Publications by authors named "Jake Kline"

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Comparative Analysis of Proteoform Clean-Up Methods for In-Depth Top-Down Proteomics.
Alyssa A Williams, Kendalyn N Firenza, Amy K Carfagno, Jake T Kline, Luca Fornelli

Proteomics· December 2025

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Mechanosensor-mediated Hsp70 phosphorylation orchestrates the landscape of the heat shock response.
Siddhi Omkar, Jake T Kline, James H Grissom, Diyun Sun, Richard J Chi

Nat Commun· December 2025

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Top-down mass spectrometry analysis of capsid proteins of recombinant adeno-associated virus using multiple ion activations and proton transfer charge reduction.
Jake T Kline, Jingjing Huang, Linda B Lieu, Kristina Srzentić, David Bergen

Proteomics· March 2025

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Gel-Based Sample Fractionation with SP3-Purification for Top-Down Proteomics.
Ayako Takemori, Naoyuki Sugiyama, Jake T Kline, Luca Fornelli, Nobuaki Takemori

J Proteome Res· February 2025

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Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity.
Siddhi Omkar, Megan M Mitchem, Joel R Hoskins, Courtney Shrader, Jake T Kline

PLoS Genet· December 2024

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Towards a universal method for middle-down analysis of antibodies via proton transfer charge reduction-Orbitrap mass spectrometry.
Ryan N Oates, Linda B Lieu, Jake T Kline, Christopher Mullen, Kristina Srzentić

Anal Bioanal Chem· November 2024

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Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity.
Siddhi Omkar, Courtney Shrader, Joel R Hoskins, Jake T Kline, Megan M Mitchem

bioRxiv· June 2024

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Targeted Quantification of Proteoforms in Complex Samples by Proteoform Reaction Monitoring.
Che-Fan Huang, Jake T Kline, Fernanda Negrão, Matthew T Robey, Timothy K Toby

Anal Chem· February 2024

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Orbitrap Mass Spectrometry and High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) Enable the in-Depth Analysis of Human Serum Proteoforms.
Jake T Kline, Michael W Belford, Cornelia L Boeser, Romain Huguet, Ryan T Fellers

J Proteome Res· November 2023

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Mass spectrometry characterization of antibodies at the intact and subunit levels: from targeted to large-scale analysis.
Jake T Kline, Rafael D Melani, Luca Fornelli

Int J Mass Spectrom· October 2023

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Improved Label-Free Quantification of Intact Proteoforms Using Field Asymmetric Ion Mobility Spectrometry.
Jake T Kline, Michael W Belford, Jingjing Huang, Joseph B Greer, David Bergen

Anal Chem· June 2023

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Multifunctional Nanogenerator-Integrated Metamaterial Concrete Systems for Smart Civil Infrastructure.
Kaveh Barri, Qianyun Zhang, Jake Kline, Wenyun Lu, Jianzhe Luo

Adv Mater· April 2023

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Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications.
Nitika, Bo Zheng, Linhao Ruan, Jake T Kline, Siddhi Omkar

PLoS Biol· October 2022

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Structural and Functional Characterization of a Novel Scorpion Toxin that Inhibits Na1.8 via Interactions With the DI Voltage Sensor and DII Pore Module.
Kiran George, Diego Lopez-Mateos, Tarek Mohamed Abd El-Aziz, Yucheng Xiao, Jake Kline

Front Pharmacol· May 2022

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Sequential Ion-Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer.
Jake T Kline, Christopher Mullen, Kenneth R Durbin, Ryan N Oates, Romain Huguet

J Am Soc Mass Spectrom· September 2021

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Identification and Characterization of Novel Proteins from Arizona Bark Scorpion Venom That Inhibit Nav1.8, a Voltage-Gated Sodium Channel Regulator of Pain Signaling.
Tarek Mohamed Abd El-Aziz, Yucheng Xiao, Jake Kline, Harold Gridley, Alyse Heaston

Toxins (Basel)· July 2021

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Proteomic Profiling of Hsp90 Inhibitors.
Sudhakar Voruganti, Jake T Kline, Maurie J Balch, Janet Rogers, Robert L Matts

Methods Mol Biol· July 2018

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Emerging roles of sumoylation in the regulation of actin, microtubules, intermediate filaments, and septins.
Annabel Alonso, Matt Greenlee, Jessica Matts, Jake Kline, Kayla J Davis

Cytoskeleton (Hoboken)· July 2015

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