Publications by authors named "Jacques Neefjes"

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Determining Preclinical Safety of Aclarubicin in Pediatric Malignancies.
Darleen S Tu, Aaron K Olson, Kimberly S Waggie, Nicolas M Garcia, Virginia J Hoglund, Jacques Neefjes

Pediatr Blood Cancer· November 2025

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Manipulating anthracyclines for deeper tissue penetration and implications for glycolytic tissues.
Erik R Abels, Esther Ter Linden, Jos H T Rohling, Lennard M Voortman, Lennert Janssen, Jacques Neefjes

Proc Natl Acad Sci U S A· September 2025

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Metabolomic Profiles of Oral Rinse Samples to Distinguish Severe Periodontitis Patients From Non-Periodontitis Controls.
Madeline X F Kosho, Alessio Ciurli, Martin Giera, Jacques Neefjes, Bruno G Loos

J Periodontal Res· August 2025

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Absence of lipopolysaccharide (LPS) expression in breast cancer cells.
Noel F C C de Miranda, Vincent T H B M Smit, Manon van der Ploeg, Jelle Wesseling, Jacques Neefjes

Cell Oncol (Dordr)· August 2025

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Emerging roles of lipid transfer protein dimerization.
Shalom Borst Pauwels, Jacques Neefjes, Birol Cabukusta

J Cell Sci· August 2025

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Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement.
Erika A K Fletcher, Robert A Cordfunke, Aikaterini Nasi, Gunilla Törnqvist, Rob R P M Valentijn, Jacques J Neefjes

Mol Ther Oncol· June 2025

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Engine breakdown of lysosomes and related organelles and the resulting physiology.
Nina Bakker, Marlieke L M Jongsma, Jacques Neefjes

Front Cell Dev Biol· June 2025

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Salmonella, the insidious contributor to gallbladder and colon cancers.
Virginie Stévenin, Jacques Neefjes

Nat Rev Cancer· May 2025

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Determining preclinical safety of Aclarubicin in pediatric malignancies.
Darleen S Tu, Aaron K Olson, Kimberly S Waggie, Nicolas M Garcia, Virginia J Hoglund, Jacques Neefjes

bioRxiv· May 2025

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The Impact of Chemotherapy and Body Mass Index on Cancer-Related Fatigue in Colon Cancer Patients: A PROFILES-Registry Study.
Anneke Kastelein, Floortje Mols, Laura Kervezee, Niels H Chavannes, Hans Gelderblom, Jacques Neefjes

Cancer Med· January 2025

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Anthracyclines disaggregate and restore mutant p63 function: a potential therapeutic approach for AEC syndrome.
Fabiana Boncimino, Ludovica D'Auria, Kristina Todorova, Sabina Y van der Zanden, Jacques Neefjes

Cell Death Discov· January 2025

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Multi-omics analyses of cancer-linked clinical salmonellae reveal bacterial-induced host metabolic shift and mTOR-dependent cell transformation.
Virginie Stévenin, Claudia E Coipan, Janneke W Duijster, Daphne M van Elsland, Linda Voogd, Andra Neefjes-Borst, Jacques Neefjes

Cell Rep· November 2024

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Systems mapping of bidirectional endosomal transport through the crowded cell.
Marlieke L M Jongsma, Nina Bakker, Lenard M Voortman, Roman I Koning, Erik Bos, Jacques Neefjes

Curr Biol· October 2024

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Epstein-Barr virus nuclear antigen EBNA3A modulates IRF3-dependent IFNβ expression.
Sanne L Landman, Maaike E Ressing, Anna M Gram, Rayman T N Tjokrodirijo, Peter A van Veelen, Jacques Neefjes

J Biol Chem· September 2024

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Chromatin as an old and new anticancer target.
Jacques Neefjes, Katerina Gurova, Jay Sarthy, Gábor Szabó, Steven Henikoff

Trends Cancer· August 2024

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Novel -Dimethyl-idarubicin Analogues Are Effective Cytotoxic Agents for ABCB1-Overexpressing, Doxorubicin-Resistant Cells.
Merle A van Gelder, Yufeng Li, Dennis P A Wander, Ilana Berlin, Hermen S Overkleeft, Jacques J C Neefjes

J Med Chem· August 2024

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The ORP9-ORP11 dimer promotes sphingomyelin synthesis.
Birol Cabukusta, Shalom Borst Pauwels, Jimmy J L L Akkermans, Niek Blomberg, Aat A Mulder, Jacques Neefjes

Elife· August 2024

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Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients.
Xiaohang Qiao, Sabina Y van der Zanden, Xiaoyang Li, Minkang Tan, Yunxiang Zhang, Jacques Neefjes

Mol Cancer· June 2024

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Overcoming Barriers in Glioblastoma-Advances in Drug Delivery Strategies.
Esther Ter Linden, Erik R Abels, Thomas S van Solinge, Jacques Neefjes, Marike L D Broekman

Cells· June 2024

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CRISPR-Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition.
Tom A W Schoufour, Anneloes van der Plas-van Duijn, Ian Derksen, Marije Melgers, Jacqueline M F van Veenendaal, Jacques Neefjes

iScience· June 2024

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Monitoring Anthracycline Cancer Drug-Nucleosome Interaction by NMR Using a Specific Isotope Labeling Approach for Nucleosomal DNA.
Clara L van Emmerik, Vincenzo Lobbia, Jacques Neefjes, Frank H T Nelissen, Hugo van Ingen

Chembiochem· May 2024

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A safety screening platform for individualized cardiotoxicity assessment.
Verena Schwach, Rolf H Slaats, Carla Cofiño-Fabres, Simone A Ten Den, José M Rivera-Arbeláez, Jacques Neefjes

iScience· March 2024

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Balanced Epigenetic Regulation of MHC Class I Expression in Tumor Cells by the Histone Ubiquitin Modifiers BAP1 and PCGF1.
Ruud H Wijdeven, Sietse J Luk, Tom A W Schoufour, Sabina Y van der Zanden, Marta Cabezuelo, Jacques Neefjes

J Immunol· February 2024

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Spatially and temporally resolved metabolome of the human oral cavity.
Alessio Ciurli, Yassene Mohammed, Christine Ammon, Rico J E Derks, Damien Olivier-Jimenez, Jacques Neefjes

iScience· February 2024

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Metabolic engineering of for biosynthesis of -dimethylated anthracyclines.
Mandy B Hulst, Le Zhang, Helga U van der Heul, Chao Du, Somayah S Elsayed, Jacques J C Neefjes

Front Bioeng Biotechnol· February 2024

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