scaffolds.
Philipp Moosmann, Felix Ecker, Stefan Leopold-Messer, Jackson K B Cahn, Cora L Dieterich

Nat Chem· October 2020

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Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated "Entotheonella" Sponge Symbionts.
Silke Reiter, Jackson K B Cahn, Vincent Wiebach, Reiko Ueoka, Jörn Piel

Chembiochem· February 2020

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The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order.
Douglas H Juers, Christopher A Farley, Christopher P Saxby, Rosemary A Cotter, Jackson K B Cahn

Acta Crystallogr D Struct Biol· September 2018

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Enzyme Nicotinamide Cofactor Specificity Reversal Guided by Automated Structural Analysis and Library Design.
Jackson K B Cahn, Sabine Brinkmann-Chen, Frances H Arnold

Methods Mol Biol· July 2018

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Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble.
Andrew R Buller, Paul van Roye, Jackson K B Cahn, Remkes A Scheele, Michael Herger

J Am Chem Soc· June 2018

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Single-bacterial genomics validates rich and varied specialized metabolism of uncultivated sponge symbionts.
Tetsushi Mori, Jackson K B Cahn, Micheal C Wilson, Roy A Meoded, Vincent Wiebach

Proc Natl Acad Sci U S A· February 2018

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4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation.
Seth A Lieblich, Katharine Y Fang, Jackson K B Cahn, Jeffrey Rawson, Jeanne LeBon

J Am Chem Soc· June 2017

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Directed Evolution of a Bright Near-Infrared Fluorescent Rhodopsin Using a Synthetic Chromophore.
Lukas Herwig, Austin J Rice, Claire N Bedbrook, Ruijie K Zhang, Antti Lignell, Jackson K B Cahn

Cell Chem Biol· March 2017

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A General Tool for Engineering the NAD/NADP Cofactor Preference of Oxidoreductases.
Jackson K B Cahn, Caroline A Werlang, Armin Baumschlager, Sabine Brinkmann-Chen, Stephen L Mayo

ACS Synth Biol· February 2017

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Artificial domain duplication replicates evolutionary history of ketol-acid reductoisomerases.
Jackson K B Cahn, Sabine Brinkmann-Chen, Andrew R Buller, Frances H Arnold

Protein Sci· July 2016

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Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models.
Sheel C Dodani, Gert Kiss, Jackson K B Cahn, Ye Su, Vijay S Pande

Nat Chem· May 2016

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Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases.
Jackson K B Cahn, Sabine Brinkmann-Chen, Thomas Spatzal, Jared A Wiig, Andrew R Buller

Biochem J· June 2015

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Structural, functional, and spectroscopic characterization of the substrate scope of the novel nitrating cytochrome P450 TxtE.
Sheel C Dodani, Jackson K B Cahn, Tillmann Heinisch, Sabine Brinkmann-Chen, John A McIntosh

Chembiochem· October 2014

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General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH.
Sabine Brinkmann-Chen, Tilman Flock, Jackson K B Cahn, Christopher D Snow, Eric M Brustad

Proc Natl Acad Sci U S A· July 2013

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The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Haley Marshall, Murugappan Venkat, Nang San Hti Lar Seng, Jackson Cahn, Douglas H Juers

Acta Crystallogr D Biol Crystallogr· January 2012

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Cell adhesion to borate glasses by colloidal probe microscopy.
Sheldon M Wiederhorn, Young-Hun Chae, Carl G Simon, Jackson Cahn, Yan Deng

Acta Biomater· May 2011

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