Publications by authors named "James Leo"

Claim this Profile

Mentions over time

Mentions by platform

Video Views

36

Total Likes

75

Extended Reach

522,786

Social Features

27
S
State-selective small molecule degraders that preferentially remove aggregates and oligomers.
Jakub Luptak, Dean Clift, Aamir Mukadam, Jonathan Benn, Tyler Rhinesmith, Leo C James

Nat Commun· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Author Correction: HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly.
Nadine Renner, Alex Kleinpeter, Donna L Mallery, Anna Albecka, K M Rifat Faysal, Leo C James

Nat Struct Mol Biol· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The host protein cyclophilin A inhibits HIV-1 nuclear entry by decreasing capsid elasticity.
Jun Hong, Akshay Deshpande, Yatish Thakare, Lora Simonovsky, AidanDarian W Douglas, Leo C James

bioRxiv· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An intranasal subunit vaccine induces protective systemic and mucosal antibody immunity against respiratory viruses in mouse models.
Aina Karen Anthi, Anette Kolderup, Eline Benno Vaage, Malin Bern, Sopisa Benjakul, Leo C James

Nat Commun· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
How HIV-1 Uses the Metabolite Inositol Hexakisphosphate to Build Its Capsid.
Leo C James

Viruses· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The central pore of HIV-1 capsomers promotes sustained stability of the viral capsid.
Alex B Kleinpeter, Donna L Mallery, Anna Albecka, Ryan C Burdick, Nadine Renner, Leo C James

bioRxiv· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
UbiREAD deciphers proteasomal degradation code of homotypic and branched K48 and K63 ubiquitin chains.
Leo Kiss, Leo C James, Brenda A Schulman

Mol Cell· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Co-opting templated aggregation to degrade pathogenic tau assemblies and improve motor function.
Lauren V C Miller, Guido Papa, Marina Vaysburd, Shi Cheng, Paul W Sweeney, Leo C James

Cell· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21.
Shanna S Leventhal, Thomas Bisom, Dean Clift, Deepashri Rao, Kimberly Meade-White, Leo C James

Nat Commun· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Human coronaviruses activate and hijack the host transcription factor HSF1 to enhance viral replication.
Silvia Pauciullo, Anna Riccio, Silvia Santopolo, Anna Albecka, Guido Papa, Leo C James

Cell Mol Life Sci· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HIV-1 adapts to lost IP6 coordination through second-site mutations that restore conical capsid assembly.
Alex Kleinpeter, Donna L Mallery, Nadine Renner, Anna Albecka, J Ole Klarhof, Leo C James

Nat Commun· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Aggregate-selective removal of pathological tau by clustering-activated degraders.
Jonathan Benn, Shi Cheng, Sophie Keeling, Annabel E Smith, Marina J Vaysburd, Leo C James

Science· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The type-I interferon response potentiates seeded tau aggregation and exacerbates tau pathology.
Sophie A I Sanford, Lauren V C Miller, Marina Vaysburd, Sophie Keeling, Benjamin J Tuck, Leo C James

Alzheimers Dement· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure.
K M Rifat Faysal, James C Walsh, Nadine Renner, Chantal L Márquez, Vaibhav B Shah, Leo C James

Elife· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery.
Sopisa Benjakul, Aina Karen Anthi, Anette Kolderup, Marina Vaysburd, Heidrun Elisabeth Lode, Leo C James

PNAS Nexus· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation.
Alice Fletcher, Dean Clift, Emma de Vries, Sergio Martinez Cuesta, Timothy Malcolm, Leo James

Nat Commun· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SLN124, a GalNAc conjugated 19-mer siRNA targeting tmprss6, reduces plasma iron and increases hepcidin levels of healthy volunteers.
John B Porter, Alison Scrimgeour, Alberto Martinez, Leo James, Manuela Aleku

Am J Hematol· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Effect of Inositol Hexakisphosphate on HIV-1 Particle Production and Infectivity can be Modulated by Mutations that Affect the Stability of the Immature Gag Lattice.
Alex B Kleinpeter, Yanan Zhu, Donna L Mallery, Sherimay D Ablan, Long Chen, Leo C James

J Mol Biol· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
IP6-stabilised HIV capsids evade cGAS/STING-mediated host immune sensing.
Guido Papa, Anna Albecka, Donna Mallery, Marina Vaysburd, Nadine Renner, Leo C James

EMBO Rep· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
James C V Stacey, Aaron Tan, John M Lu, Leo C James, Robert A Dick

Proc Natl Acad Sci U S A· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
Leo Kiss, Tyler Rhinesmith, Jakub Luptak, Claire F Dickson, Jonas Weidenhausen, Leo C James

Nat Commun· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly.
Nadine Renner, Alex Kleinpeter, Donna L Mallery, Anna Albecka, K M Rifat Faysal, Leo C James

Nat Struct Mol Biol· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models.
Aamir S Mukadam, Lauren V C Miller, Annabel E Smith, Marina Vaysburd, Siri A Sakya, Leo C James

Science· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evasion of cGAS and TRIM5 defines pandemic HIV.
Lorena Zuliani-Alvarez, Morten L Govasli, Jane Rasaiyaah, Chris Monit, Stephen O Perry, Leo C James

Nat Microbiol· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis