Publications by authors named "James Broughton"

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Suppression of bacterial cell death underlies the antagonistic interaction between ciprofloxacin and tetracycline.
James Broughton, Achille Fraisse, Meriem El Karoui

Mol Syst Biol· October 2025

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CRISPR-Cas enzymes: The toolkit revolutionizing diagnostics.
Matthew S Verosloff, Sarah J Shapiro, Elizabeth M Hawkins, Emel Alpay, Deepika Verma, James P Broughton

Biotechnol J· July 2022

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COVID-19 Variant Detection with a High-Fidelity CRISPR-Cas12 Enzyme.
Clare L Fasching, Venice Servellita, Bridget McKay, Vaishnavi Nagesh, James P Broughton

J Clin Microbiol· July 2022

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Growth-dependent heterogeneity in the DNA damage response in Escherichia coli.
Sebastián Jaramillo-Riveri, James Broughton, Alexander McVey, Teuta Pilizota, Matthew Scott

Mol Syst Biol· May 2022

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Performance of Patient-Reported Outcomes Measurement Information System (PROMIS) scores compared with legacy metrics in evaluating outcomes after surgical treatment for osteochondritis dissecans of the humeral capitellum.
James Sam Broughton, Charles A Goldfarb, Mitchel R Obey, Matthew V Smith

J Shoulder Elbow Surg· July 2021

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The mA RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor.
Yiren Xiao, Kaushik N Thakkar, Hongjuan Zhao, James Broughton, Yang Li

Proc Natl Acad Sci U S A· September 2020

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Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation.
Ava C Carter, Jin Xu, Meagan Y Nakamoto, Yuning Wei, Brian J Zarnegar, James P Broughton

Elife· May 2020

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Rapid Detection of 2019 Novel Coronavirus SARS-CoV-2 Using a CRISPR-based DETECTR Lateral Flow Assay.
James P Broughton, Xianding Deng, Guixia Yu, Clare L Fasching, Jasmeet Singh

medRxiv· March 2020

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N6-Methyladenosine Modification Controls Circular RNA Immunity.
Y Grace Chen, Robert Chen, Sadeem Ahmad, Rohit Verma, Sudhir Pai Kasturi, James P Broughton

Mol Cell· October 2019

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CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation.
Fatemehsadat Esteghamat, James S Broughton, Emily Smith, Rebecca Cardone, Tarun Tyagi

Nat Genet· August 2019

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RNA structure maps across mammalian cellular compartments.
Lei Sun, Furqan M Fazal, Pan Li, James P Broughton, Byron Lee

Nat Struct Mol Biol· April 2019

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Detection of microRNA-Target Interactions by Chimera PCR (ChimP).
James P Broughton, Amy E Pasquinelli

Methods Mol Biol· March 2019

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Opposing roles of microRNA Argonautes during Caenorhabditis elegans aging.
Antti P Aalto, Ian A Nicastro, James P Broughton, Laura B Chipman, William P Schreiner

PLoS Genet· June 2018

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mA mRNA methylation sustains Treg suppressive functions.
Jiyu Tong, Guangchao Cao, Ting Zhang, Esen Sefik, Maria Carolina Amezcua Vesely, James P Broughton

Cell Res· February 2018

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mA mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.
Hua-Bing Li, Jiyu Tong, Shu Zhu, Pedro J Batista, Erin E Duffy, James P Broughton

Nature· August 2017

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Pairing beyond the Seed Supports MicroRNA Targeting Specificity.
James P Broughton, Michael T Lovci, Jessica L Huang, Gene W Yeo, Amy E Pasquinelli

Mol Cell· October 2016

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A tale of two sequences: microRNA-target chimeric reads.
James P Broughton, Amy E Pasquinelli

Genet Sel Evol· April 2016

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Identifying Argonaute binding sites in Caenorhabditis elegans using iCLIP.
James P Broughton, Amy E Pasquinelli

Methods· September 2013

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TRIM79α, an interferon-stimulated gene product, restricts tick-borne encephalitis virus replication by degrading the viral RNA polymerase.
R Travis Taylor, Kirk J Lubick, Shelly J Robertson, James P Broughton, Marshall E Bloom

Cell Host Microbe· September 2011

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