Publications by authors named "James Kew"

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Dysregulation of Specialized Delay/Interference-Dependent Working Memory Following Loss of Dysbindin-1A in Schizophrenia-Related Phenotypes.
Emilie I Petit, Zuzanna Michalak, Rachel Cox, Colm M P O'Tuathaigh, Niamh Clarke, James N Kew

Neuropsychopharmacology· May 2017

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Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice.
Tracy A Lane, Thomas Boerner, David M Bannerman, James N C Kew, Elizabeth M Tunbridge

BMC Neurosci· September 2013

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A novel series of benzimidazole NR2B-selective NMDA receptor antagonists.
David J Davies, Matthew Crowe, Nolwenn Lucas, Joanna Quinn, David D Miller, James N C Kew

Bioorg Med Chem Lett· April 2012

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Effects of the selective 5-HT(7) receptor antagonist SB-269970 in animal models of psychosis and cognition.
Kerry A Waters, Tania O Stean, Beverley Hammond, David J Virley, Neil Upton, James N C Kew

Behav Brain Res· March 2012

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Activation of α7 nicotinic acetylcholine receptors persistently enhances hippocampal synaptic transmission and prevents Aß-mediated inhibition of LTP in the rat hippocampus.
Tomas Ondrejcak, Qinwen Wang, James N C Kew, David J Virley, Neil Upton

Eur J Pharmacol· February 2012

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Fractionation of spatial memory in GRM2/3 (mGlu2/mGlu3) double knockout mice reveals a role for group II metabotropic glutamate receptors at the interface between arousal and cognition.
Louisa Lyon, Philip W J Burnet, James N C Kew, Corrado Corti, J Nicholas P Rawlins

Neuropsychopharmacology· December 2011

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Hippocampal mossy fiber long-term depression in Grm2/3 double knockout mice.
Louisa Lyon, Melodie Borel, Miriam Carrión, James N C Kew, Corrado Corti

Synapse· September 2011

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Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia.
Michael R Barnes, Julie Huxley-Jones, Peter R Maycox, Mark Lennon, Amy Thornber, James N C Kew

J Neurosci Res· August 2011

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ADAMTSL3 as a candidate gene for schizophrenia: gene sequencing and ultra-high density association analysis by imputation.
David J Dow, Julie Huxley-Jones, Jamie M Hall, Clyde Francks, Peter R Maycox, James N C Kew

Schizophr Res· April 2011

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The muscarinic M(4) receptor is the functionally predominant subtype in rat and mouse striatum as demonstrated using [(35)S] GTPγS binding.
Kathryn L Chapman, Dina Vaswani, Nicola Hendry, Christopher J Langmead, James N C Kew

Eur J Pharmacol· February 2011

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Adenoviral-mediated Cre expression effectively suppresses GlyT1 binding in the thalamic area of GlyT1 conditional knock-out mice.
Chiara Cazzin, Floriana Zanderigo, Vivian J A Costantini, Erika Zambello, Christopher J A Ring, James N C Kew

J Neurosci Methods· November 2010

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Identification of novel alpha7 nAChR positive allosteric modulators with the use of pharmacophore in silico screening methods.
Anna Maria Capelli, Laura Castelletti, Cristian Salvagno, Beatrice Oliosi, Elisa Di Lenarda, James N C Kew

Bioorg Med Chem Lett· August 2010

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Alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators.
Andrew P Lightfoot, James N C Kew, John Skidmore

Prog Med Chem· June 2010

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Glutamate-dopamine crosstalk in the rat prefrontal cortex is modulated by Alpha7 nicotinic receptors and potentiated by PNU-120596.
Phil D Livingstone, Jane A Dickinson, Jayaraman Srinivasan, James N C Kew, Susan Wonnacott

J Mol Neurosci· January 2010

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Investigation of the H(+)-myo-inositol transporter (HMIT) as a neuronal regulator of phosphoinositide signalling.
Elena Di Daniel, James N Kew, Peter R Maycox

Biochem Soc Trans· October 2009

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Electrophysiological characterisation of the actions of kynurenic acid at ligand-gated ion channels.
M H Selina Mok, Anne-Cécile Fricker, Annette Weil, James N C Kew

Neuropharmacology· September 2009

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Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential.
Laetitia Mony, James N C Kew, Martin J Gunthorpe, Pierre Paoletti

Br J Pharmacol· August 2009

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Effects of N-acetylaspartylglutamate (NAAG) at group II mGluRs and NMDAR.
Anne-Cécile Fricker, M H Selina Mok, Raúl de la Flor, Ajit J Shah, Marie Woolley, James N C Kew

Neuropharmacology· July 2009

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Evaluation of expression and function of the H+/myo-inositol transporter HMIT.
Elena Di Daniel, Man H S Mok, Emma Mead, Chiara Mutinelli, Erika Zambello, James N C Kew

BMC Cell Biol· July 2009

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alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex.
Phil D Livingstone, Jayaraman Srinivasan, James N C Kew, Lee A Dawson, Cecilia Gotti

Eur J Neurosci· February 2009

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Investigation of G72 (DAOA) expression in the human brain.
Isabel Benzel, James N C Kew, Ramya Viknaraja, Fiona Kelly, Jacqueline de Belleroche

BMC Psychiatry· December 2008

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Altered hippocampal expression of glutamate receptors and transporters in GRM2 and GRM3 knockout mice.
Louisa Lyon, James N C Kew, Corrado Corti, Paul J Harrison, Philip W J Burnet

Synapse· November 2008

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Presynaptic alpha 7- and beta 2-containing nicotinic acetylcholine receptors modulate excitatory amino acid release from rat prefrontal cortex nerve terminals via distinct cellular mechanisms.
Jane A Dickinson, James N C Kew, Susan Wonnacott

Mol Pharmacol· August 2008

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Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists.
Thomas J Woltering, Jürgen Wichmann, Erwin Goetschi, Geo Adam, James N C Kew

Bioorg Med Chem Lett· April 2008

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Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: part 2. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists.
Thomas J Woltering, Geo Adam, Jürgen Wichmann, Erwin Goetschi, James N C Kew

Bioorg Med Chem Lett· February 2008

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