Publications by authors named "Jacob Degner"

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Population Pharmacokinetics of Elagolix in Combination with Low-Dose Estradiol/Norethindrone Acetate in Women with Uterine Fibroids.
Denise Beck, Insa Winzenborg, Mohan Liu, Jacob Degner, Nael M Mostafa

Clin Pharmacokinet· April 2022

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Estimating colocalization probability from limited summary statistics.
Emily A King, Fengjiao Dunbar, Justin Wade Davis, Jacob F Degner

BMC Bioinformatics· May 2021

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Lineage-Resolved Enhancer and Promoter Usage during a Time Course of Embryogenesis.
James P Reddington, David A Garfield, Olga M Sigalova, Aslihan Karabacak Calviello, Raquel Marco-Ferreres, Jacob F Degner

Dev Cell· December 2020

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A Genetic Variant in the BCL2 Gene Associates with Adalimumab Response in Hidradenitis Suppurativa Clinical Trials and Regulates Expression of BCL2.
Mohan Liu, Jacob Degner, Robert W Georgantas, Ahmed Nader, Nael M Mostafa

J Invest Dermatol· March 2020

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Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval.
Emily A King, J Wade Davis, Jacob F Degner

PLoS Genet· December 2019

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Population Pharmacokinetics of Elagolix in Healthy Women and Women with Endometriosis.
Insa Winzenborg, Ahmed Nader, Akshanth R Polepally, Mohan Liu, Jacob Degner

Clin Pharmacokinet· October 2018

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Identification of HLA-DRB1 association to adalimumab immunogenicity.
Mohan Liu, Jacob Degner, Justin Wade Davis, Kenneth B Idler, Ahmed Nader

PLoS One· July 2018

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Promoter shape varies across populations and affects promoter evolution and expression noise.
Ignacio E Schor, Jacob F Degner, Dermot Harnett, Enrico Cannavò, Francesco P Casale

Nat Genet· April 2017

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Genetic variants regulating expression levels and isoform diversity during embryogenesis.
Enrico Cannavò, Nils Koelling, Dermot Harnett, David Garfield, Francesco P Casale, Jacob F Degner

Nature· January 2017

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Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.
Nicholas E Banovich, Xun Lan, Graham McVicker, Bryce van de Geijn, Jacob F Degner

PLoS Genet· September 2014

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Identification of genetic variants that affect histone modifications in human cells.
Graham McVicker, Bryce van de Geijn, Jacob F Degner, Carolyn E Cain, Nicholas E Banovich

Science· November 2013

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The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels.
Athma A Pai, Carolyn E Cain, Orna Mizrahi-Man, Sherryl De Leon, Noah Lewellen, Jacob F Degner

PLoS Genet· March 2013

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DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines.
Jordana T Bell, Athma A Pai, Joseph K Pickrell, Daniel J Gaffney, Roger Pique-Regi, Jacob F Degner

Genome Biol· February 2012

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DNase I sensitivity QTLs are a major determinant of human expression variation.
Jacob F Degner, Athma A Pai, Roger Pique-Regi, Jean-Baptiste Veyrieras, Daniel J Gaffney

Nature· February 2012

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Dissecting the regulatory architecture of gene expression QTLs.
Daniel J Gaffney, Jean-Baptiste Veyrieras, Jacob F Degner, Roger Pique-Regi, Athma A Pai

Genome Biol· January 2012

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Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data.
Roger Pique-Regi, Jacob F Degner, Athma A Pai, Daniel J Gaffney, Yoav Gilad

Genome Res· March 2011

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Fat frogs, mobile genes: unexpected phylogeographic patterns for the ornate chorus frog (Pseudacris ornata).
Jacob F Degner, Diana M Silva, Tyler D Hether, Juan M Daza, Eric A Hoffman

Mol Ecol· June 2010

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Understanding mechanisms underlying human gene expression variation with RNA sequencing.
Joseph K Pickrell, John C Marioni, Athma A Pai, Jacob F Degner, Barbara E Engelhardt

Nature· April 2010

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Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data.
Jacob F Degner, John C Marioni, Athma A Pai, Joseph K Pickrell, Everlyne Nkadori

Bioinformatics· December 2009

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Eight novel tetranucleotide and five cross-species dinucleotide microsatellite loci for the ornate chorus frog (Pseudacris ornata).
Jacob F Degner, Tyler D Hether, Eric A Hoffman

Mol Ecol Resour· March 2009

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