Publications by authors named "James Fluckey"

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ATG4B is required for mTORC1-mediated anabolic activity and is associated with clinical outcomes in non-small cell lung cancer.
Patrick J Ryan, Bethany C Guerra, Selina Uranga, Jessica M Cardin, Steven E Riechman, James D Fluckey

FEBS Open Bio· October 2025

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Brief ambulatory reloading elevates muscle protein synthesis but does not prevent disuse atrophy in hindlimb-unloaded rats.
Michael P Wiggs, Carla Mc Nascimento, Kevin L Shimkus, James D Fluckey

Biochem Biophys Rep· September 2025

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Metformin ablates high fat diet-induced skeletal muscle hypertrophy and elevation of sarcolemmal GLUT4 when feeding is initiated in young adult male mice.
John M Lawler, Khaled Y Kamal, Rachel E Botchlett, Shih Lung Woo, Honggui Li, James D Fluckey

Connect Tissue Res· March 2025

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MCF7 breast cancer anabolic capacity reduced with CRISPR/Cas9-mediated stable overexpression of DEPTOR.
J William Deaver, Patrick J Ryan, Colleen L O'Reilly, Selina Uranga, Sara Mata López, James D Fluckey

Am J Physiol Cell Physiol· February 2025

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The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle.
Patrick J Ryan, Selina Uranga, Sean T Stanelle, Megan H Lewis, Colleen L O'Reilly, James D Fluckey

Sci Rep· April 2024

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The Effect of Choline and Resistance Training on Strength and Lean Mass in Older Adults.
Chang Woock Lee, Teak V Lee, Elfego Galvan, Vincent C W Chen, Steve Bui, James D Fluckey

Nutrients· September 2023

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Influence of Mechanistic Target of Rapamycin (mTOR)-Regulated Anabolic Pathways on Equine Skeletal Muscle Health.
Pier L Semanchik, Lauren T Wesolowski, Patrick J Ryan, Sarah H White-Springer, James D Fluckey

J Equine Vet Sci· May 2023

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Combined effects of heavy ion exposure and simulated Lunar gravity on skeletal muscle.
Michael P Wiggs, Yang Lee, Kevin L Shimkus, Colleen I O'Reilly, Florence Lima, James D Fluckey

Life Sci Space Res (Amst)· May 2023

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Myokines derived from contracting skeletal muscle suppress anabolism in MCF7 breast cancer cells by inhibiting mTOR.
Amanda R Davis, Chelsea G Goodenough, Kim C Westerlind, Robert Strange, John W Deaver, James D Fluckey

Front Physiol· October 2022

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Ablation of Ghrelin Receptor Mitigates the Metabolic Decline of Aging Skeletal Muscle.
Colleen O'Reilly, Ligen Lin, Hongying Wang, James Fluckey, Yuxiang Sun

Genes (Basel)· July 2022

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Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner.
Seongkyun Lim, J William Deaver, Megan E Rosa-Caldwell, David E Lee, Francielly Morena da Silva, James D Fluckey

Am J Physiol Endocrinol Metab· March 2022

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Use of deuterium oxide (HO) to assess muscle protein synthesis in juvenile red drum (Sciaenops ocellatus) fed complete, and valine-deficient diets.
Sergio Castillo, Fernando Y Yamamoto, Colleen O'Reilly, James D Fluckey, Delbert M Gatlin

Amino Acids· September 2021

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Culprits or consequences: Understanding the metabolic dysregulation of muscle in diabetes.
Colleen L O'Reilly, Selina Uranga, James D Fluckey

World J Biol Chem· September 2021

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Rider Energy Expenditure During High Intensity Horse Activity.
Colleen O'Reilly, Jennifer Zoller, Dennis Sigler, Martha Vogelsang, Jason Sawyer, James Fluckey

J Equine Vet Sci· July 2021

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Interorgan Metabolism of Amino Acids in Human Health and Disease.
Patrick J Ryan, Steven E Riechman, James D Fluckey, Guoyao Wu

Adv Exp Med Biol· July 2021

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Regulation of cellular anabolism by mTOR: or how I learned to stop worrying and love translation.
J William Deaver, Sara Mata López, Patrick J Ryan, Peter P Nghiem, Steven E Riechman, James D Fluckey

Sports Med Health Sci· December 2020

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Regulation of mitochondrial quality following repeated bouts of hindlimb unloading.
Megan E Rosa-Caldwell, Jacob L Brown, Richard A Perry, Kevin L Shimkus, Yasaman Shirazi-Fard, James D Fluckey

Appl Physiol Nutr Metab· March 2020

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Effect of combined fish oil & Curcumin on murine skeletal muscle morphology and stress response proteins during mechanical unloading.
John M Lawler, Erika L Garcia-Villatoro, Vinicius Guzzoni, Jeff M Hord, Rachel Botchlett, James D Fluckey

Nutr Res· May 2019

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The effects of hindlimb unloading versus dietary cholesterol and resistance training on rat skeletal muscle responses.
Teak V Lee, Chang Woock Lee, Vincent C W Chen, Steve Bui, James D Fluckey

Lipids Health Dis· January 2019

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Responses of skeletal muscle size and anabolism are reproducible with multiple periods of unloading/reloading.
Kevin L Shimkus, Yasaman Shirazi-Fard, Michael P Wiggs, Shaik T Ullah, Camilo Pohlenz, James D Fluckey

J Appl Physiol (1985)· November 2018

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Effect of Eukarion-134 on Akt-mTOR signalling in the rat soleus during 7 days of mechanical unloading.
J Matthew Kuczmarski, Jeff M Hord, Yang Lee, Vinicius Guzzoni, Dinah Rodriguez, James D Fluckey

Exp Physiol· April 2018

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Hyperglycemia- and hyperinsulinemia-induced insulin resistance causes alterations in cellular bioenergetics and activation of inflammatory signaling in lymphatic muscle.
Yang Lee, James D Fluckey, Sanjukta Chakraborty, Mariappan Muthuchamy

FASEB J· July 2017

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The influence of chronic IL-6 exposure, in vivo, on rat Achilles tendon extracellular matrix.
Mark S Katsma, Shivam H Patel, Erica Eldon, Kathryn A Corbell, Kevin L Shimkus, James D Fluckey

Cytokine· May 2017

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Acute and chronic safety and efficacy of dose dependent creatine nitrate supplementation and exercise performance.
Elfego Galvan, Dillon K Walker, Sunday Y Simbo, Ryan Dalton, Kyle Levers, James D Fluckey

J Int Soc Sports Nutr· October 2016

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Cumulative Muscle Protein Synthesis and Protein Intake Requirements.
Erin Simmons, James D Fluckey, Steven E Riechman

Annu Rev Nutr· July 2016

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