Publications by authors named "Jaclyn Patterson"

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Meaning and Joy at Work and Nurse Self-Care Practices: An Exploratory Study.
Amy Glasofer, Raelle Carlino-Filippone, Kimberly O'Malley, Helen-Ann Brown Epstein, Gina Galosi, Jaclyn Patterson

Holist Nurs Pract· October 2025

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Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement.
Linda S Barton, James F Callahan, Juan Cantizani, Nestor O Concha, Ignacio Cotillo Torrejon, Jaclyn R Patterson

Bioorg Med Chem· February 2024

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Using predictive validity to compare associations between brain damage and behavior.
John F Magnotti, Jaclyn S Patterson, Tatiana T Schnur

Hum Brain Mapp· September 2023

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Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf.
Jaclyn R Patterson, Alan P Graves, Patrick Stoy, Mui Cheung, Tina A Desai

J Med Chem· November 2021

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Identification of a Human Whole Blood-Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo.
Xiaoping Xu, Navin Goyal, Melissa H Costell, Theresa Roethke, Christian H James, Jaclyn Patterson

J Pharmacol Exp Ther· March 2021

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Design and Optimization of an Acyclic Amine Series of TRPV4 Antagonists by Electronic Modulation of Hydrogen Bond Interactions.
Jaclyn R Patterson, Lamont R Terrell, Carla A Donatelli, Dennis A Holt, Larry J Jolivette

J Med Chem· December 2020

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Discovery of GSK3527497: A Candidate for the Inhibition of Transient Receptor Potential Vanilloid-4 (TRPV4).
Carl A Brooks, Linda S Barton, David J Behm, Edward J Brnardic, Melissa H Costell, Jaclyn R Patterson

J Med Chem· October 2019

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Discovery of GSK2798745: A Clinical Candidate for Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4).
Carl A Brooks, Linda S Barton, David J Behm, Hilary S Eidam, Ryan M Fox, Jaclyn R Patterson

ACS Med Chem Lett· August 2019

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A randomized clinical trial to evaluate the single-dose pharmacokinetics, pharmacodynamics, and safety of sitagliptin in pediatric patients with type 2 diabetes.
Iain P Fraser, Naomi D Neufeld, Larry A Fox, Mark S Kipnes, Tracie L Miller, Jaclyn K Patterson

Pediatr Diabetes· February 2019

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Optimizing the Use of Electronic Data Sources in Clinical Trials: The Landscape, Part 1.
Ed Kellar, Susan M Bornstein, Aleny Caban, Catherine Célingant, Michelle Crouthamel, Jaclyn K Patterson

Ther Innov Regul Sci· November 2016

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Reply to Lawson et al.: A synergistic approach to mental health research.
Ari Rosenberg, Jaclyn Sky Patterson, Dora E Angelaki

Proc Natl Acad Sci U S A· September 2015

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A computational perspective on autism.
Ari Rosenberg, Jaclyn Sky Patterson, Dora E Angelaki

Proc Natl Acad Sci U S A· July 2015

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Improving the developability profile of pyrrolidine progesterone receptor partial agonists.
Lara S Kallander, David G Washburn, Tram H Hoang, James S Frazee, Patrick Stoy, Jaclyn R Patterson

Bioorg Med Chem Lett· January 2010

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Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects.
Brett Lauring, Victor Dishy, Wen-Lin Luo, Omar Laterza, Jaclyn Patterson

J Clin Pharmacol· December 2009

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A single supratherapeutic dose of vorinostat does not prolong the QTc interval in patients with advanced cancer.
Pamela N Munster, Eric H Rubin, Simon Van Belle, Evan Friedman, Jaclyn K Patterson

Clin Cancer Res· November 2009

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Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors.
Marlys Hammond, David G Washburn, H Tram Hoang, Sharada Manns, James S Frazee, Jaclyn R Patterson

Bioorg Med Chem Lett· August 2009

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Synthesis and SAR of amino acid-derived heterocyclic progesterone receptor full and partial agonists.
Marlys Hammond, Jaclyn R Patterson, Sharada Manns, Tram H Hoang, David G Washburn

Bioorg Med Chem Lett· May 2009

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Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.
Andrea B Sherk, Daniel E Frigo, Christine G Schnackenberg, Jeffrey D Bray, Nicholas J Laping, Jaclyn R Patterson

Cancer Res· September 2008

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Investigation into the structure-activity relationship of novel concentration dependent, dual action T-type calcium channel agonists/antagonists.
William F McCalmont, Jaclyn R Patterson, Michael A Lindenmuth, Tiffany N Heady, Doris M Haverstick

Bioorg Med Chem· June 2005

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Design, synthesis, and biological evaluation of novel T-Type calcium channel antagonists.
William F McCalmont, Tiffany N Heady, Jaclyn R Patterson, Michael A Lindenmuth, Doris M Haverstick

Bioorg Med Chem Lett· July 2004

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