Publications by authors named "Jacob Falck"

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CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination.
Jacob Falck, Josep V Forment, Julia Coates, Martin Mistrik, Jiri Lukas

EMBO Rep· June 2012

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Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities.
Kasper Fugger, Martin Mistrik, Jannie Rendtlew Danielsen, Christoffel Dinant, Jacob Falck

J Cell Biol· September 2009

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HCLK2 is required for activity of the DNA damage response kinase ATR.
Jannie M Rendtlew Danielsen, Dorthe Helena Larsen, Kenneth Bødtker Schou, Raimundo Freire, Jacob Falck

J Biol Chem· February 2009

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Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin.
Fredrik Melander, Simon Bekker-Jensen, Jacob Falck, Jiri Bartek, Niels Mailand

J Cell Biol· April 2008

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks.
Ali Jazayeri, Jacob Falck, Claudia Lukas, Jiri Bartek, Graeme C M Smith

Nat Cell Biol· January 2006

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.
Jacob Falck, Julia Coates, Stephen P Jackson

Nature· March 2005

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Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathway.
Jeppe Agner, Jacob Falck, Jiri Lukas, Jiri Bartek

Exp Cell Res· January 2005

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Alternative splicing and mutation status of CHEK2 in stage III breast cancer.
Vidar Staalesen, Jacob Falck, Stephanie Geisler, Jirina Bartkova, Anne-Lise Børresen-Dale

Oncogene· November 2004

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CHEK2 variant I157T may be associated with increased breast cancer risk.
Outi Kilpivaara, Pia Vahteristo, Jacob Falck, Kirsi Syrjäkoski, Hannaleena Eerola

Int J Cancer· September 2004

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Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention.
Claudia Lukas, Fredrik Melander, Manuel Stucki, Jacob Falck, Simon Bekker-Jensen

EMBO J· July 2004

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Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation.
Zuzana Horejsí, Jacob Falck, Christopher J Bakkenist, Michael B Kastan, Jiri Lukas

Oncogene· April 2004

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Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.
Magtouf Gatei, Katie Sloper, Claus Sorensen, Randi Syljuäsen, Jacob Falck

J Biol Chem· April 2003

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Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage.
Claudia Lukas, Jacob Falck, Jirina Bartkova, Jiri Bartek, Jiri Lukas

Nat Cell Biol· March 2003

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Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.
Claus Storgaard Sørensen, Randi G Syljuåsen, Jacob Falck, Tine Schroeder, Lars Rönnstrand

Cancer Cell· March 2003

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MDC1 is required for the intra-S-phase DNA damage checkpoint.
Michal Goldberg, Manuel Stucki, Jacob Falck, Damien D'Amours, Dinah Rahman

Nature· February 2003

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The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways.
Jacob Falck, John H J Petrini, Bret R Williams, Jiri Lukas, Jiri Bartek

Nat Genet· March 2002

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