Publications by authors named "Nasreen Ismail"

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Data-optimal scaling of paired antibody language models.
Mahdi Shafiei Neyestanak, Sarah M Burbach, Karenna Ng, Praneeth Gangavarapu, Jonathan Hurtado, Nasreen Ismail

bioRxiv· November 2025

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Effect of the vaginal live biotherapeutic LACTIN-V (Lactobacillus crispatus CTV-05) on vaginal microbiota and genital tract inflammation among women at high risk of HIV acquisition in South Africa: a phase 2, randomised, placebo-controlled trial.
Anke Hemmerling, Caroline M Mitchell, Suuba Demby, Musie Ghebremichael, Joseph Elsherbini, Nasreen Ismail

Lancet Microbe· June 2025

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Genetic determinants of HIV-1 subtype C Nef-mediated SERINC3 down-regulation.
Nikeisha Samlall, Tarylee Reddy, Nasreen Ismail, Mark A Brockman, Zabrina L Brumme

Virol J· April 2025

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CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection.
Omolara O Baiyegunhi, Jaclyn Mann, Trevor Khaba, Thandeka Nkosi, Anele Mbatha, Nasreen Ismail, Ismail Jajbhay

Nat Commun· July 2022

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Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation.
Seth M Bloom, Nomfuneko A Mafunda, Benjamin M Woolston, Matthew R Hayward, Josephine F Frempong, Nasreen Ismail

Nat Microbiol· March 2022

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Early Initiation of Antiretroviral Therapy Following In Utero HIV Infection Is Associated With Low Viral Reservoirs but Other Factors Determine Viral Rebound.
Jane R Millar, Nomonde Bengu, Vinicius A Vieira, Emily Adland, Julia Roider, Nasreen Ismail

J Infect Dis· December 2021

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Antigen Presenting Cells Contribute to Persistent Immune Activation Despite Antiretroviral Therapy Initiation During Hyperacute HIV-1 Infection.
Kewreshini K Naidoo, Okechukwu C Ndumnego, Nasreen Ismail, Krista L Dong, Thumbi Ndung'u

Front Immunol· December 2021

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Antigen Presenting Cells Link the Female Genital Tract Microbiome to Mucosal Inflammation, With Hormonal Contraception as an Additional Modulator of Inflammatory Signatures.
Elizabeth H Byrne, Mara Farcasanu, Seth M Bloom, Nondumiso Xulu, Jiawu Xu, Nasreen Ismail

Front Cell Infect Microbiol· October 2021

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Correction to: Modeling the temporal dynamics of cervicovaginal microbiota identifies targets that may promote reproductive health.
Alexander Munoz, Matthew R Hayward, Seth M Bloom, Muntsa Rocafort, Sinaye Ngcapu, Nasreen Ismail

Microbiome· October 2021

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Modeling the temporal dynamics of cervicovaginal microbiota identifies targets that may promote reproductive health.
Alexander Munoz, Matthew R Hayward, Seth M Bloom, Muntsa Rocafort, Sinaye Ngcapu, Nasreen Ismail

Microbiome· July 2021

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The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans.
Kewreshini K Naidoo, Zesuliwe B Shangase, Tabassum Rashid, Ayanda Ngubane, Nasreen Ismail

PLoS One· January 2021

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HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE.
Jane R Millar, Nomonde Bengu, Rowena Fillis, Ken Sprenger, Vuyokazi Ntlantsana, Nasreen Ismail

EClinicalMedicine· May 2020

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Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection.
Samuel W Kazer, Toby P Aicher, Daniel M Muema, Shaina L Carroll, Jose Ordovas-Montanes, Nasreen Ismail

Nat Med· April 2020

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Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection.
Daniel M Muema, Ngomu A Akilimali, Okechukwu C Ndumnego, Sipho S Rasehlo, Raveshni Durgiah, Nasreen Ismail

BMC Med· March 2020

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Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants.
Funsho Ogunshola, Gursev Anmole, Rachel L Miller, Emily Goering, Thandeka Nkosi, Nasreen Ismail

Nat Commun· November 2018

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Frequencies of Circulating Th1-Biased T Follicular Helper Cells in Acute HIV-1 Infection Correlate with the Development of HIV-Specific Antibody Responses and Lower Set Point Viral Load.
Omolara Baiyegunhi, Bongiwe Ndlovu, Funsho Ogunshola, Nasreen Ismail, Bruce D Walker

J Virol· August 2018

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Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study.
Krista L Dong, Amber Moodley, Douglas S Kwon, Musie S Ghebremichael, Mary Dong, Nasreen Ismail

Lancet HIV· January 2018

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Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies.
Jenniffer M Mabuka, Anne-Sophie Dugast, Daniel M Muema, Tarylee Reddy, Yathisha Ramlakhan, Nasreen Ismail

Front Immunol· September 2017

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HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer Gag-Specific CD4 T Cells in Chronic Clade C HIV-1 Infection.
Faatima Laher, Srinika Ranasinghe, Filippos Porichis, Nikoshia Mewalal, Karyn Pretorius, Nasreen Ismail

J Virol· April 2017

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Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women.
Christina Gosmann, Melis N Anahtar, Scott A Handley, Mara Farcasanu, Galeb Abu-Ali, Nasreen Ismail

Immunity· January 2017

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CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles.
Catherine K Koofhethile, Zaza M Ndhlovu, Christina Thobakgale-Tshabalala, Julia G Prado, Nasreen Ismail

J Virol· August 2016

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Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study.
Elizabeth H Byrne, Melis N Anahtar, Kathleen E Cohen, Amber Moodley, Nikita Padavattan, Nasreen Ismail

Lancet Infect Dis· April 2016

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Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point.
Zaza M Ndhlovu, Philomena Kamya, Nikoshia Mewalal, Henrik N Kløverpris, Thandeka Nkosi, Nasreen Ismail

Immunity· September 2015

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Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract.
Melis N Anahtar, Elizabeth H Byrne, Kathleen E Doherty, Brittany A Bowman, Hidemi S Yamamoto, Nasreen Ismail

Immunity· May 2015

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HIV control through a single nucleotide on the HLA-B locus.
Henrik N Kløverpris, Mikkel Harndahl, Alasdair J Leslie, Jonathan M Carlson, Nasreen Ismail

J Virol· November 2012

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