Publications by authors named "James R Springstead"

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Chronic sensing of host-derived lipids is an all-in-one signal that primes and activates NLRP3.
Océane Dufies, Marco Di Gioia, Roberto Spreafico, Piao J Tan, James R Springstead

bioRxiv· October 2025

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Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infections.
Marco Di Gioia, Valentina Poli, Piao J Tan, Roberto Spreafico, Anne Chu, James R Springstead

Immunity· September 2025

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Sustainable and Eco-Friendly DLC Fabrication for Replacing Chrome on a Gravure Cylinder Surface.
Chandramohan Seetharamiahsrinivasaraju, Ronit Shetty, Swati Sood, Donald K Cohen, Priyanka Sharma, James R Springstead

Langmuir· February 2024

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Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter.
Marco Di Gioia, Valentina Poli, Piao J Tan, Roberto Spreafico, Anne Chu, James R Springstead

bioRxiv· November 2023

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Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation.
Marco Di Gioia, Roberto Spreafico, James R Springstead, Michael M Mendelson, Roby Joehanes

Nat Immunol· January 2020

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By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation.
Ivan Zanoni, Yunhao Tan, Marco Di Gioia, James R Springstead, Jonathan C Kagan

Immunity· October 2017

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Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells.
Nicholas T Hogan, Michael B Whalen, Lindsey K Stolze, Nizar K Hadeli, Michael T Lam, James R Springstead

Elife· June 2017

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Prostate cancer recognition based on mass spectrometry sensing data and data fingerprint recovery.
Khalfalla Awedat, Ikhlas Abdel-Qader, James R Springstead

Biomed Signal Process Control· March 2017

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An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells.
Ivan Zanoni, Yunhao Tan, Marco Di Gioia, Achille Broggi, Jianbin Ruan, James R Springstead

Science· June 2016

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HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms.
Benjamin Emert, Yehudit Hasin-Brumshtein, James R Springstead, Ladan Vakili, Judith A Berliner

J Lipid Res· August 2014

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An epoxyisoprostane is a major regulator of endothelial cell function.
Wei Zhong, James R Springstead, Ramea Al-Mubarak, Sangderk Lee, Rongsong Li

J Med Chem· November 2013

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A novel approach to oral apoA-I mimetic therapy.
Arnab Chattopadhyay, Mohamad Navab, Greg Hough, Feng Gao, David Meriwether, James R Springstead

J Lipid Res· April 2013

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Role of phospholipid oxidation products in atherosclerosis.
Sangderk Lee, Konstantin G Birukov, Casey E Romanoski, James R Springstead, Aldons J Lusis

Circ Res· August 2012

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Evidence for the importance of OxPAPC interaction with cysteines in regulating endothelial cell function.
James R Springstead, B Gabriel Gugiu, Sangderk Lee, Seung Cha, Andrew D Watson

J Lipid Res· July 2012

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Metalloproteinase processing of HBEGF is a proximal event in the response of human aortic endothelial cells to oxidized phospholipids.
Sangderk Lee, James R Springstead, Brian W Parks, Casey E Romanoski, Roland Palvolgyi

Arterioscler Thromb Vasc Biol· May 2012

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Characterization of a key trifunctional enzyme for aromatic amino acid biosynthesis in Archaeoglobus fulgidus.
Sierin Lim, James R Springstead, Marcella Yu, Wojciech Bartkowski, Imke Schröder

Extremophiles· January 2009

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Effect of growth temperature on ether lipid biochemistry in Archaeoglobus fulgidus.
Denton Lai, James R Springstead, Harold G Monbouquette

Extremophiles· March 2008

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