Publications by authors named "Jaclyn Mann"

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To end the HIV-1 pandemic, concerted research efforts must focus on sub-Saharan Africa.
Monray E Williams, Jaclyn K Mann, Thumbi Ndung'u, Marius B Tincho, Marcel Tongo

Nat Rev Microbiol· July 2025

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HIV-1 Gag-protease-driven replicative capacity influences T-cell metabolism, cytokine induction, and viral cell-to-cell spread.
Omolara O Baiyegunhi, Kensane Mthembu, Ann-Kathrin Reuschl, Doty Ojwach, Omotayo Farinre, Jaclyn Mann

mBio· April 2025

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Genetic determinants of HIV-1 subtype C Nef-mediated SERINC3 down-regulation.
Nikeisha Samlall, Tarylee Reddy, Nasreen Ismail, Mark A Brockman, Zabrina L Brumme, Jaclyn K Mann

Virol J· April 2025

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No detectable differences in Nef-mediated downregulation of HLA-I and CD4 molecules among HIV-1 group M lineages circulating in Cameroon, where the pandemic originated.
Nelson Sonela, Jaclyn Mann, Celestin Godwe, Oumarou H Goni, Mérime Tchakoute

Front Virol· May 2024

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Hen egg white bovine colostrum supplement reduces symptoms of mild/moderate COVID-19: a randomized control trial.
Jaclyn Kelly Mann, Tarylee Reddy, Mary van der Stok, Ayanda Ngubane, Takalani Mulaudzi

Future Sci OA· September 2023

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Corrigendum to "Partial compartmentalisation of HIV-1 subtype C between lymph nodes, peripheral blood mononuclear cells and plasma" [Virology 582 (2023) 62-70].
Neschika Jeewanraj, Tawanda Mandizvo, Takalani Mulaudzi, Nombali Gumede, Zaza Ndhlovu, Jaclyn Mann

Virology· August 2023

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Generation and characterization of infectious molecular clones of transmitted/founder HIV-1 subtype C viruses.
Bonisile Luthuli, Kamini Gounder, Martin J Deymier, Krista L Dong, Alejandro B Balazs, Jaclyn K Mann

Virology· June 2023

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Differing natural killer cell, T cell and antibody profiles in antiretroviral-naive HIV-1 viraemic controllers with and without protective HLA alleles.
Ana Moyano, Bongiwe Ndlovu, Msizi Mbele, Kewreshini Naidoo, Nasreen Khan, Jaclyn K Mann

PLoS One· June 2023

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Partial compartmentalisation of HIV-1 subtype C between lymph nodes, peripheral blood mononuclear cells and plasma.
Neschika Jeewanraj, Tawanda Mandizvo, Takalani Mulaudzi, Nombali Gumede, Zaza Ndhlovu, Jaclyn Mann

Virology· May 2023

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HIV-1 subtype C Nef-mediated SERINC5 down-regulation significantly contributes to overall Nef activity.
Delon Naicker, Nelson Sonela, Steven W Jin, Takalani Mulaudzi, Doty Ojwach, Jaclyn K Mann

Retrovirology· March 2023

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Subtle Longitudinal Alterations in Env Sequence Potentiate Differences in Sensitivity to Broadly Neutralizing Antibodies following Acute HIV-1 Subtype C Infection.
Tawanda Mandizvo, Nombali Gumede, Bongiwe Ndlovu, Siphiwe Ndlovu, Jaclyn K Mann

J Virol· December 2022

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CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection.
Omolara O Baiyegunhi, Jaclyn Mann, Trevor Khaba, Thandeka Nkosi, Anele Mbatha

Nat Commun· July 2022

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Attenuated HIV-1 Nef But Not Vpu Function in a Cohort of Rwandan Long-Term Survivors.
Gisele Umviligihozo, Jaclyn K Mann, Steven W Jin, Francis M Mwimanzi, Hua-Shiuan A Hsieh

Front Virol· June 2022

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Determinants of natural HIV-1 control.
Ana Moyano, Thumbi Ndung'u, Jaclyn K. Mann

AIDS Rev· April 2022

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Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa.
Omotayo Farinre, Kamini Gounder, Tarylee Reddy, Marcel Tongo, Jonathan Hare, Jaclyn K Mann

Retrovirology· May 2021

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Effects of TNF-α and IL-10-819 T>C single nucleotide polymorphisms on urogenital schistosomiasis in preschool children in Zimbabwe.
Amos Marume, Theresa Chimponda, Arthur Vengesai, Caroline Mushayi, Jaclyn Mann

Afr J Lab Med· April 2021

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Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design.
Doty B A Ojwach, Paradise Madlala, Michelle Gordon, Thumbi Ndung'u, Jaclyn K Mann

Virology· February 2021

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HIV-1 evades a Gag mutation that abrogates killer cell immunoglobulin-like receptor binding and disinhibits natural killer cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype.
Maja C Ziegler, Kewreshini Naidoo, Anais Chapel, Sindiswa Nkotwana, Jaclyn Mann

AIDS· January 2021

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Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5.
Steven W Jin, Francis M Mwimanzi, Jaclyn K Mann, Mwebesa Bosco Bwana, Guinevere Q Lee

PLoS Pathog· September 2020

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Interleukin-10 and tumour necrosis factor alpha promoter region polymorphisms and susceptibility to urogenital schistosomiasis in young Zimbabwean children living in endemic regions.
Amos Marume, Arthur Vengesai, Jaclyn Mann, Takafira Mduluza

S Afr J Infect Dis· September 2020

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Consequences of HLA-associated mutations in HIV-1 subtype C Nef on HLA-I downregulation ability.
Jaclyn K Mann, Erasha Rajkoomar, Steven W Jin, Qiniso Mkhize, Omolara Baiyegunhi

J Med Virol· August 2020

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An HIV-1 Nef genotype that diminishes immune control mediated by protective human leucocyte antigen alleles.
Francis Mwimanzi, Isaac Ngare, Mako Toyoda, Masahiko Mori, Jaclyn Mann

AIDS· July 2020

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Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection.
Daniel M Muema, Ngomu A Akilimali, Okechukwu C Ndumnego, Sipho S Rasehlo, Raveshni Durgiah, Jaclyn K Mann

BMC Med· March 2020

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Modelling and testing of the HIV-1 Nef fitness landscape.
John P Barton, Erasha Rajkoomar, Jaclyn K Mann, Dariusz K Murakowski, Mako Toyoda

Virus Evol· July 2019

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Nef-mediated inhibition of NFAT following TCR stimulation differs between HIV-1 subtypes.
Lisa Naidoo, Zinhle Mzobe, Steven W Jin, Erasha Rajkoomar, Tarylee Reddy, Jaclyn K Mann

Virology· May 2019

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