Publications by authors named "Jade Bath"

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Mucins protect against Streptococcus pneumoniae virulence by suppressing pneumolysin expression.
Jade Bath, Elisabet Bjånes, Cengiz Goekeri, Jeff Hsiao, Deniz Uzun

J Clin Invest· August 2024

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Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages.
John Okombo, Sachel Mok, Tarrick Qahash, Tomas Yeo, Jade Bath

PLoS Pathog· October 2022

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Role of MUC5B during Group B Streptococcal Vaginal Colonization.
Lindsey R Burcham, Jade R Bath, Caroline A Werlang, Laurie M Lyon, Naoko Liu

mBio· April 2022

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Mucus.
Abigail McShane, Jade Bath, Ana M Jaramillo, Caroline Ridley, Agnes A Walsh

Curr Biol· August 2021

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K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness.
Barbara H Stokes, Satish K Dhingra, Kelly Rubiano, Sachel Mok, Judith Straimer, Jade R Bath

Elife· July 2021

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The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to parasite resistance.
James M Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F Gnädig

Sci Transl Med· July 2021

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Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series.
Michael J Palmer, Xiaoyi Deng, Shawn Watts, Goran Krilov, Aleksey Gerasyuto, Jade Bath

J Med Chem· May 2021

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Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265.
John White, Satish K Dhingra, Xiaoyi Deng, Farah El Mazouni, Marcus C S Lee, Jade Bath

ACS Infect Dis· January 2019

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Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study.
Alejandro Llanos-Cuentas, Martin Casapia, Raúl Chuquiyauri, Juan-Carlos Hinojosa, Nicola Kerr, Jade Bath

Lancet Infect Dis· August 2018

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