Publications by authors named "Jacob Kalbfleisch"

Claim this Profile
F
Further Optimization of the mGlu PAM VU6024578/BI02982816: Discovery and Characterization of VU6033685.
Carson W Reed, Jacob F Kalbfleisch, Jeremy A Turkett, Trevor A Trombley, Paul K Spearing

ACS Chem Neurosci· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of VU6024578/BI02982816: An mGlu Positive Allosteric Modulator with Efficacy in Preclinical Antipsychotic and Cognition Models.
Carson W Reed, Jacob F Kalbfleisch, Jeremy A Turkett, Trevor A Trombley, Anthony F Nastase

J Med Chem· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Protease-Activated Receptor 4 (PAR4)-Tethered Ligand Antagonists Using Ultralarge Virtual Screening.
Shannon T Smith, Jackson B Cassada, Lukas Von Bredow, Kevin Erreger, Emma M Webb, Jacob J Kalbfleisch

ACS Pharmacol Transl Sci· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Persistent challenges in the development of an mGlu PAM in vivo tool compound: The discovery of VU6046980.
Jacob J Kalbfleisch, Alice L Rodriguez, Xia Lei, Kelly Weiss, Annie L Blobaum

Bioorg Med Chem Lett· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development and profiling of mGlu NAMs with a range of saturable inhibition of agonist responses in vitro.
Carson W Reed, Alice L Rodriguez, Jacob J Kalbfleisch, Mabel Seto, Matthew T Jenkins

Bioorg Med Chem Lett· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Differential activity of mGlu allosteric modulators provides evidence for mGlu heterodimers at hippocampal Schaffer collateral-CA1 synapses.
Xin Lin, Nicole M Fisher, Shalini Dogra, Rebecca K Senter, Carson W Reed, Jacob J Kalbfleisch

J Biol Chem· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and SAR of a series of mGlu NAMs based on an ethyl-8-methoxy-4-(4-phenylpiperazin-1-yl)quinoline carboxylate core.
Jacob J Kalbfleisch, Carson W Reed, Charlotte Park, Paul K Spearing, Marc C Quitalig

Bioorg Med Chem Lett· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of VU6027459: A First-in-Class Selective and CNS Penetrant mGlu Positive Allosteric Modulator Tool Compound.
Carson W Reed, Jacob J Kalbfleisch, Madison J Wong, Jordan P Washecheck, Ashton Hunter

ACS Med Chem Lett· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M Positive Allosteric Modulators.
Julie L Engers, Aaron M Bender, Jacob J Kalbfleisch, Hyekyung P Cho, Kaelyn S Lingenfelter

ACS Chem Neurosci· March 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Aqueous Photolysis of Benzobicyclon Hydrolysate.
Katryn L Williams, Richie Kaur, Alexander S McFall, Jacob Kalbfleisch, Joshua J Gladfelder

J Agric Food Chem· June 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis