Publications by authors named "Jacqueto Zephyr"

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Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors.
Leela S Dodda, Sebastien Campos, David Ciccone, Samantha Carreiro, Silvana Leit, Jacqueto Zephyr

J Med Chem· September 2025

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FruitFire: a luciferase based on a fruit fly metabolic enzyme.
Spencer T Adams, Jacqueto Zephyr, Markus F Bohn, Celia A Schiffer, Stephen C Miller

bioRxiv· June 2023

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Allosteric quinoxaline-based inhibitors of the flavivirus NS2B/NS3 protease.
Jacqueto Zephyr, Desaboini Nageswara Rao, Colby Johnson, Ala M Shaqra, Ellen A Nalivaika

Bioorg Chem· February 2023

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Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance.
Jacqueto Zephyr, Desaboini Nageswara Rao, Sang V Vo, Mina Henes, Klajdi Kosovrasti

J Mol Biol· May 2022

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Viral proteases: Structure, mechanism and inhibition.
Jacqueto Zephyr, Nese Kurt Yilmaz, Celia A Schiffer

Enzymes· December 2021

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Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants.
Desaboini Nageswara Rao, Jacqueto Zephyr, Mina Henes, Elise T Chan, Ashley N Matthew

J Med Chem· August 2021

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Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.
Ashley N Matthew, Florian Leidner, Gordon J Lockbaum, Mina Henes, Jacqueto Zephyr

Chem Rev· March 2021

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Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors.
Ashley N Matthew, Jacqueto Zephyr, Desaboini Nageswara Rao, Mina Henes, Wasih Kamran

mBio· March 2020

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Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants.
Ashley N Matthew, Jacqueto Zephyr, Caitlin J Hill, Muhammad Jahangir, Alicia Newton

J Med Chem· July 2017

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