Publications by authors named "Jacob Jelsing"

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Hepatoprotective effects of the long-acting fibroblast growth factor 21 analog PF-05231023 in the GAN diet-induced obese and biopsy-confirmed mouse model of nonalcoholic steatohepatitis.
Malte Hasle Nielsen, Matthew P Gillum, Niels Vrang, Jacob Jelsing, Henrik H Hansen

Am J Physiol Gastrointest Liver Physiol· May 2023

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A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity.
Christoffer A Hagemann, Christian Legart, Mathias B Møllerhøj, Martin R Madsen, Henrik H Hansen, Jacob Jelsing

PLoS One· October 2022

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Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH.
Mathias B Møllerhøj, Sanne S Veidal, Kirstine Tølbøl Thrane, Denise Oró, Agnete Overgaard, Jacob Jelsing

Clin Transl Sci· May 2022

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Lipidated PrRP31 metabolites are long acting dual GPR10 and NPFF2 receptor agonists with potent body weight lowering effect.
Flora Alexopoulou, Esben Matzen Bech, Søren Ljungberg Pedersen, Ditte Dencker Thorbek, Ulrike Leurs, Jacob Jelsing

Sci Rep· February 2022

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Integrative transcriptomic profiling of a mouse model of hypertension-accelerated diabetic kidney disease.
Frederikke E Sembach, Helene M Ægidius, Lisbeth N Fink, Thomas Secher, Annemarie Aarup, Jacob Jelsing

Dis Model Mech· October 2021

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Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease.
Mette V Østergaard, Thomas Secher, Michael Christensen, Casper Gravesen Salinas, Urmas Roostalu, Jacob Jelsing

Am J Physiol Renal Physiol· August 2021

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An Optimized Mouse Brain Atlas for Automated Mapping and Quantification of Neuronal Activity Using iDISCO+ and Light Sheet Fluorescence Microscopy.
Johanna Perens, Casper Gravesen Salinas, Jacob Lercke Skytte, Urmas Roostalu, Anders Bjorholm Dahl, Jacob Jelsing

Neuroinformatics· July 2021

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Whole-brain activation signatures of weight-lowering drugs.
Henrik H Hansen, Johanna Perens, Urmas Roostalu, Jacob Lercke Skytte, Casper Gravesen Salinas, Jacob Jelsing

Mol Metab· May 2021

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Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice.
Henrik H Hansen, Rikke V Grønlund, Tamara Baader-Pagler, Peter Haebel, Harald Tammen, Jacob Jelsing

Sci Rep· April 2021

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Whole-brain mapping of amylin-induced neuronal activity in receptor activity-modifying protein 1/3 knockout mice.
Grethe Skovbjerg, Urmas Roostalu, Henrik H Hansen, Thomas A Lutz, Christelle Le Foll, Jacob Jelsing

Eur J Neurosci· April 2021

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Effect of captopril on post-infarction remodelling visualized by light sheet microscopy and echocardiography.
Urmas Roostalu, Louise Thisted, Jacob Lercke Skytte, Casper Gravesen Salinas, Philip Juhl Pedersen, Jacob Jelsing

Sci Rep· March 2021

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Transcriptomic changes in pancreatic islets, adipose and liver after Roux-en-Y gastric bypass in a diet-induced obese rat model.
Chen Zhang, Lise Christine Biehl Rudkjær, Marisa Fernández Cachón, Mechthilde Falkenhahn, Stefan Theis, Jacob Jelsing

Peptides· February 2021

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Rodent models of diabetic kidney disease: human translatability and preclinical validity.
Frederikke E Sembach, Mette V Østergaard, Niels Vrang, Bo Feldt-Rasmussen, Keld Fosgerau, Jacob Jelsing

Drug Discov Today· January 2021

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Identification and Metabolic Profiling of a Novel Human Gut-derived LEAP2 Fragment.
Christoffer A Hagemann, Chen Zhang, Henrik H Hansen, Tina Jorsal, Kristoffer T G Rigbolt, Jacob Jelsing

J Clin Endocrinol Metab· January 2021

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Characterization of local gut microbiome and intestinal transcriptome responses to rosiglitazone treatment in diabetic db/db mice.
Mette Simone Aae Madsen, Rikke Veggerby Grønlund, John Eid, Mikkel Christensen-Dalsgaard, Morten Sommer, Jacob Jelsing

Biomed Pharmacother· January 2021

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3D quantification of changes in pancreatic islets in mouse models of diabetes type I and II.
Urmas Roostalu, Jacob Lercke Skytte, Casper Gravesen Salinas, Thomas Klein, Niels Vrang, Jacob Jelsing

Dis Model Mech· December 2020

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Gut Mucosal Gene Expression and Metabolic Changes After Roux-en-Y Gastric Bypass Surgery.
Tina Jorsal, Marie M Christensen, Brynjulf Mortensen, Eva B Nygaard, Chen Zhang, Jacob Jelsing

Obesity (Silver Spring)· November 2020

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Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy.
Louise Thisted, Mette V Østergaard, Annemarie A Pedersen, Philip J Pedersen, Ross T Lindsay, Jacob Jelsing

Sci Rep· September 2020

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Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis.
Henrik H Hansen, Helene M Ægidius, Denise Oró, Simon S Evers, Sara Heebøll, Jacob Jelsing

BMC Gastroenterol· July 2020

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Automated Image Analyses of Glomerular Hypertrophy in a Mouse Model of Diabetic Nephropathy.
Mette V Østergaard, Frederikke E Sembach, Jacob L Skytte, Urmas Roostalu, Thomas Secher, Jacob Jelsing

Kidney360· June 2020

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The dorsomedial hypothalamus and nucleus of the solitary tract as key regulators in a rat model of chronic obesity.
Chen Zhang, Pernille Barkholt, Jens Christian Nielsen, Ditte Dencker Thorbek, Kristoffer Rigbolt, Jacob Jelsing

Brain Res· January 2020

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Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis.
Helene M Ægidius, Sanne S Veidal, Michael Feigh, Philip Hallenborg, Michele Puglia, Jacob Jelsing

Sci Rep· January 2020

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Impact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice.
Frederikke E Sembach, Lisbeth N Fink, Thea Johansen, Brandon B Boland, Thomas Secher, Jacob Jelsing

Physiol Rep· December 2019

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Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH.
Maria Nicoline Baandrup Kristiansen, Sanne Skovgård Veidal, Christina Christoffersen, Michael Feigh, Niels Vrang, Jacob Jelsing

BMC Gastroenterol· December 2019

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Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease.
Urmas Roostalu, Casper B G Salinas, Ditte D Thorbek, Jacob L Skytte, Katrine Fabricius, Jacob Jelsing

Dis Model Mech· November 2019

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