Publications by authors named "James Maggs"

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Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.
Vincent L M Yip, Henry Pertinez, Xiaoli Meng, James L Maggs, Daniel F Carr

Br J Clin Pharmacol· June 2021

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Persistent Hepatitis E virus infection across England and Wales 2009-2017: Demography, virology and outcomes.
Michael Ankcorn, Bengü Said, Dilys Morgan, Ahmed M Elsharkawy, James Maggs

J Viral Hepat· February 2021

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Definition of Haptens Derived from Sulfamethoxazole: In Vitro and in Vivo.
Arun Tailor, James C Waddington, Jane Hamlett, James Maggs, Laila Kafu

Chem Res Toxicol· October 2019

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Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury.
Ian M Copple, Wouter den Hollander, Giulia Callegaro, Fiona E Mutter, James L Maggs

Arch Toxicol· February 2019

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Cochrane systematic review highlights the importance of lactulose in the management of hepatic encephalopathy.
Anna Sutherland, Faeqa Hami, James Maggs

BMJ Support Palliat Care· June 2018

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Dapsone and Nitroso Dapsone Activation of Naı̈ve T-Cells from Healthy Donors.
Abdulaziz Alzahrani, Monday Ogese, Xiaoli Meng, James C Waddington, Arun Tailor, James L Maggs

Chem Res Toxicol· December 2017

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Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from Epoxide Metabolites of Carbamazepine in Patients.
Vincent L M Yip, Xiaoli Meng, James L Maggs, Rosalind E Jenkins, Philippe T Marlot

Chem Res Toxicol· July 2017

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Characterization of the Specificity, Functionality, and Durability of Host T-Cell Responses Against the Full-Length Hepatitis E Virus.
Anthony Brown, John S Halliday, Leo Swadling, Richie G Madden, Richard Bendall, James Maggs

Hepatology· December 2016

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Development and validation of a dynamic outcome prediction model for paracetamol-induced acute liver failure: a cohort study.
William Bernal, Yanzhong Wang, James Maggs, Christopher Willars, Elizabeth Sizer

Lancet Gastroenterol Hepatol· November 2016

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Auto-oxidation of Isoniazid Leads to Isonicotinic-Lysine Adducts on Human Serum Albumin.
Xiaoli Meng, James L Maggs, Toru Usui, Paul Whitaker, Neil S French

Chem Res Toxicol· January 2015

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Characterization of Peroxidases Expressed in Human Antigen Presenting Cells and Analysis of the Covalent Binding of Nitroso Sulfamethoxazole to Myeloperoxidase.
Monday O Ogese, Rosalind E Jenkins, James L Maggs, Xiaoli Meng, Paul Whitaker

Chem Res Toxicol· January 2015

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Mass spectrometric characterization of circulating covalent protein adducts derived from a drug acyl glucuronide metabolite: multiple albumin adductions in diclofenac patients.
Thomas G Hammond, Xiaoli Meng, Rosalind E Jenkins, James L Maggs, Anahi Santoyo Castelazo

J Pharmacol Exp Ther· August 2014

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Abacavir forms novel cross-linking abacavir protein adducts in patients.
Xiaoli Meng, Alexandre S Lawrenson, Neil G Berry, James L Maggs, Neil S French

Chem Res Toxicol· April 2014

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Quantification of urinary mevalonic acid as a biomarker of HMG-CoA reductase activity by a novel translational LC-MS/MS method.
Alison V M Rodrigues, James L Maggs, Stephen J McWilliam, Munir Pirmohamed, Muireann Coen

Bioanalysis· April 2014

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Convenient syntheses of halo-dibenz[b,f]azepines and carbamazepine analogues via N-arylindoles.
Emma-Claire Elliott, James L Maggs, B Kevin Park, Paul M O'Neill, Andrew V Stachulski

Org Biomol Chem· December 2013

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Oxidative bioactivation of abacavir in subcellular fractions of human antigen presenting cells.
Catherine C Bell, Anahi Santoyo Castelazo, Emma L Yang, James L Maggs, Rosalind E Jenkins

Chem Res Toxicol· July 2013

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Mortality and the risk of malignancy in autoimmune liver diseases: a population-based study in Canterbury, New Zealand.
Mohamed I F Shariff, James Maggs, Michael A Heneghan

Hepatology· April 2013

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Haloarene derivatives of carbamazepine with reduced bioactivation liabilities: 2-monohalo and 2,8-dihalo derivatives.
Emma-Claire Elliott, Sophie L Regan, James L Maggs, Elizabeth R Bowkett, Laura J Parry

J Med Chem· November 2012

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Comparison of the reactivity of antimalarial 1,2,4,5-tetraoxanes with 1,2,4-trioxolanes in the presence of ferrous iron salts, heme, and ferrous iron salts/phosphatidylcholine.
Fatima Bousejra-El Garah, Michael He-Long Wong, Richard K Amewu, Sant Muangnoicharoen, James L Maggs

J Med Chem· October 2011

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Convenient syntheses of benzo-fluorinated dibenz[b,f]azepines: rearrangements of isatins, acridines, and indoles.
Emma-Claire Elliott, Elizabeth R Bowkett, James L Maggs, John Bacsa, B Kevin Park

Org Lett· October 2011

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Direct evidence for the formation of diastereoisomeric benzylpenicilloyl haptens from benzylpenicillin and benzylpenicillenic acid in patients.
Xiaoli Meng, Rosalind E Jenkins, Neil G Berry, James L Maggs, John Farrell

J Pharmacol Exp Ther· September 2011

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The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials.
Amy E Mercer, Ian M Copple, James L Maggs, Paul M O'Neill, B Kevin Park

J Biol Chem· January 2011

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Acyl glucuronides: the good, the bad and the ugly.
Sophie L Regan, James L Maggs, Thomas G Hammond, Craig Lambert, Dominic P Williams

Biopharm Drug Dispos· October 2010

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Quantifying the metabolic activation of nevirapine in patients by integrated applications of NMR and mass spectrometries.
Abhishek Srivastava, Lu-Yun Lian, James L Maggs, Masautso Chaponda, Munir Pirmohamed

Drug Metab Dispos· January 2010

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Metabolic and chemical origins of cross-reactive immunological reactions to arylamine benzenesulfonamides: T-cell responses to hydroxylamine and nitroso derivatives.
J Luis Castrejon, Sidonie N Lavergne, Ayman El-Sheikh, John Farrell, James L Maggs

Chem Res Toxicol· January 2010

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