Publications by authors named "James B Case"

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The IFIT2-IFIT3 antiviral complex targets short 5' untranslated regions on viral mRNAs for translation inhibition.
Dustin R Glasner, Candace Todd, Brian Cook, Agustina D'Urso, Shivani Khosla, James Brett Case

Nat Microbiol· November 2025

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SARS-CoV-2: The Interplay Between Evolution and Host Immunity.
James Brett Case, Shilpi Jain, Mehul S Suthar, Michael S Diamond

Annu Rev Immunol· April 2025

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Short 5' UTRs serve as a marker for viral mRNA translation inhibition by the IFIT2-IFIT3 antiviral complex.
Dustin R Glasner, Candace Todd, Brian Cook, Agustina D'Urso, Shivani Khosla, James Brett Case

bioRxiv· February 2025

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A trivalent mucosal vaccine encoding phylogenetically inferred ancestral RBD sequences confers pan-Sarbecovirus protection in mice.
James Brett Case, Shilpa Sanapala, Carly Dillen, Victoria Rhodes, Christian Zmasek

Cell Host Microbe· December 2024

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Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates.
Matthew Gagne, Barbara J Flynn, Shayne F Andrew, Josue Marquez, Dillon R Flebbe, James Brett Case

Nat Immunol· October 2024

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A pan-variant miniprotein inhibitor protects against SARS-CoV-2 variants.
Jimin Lee, James Brett Case, Young-Jun Park, Rashmi Ravichandran, Daniel Asarnow

bioRxiv· August 2024

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Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines.
Chieh-Yu Liang, Saravanan Raju, Zhuoming Liu, Yuhao Li, Guha Asthagiri Arunkumar, James Brett Case

Nature· June 2024

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Computationally restoring the potency of a clinical antibody against Omicron.
Thomas A Desautels, Kathryn T Arrildt, Adam T Zemla, Edmond Y Lau, Fangqiang Zhu, James B Case

Nature· May 2024

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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds.
Eike-Christian Wamhoff, Larance Ronsard, Jared Feldman, Grant A Knappe, Blake M Hauser, James Brett Case

Nat Commun· January 2024

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Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates.
Matthew Gagne, Barbara J Flynn, Shayne F Andrew, Dillon R Flebbe, Anna Mychalowych, James Brett Case

bioRxiv· November 2023

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Neutralization, effector function and immune imprinting of Omicron variants.
Amin Addetia, Luca Piccoli, James Brett Case, Young-Jun Park, Martina Beltramello

Nature· September 2023

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Characterization of the SARS-CoV-2 BA.5.5 and BQ.1.1 Omicron variants in mice and hamsters.
James Brett Case, Suzanne M Scheaffer, Tamarand L Darling, Traci L Bricker, Lucas J Adams

J Virol· September 2023

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Characterization of the SARS-CoV-2 BA.5.5 and BQ.1.1 Omicron Variants in Mice and Hamsters.
James Brett Case, Suzanne M Scheaffer, Tamarand L Darling, Traci L Bricker, Lucas J Adams

bioRxiv· May 2023

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Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants.
Thomas A Desautels, Kathryn T Arrildt, Adam T Zemla, Edmond Y Lau, Fangqiang Zhu, James B Case

bioRxiv· April 2023

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A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Vikas Chonira, Young D Kwon, Jason Gorman, James Brett Case, Zhiqiang Ku

Nat Chem Biol· March 2023

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Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants.
Amin Addetia, Luca Piccoli, James Brett Case, Young-Jun Park, Martina Beltramello

bioRxiv· February 2023

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Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains.
James Brett Case, Samantha Mackin, John M Errico, Zhenlu Chong, Emily A Madden

Nat Commun· July 2022

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An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer.
Naveenchandra Suryadevara, Andrea R Shiakolas, Laura A VanBlargan, Elad Binshtein, Rita E Chen, James Brett Case

J Clin Invest· June 2022

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The Translational Landscape of SARS-CoV-2-infected Cells Reveals Suppression of Innate Immune Genes.
Maritza Puray-Chavez, Nakyung Lee, Kasyap Tenneti, Yiqing Wang, Hung R Vuong, James B Case

mBio· June 2022

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Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Andrew C Hunt, James Brett Case, Young-Jun Park, Longxing Cao, Kejia Wu

Sci Transl Med· May 2022

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Ultrapotent and broad neutralization of SARS-CoV-2 variants by modular, tetravalent, bi-paratopic antibodies.
Shane Miersch, Nitin Sharma, Reza Saberianfar, Chao Chen, Francesca Caccuri, James Brett Case

Cell Rep· May 2022

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Potent and pan-neutralization of SARS-CoV-2 variants of concern by DARPins.
Vikas Chonira, Young Do Kwon, Jason Gorman, James Brett Case, Zhiqiang Ku

bioRxiv· May 2022

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Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice.
Baoling Ying, Suzanne M Scheaffer, Bradley Whitener, Chieh-Yu Liang, Oleksandr Dmytrenko, James Brett Case

Cell· April 2022

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Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting.
Blake M Hauser, Maya Sangesland, Kerri J St Denis, Evan C Lam, James Brett Case

Cell Rep· March 2022

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Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice.
Baoling Ying, Suzanne M Scheaffer, Bradley Whitener, Chieh-Yu Liang, Oleksandr Dmytrenko, James Brett Case

bioRxiv· February 2022

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