Publications by authors named "Jacob Luber"

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PD-1 regulates tumor-infiltrating CD8+ T cells in both a cell-intrinsic and a cell-extrinsic fashion.
Kristen E Pauken, Samuel C Markson, Thomas S Conway, Vikram R Juneja, Osmaan Shahid, Jacob M Luber

J Exp Med· October 2025

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Machine Learning-Driven Prediction of Spatiotemporal Dynamics of Active Nuclei During Embryogenesis.
Parisa Boodaghi Malidarreh, Priyanshi Borad, Biraaj Rout, Anna Makridou, Shiva Abbasi, Jacob M Luber

Int J Mol Sci· October 2025

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Single-cell RNA-seq reveals disease-specific CD8+ T cell clonal expansion and a high frequency of transcriptionally distinct double-negative T cells in diabetic NOD mice.
Md Zohorul Islam, Sam Zimmerman, Alexis Lindahl, Jon Weidanz, Jose Ordovas-Montanes, Jacob Luber

PLoS One· May 2025

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Su(H) Modulates Enhancer Transcriptional Bursting in Prelude to Gastrulation.
Kelli D Fenelon, Priyanshi Borad, Biraaj Rout, Parisa Boodaghi Malidarreh, Mohammad Sadegh Nasr, Jacob M Luber

Cells· October 2024

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Generalizability of PGS for breast cancer risk in a Los Angeles biobank.
Helen Shang, Yi Ding, Vidhya Venkateswaran, Kristin Boulier, Nikhita Kathuria-Prakash, Jacob M Luber

HGG Adv· July 2024

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BetaBuddy: An automated end-to-end computer vision pipeline for analysis of calcium fluorescence dynamics in β-cells.
Anne M Alsup, Kelli Fowlds, Michael Cho, Jacob M Luber

PLoS One· March 2024

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scRNA-seq Reveals Novel Genetic Pathways and Sex Chromosome Regulation in Tribolium Spermatogenesis.
Michael Robben, Balan Ramesh, Shana Pau, Demetra Meletis, Jacob Luber

Genome Biol Evol· March 2024

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Comparison of the Strengths and Weaknesses of Machine Learning Algorithms and Feature Selection on KEGG Database Microbial Gene Pathway Annotation and Its Effects on Reconstructed Network Topology.
Michael Robben, Mohammad Sadegh Nasr, Avishek Das, Jai Prakash Veerla, Manfred Huber, Jacob Luber

J Comput Biol· July 2023

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BetaBuddy: An end-to-end computer vision pipeline for the automated analysis of insulin secreting β-cells.
Anne M Alsup, Kelli Fowlds, Michael Cho, Jacob M Luber

bioRxiv· April 2023

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Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment.
Kristen E Pauken, Osmaan Shahid, Kaitlyn A Lagattuta, Kelly M Mahuron, Jacob M Luber

J Exp Med· April 2021

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Layilin augments integrin activation to promote antitumor immunity.
Kelly M Mahuron, Joshua M Moreau, Jeff E Glasgow, Devi P Boda, Mariela L Pauli, Jacob M Luber

J Exp Med· September 2020

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A systematic machine learning and data type comparison yields metagenomic predictors of infant age, sex, breastfeeding, antibiotic usage, country of origin, and delivery type.
Alan Le Goallec, Braden T Tierney, Jacob M Luber, Evan M Cofer, Aleksandar D Kostic

PLoS Comput Biol· May 2020

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The Landscape of Genetic Content in the Gut and Oral Human Microbiome.
Braden T Tierney, Zhen Yang, Jacob M Luber, Marc Beaudin, Marsha C Wibowo

Cell Host Microbe· August 2019

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A perfect storm: Genetics and anticommensal antibodies shore up type 1 diabetes.
Jacob M Luber, Aleksandar D Kostic

Sci Immunol· February 2019

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HiGlass: web-based visual exploration and analysis of genome interaction maps.
Peter Kerpedjiev, Nezar Abdennur, Fritz Lekschas, Chuck McCallum, Kasper Dinkla, Jacob M Luber

Genome Biol· August 2018

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Aether: leveraging linear programming for optimal cloud computing in genomics.
Jacob M Luber, Braden T Tierney, Evan M Cofer, Chirag J Patel, Aleksandar D Kostic

Bioinformatics· May 2018

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Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing.
Chao Fang, Huanzi Zhong, Yuxiang Lin, Bing Chen, Mo Han, Jacob M Luber

Gigascience· March 2018

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Gut Microbiota: Small Molecules Modulate Host Cellular Functions.
Jacob M Luber, Aleksandar D Kostic

Curr Biol· April 2017

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