Publications by authors named "James Whiteaker"

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Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis.
Subramanyam J Tantry, Shankar D Markad, Vikas Shinde, Jyothi Bhat, Gayathri Balakrishnan, James Whiteaker

J Med Chem· February 2017

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Homologous Recombination within Large Chromosomal Regions Facilitates Acquisition of β-Lactam and Vancomycin Resistance in Enterococcus faecium.
Mónica García-Solache, Francois Lebreton, Robert E McLaughlin, James D Whiteaker, Michael S Gilmore

Antimicrob Agents Chemother· October 2016

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Selection and molecular characterization of ceftazidime/avibactam-resistant mutants in Pseudomonas aeruginosa strains containing derepressed AmpC.
Sushmita D Lahiri, Grant K Walkup, James D Whiteaker, Tiffany Palmer, Kathy McCormack

J Antimicrob Chemother· February 2016

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Molecular characterization of MRSA isolates bracketing the current EUCAST ceftaroline-susceptible breakpoint for Staphylococcus aureus: the role of PBP2a in the activity of ceftaroline.
Sushmita D Lahiri, Robert E McLaughlin, James D Whiteaker, Jane E Ambler, Richard A Alm

J Antimicrob Chemother· September 2015

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Characterization of the novel DNA gyrase inhibitor AZD0914: low resistance potential and lack of cross-resistance in Neisseria gonorrhoeae.
Richard A Alm, Sushmita D Lahiri, Amy Kutschke, Linda G Otterson, Robert E McLaughlin, James D Whiteaker

Antimicrob Agents Chemother· March 2015

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Small-molecule inhibitors of gram-negative lipoprotein trafficking discovered by phenotypic screening.
Sarah M McLeod, Paul R Fleming, Kathleen MacCormack, Robert E McLaughlin, James D Whiteaker

J Bacteriol· March 2015

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The resistome of Pseudomonas aeruginosa in relationship to phenotypic susceptibility.
Veronica N Kos, Maxime Déraspe, Robert E McLaughlin, James D Whiteaker, Paul H Roy

Antimicrob Agents Chemother· January 2015

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Overexpression of Pseudomonas aeruginosa LpxC with its inhibitors in an acrB-deficient Escherichia coli strain.
Ning Gao, Sarah M McLeod, Laurel Hajec, Nelson B Olivier, Sushmita D Lahiri, James D Whiteaker

Protein Expr Purif· December 2014

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Diarylthiazole: an antimycobacterial scaffold potentially targeting PrrB-PrrA two-component system.
Eknath Bellale, Maruti Naik, Varun V B, Anisha Ambady, Ashwini Narayan, James Whiteaker

J Med Chem· August 2014

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Lead optimization of 1,4-azaindoles as antimycobacterial agents.
Pravin S Shirude, Radha K Shandil, M R Manjunatha, Claire Sadler, Manoranjan Panda, James Whiteaker

J Med Chem· July 2014

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4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.
Maruti Naik, Vaishali Humnabadkar, Subramanyam J Tantry, Manoranjan Panda, Ashwini Narayan, James Whiteaker

J Med Chem· June 2014

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Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.
Pravin S Shirude, Radha Shandil, Claire Sadler, Maruti Naik, Vinayak Hosagrahara, James Whiteaker

J Med Chem· December 2013

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A homogeneous, high-throughput-compatible, fluorescence intensity-based assay for UDP-N-acetylenolpyruvylglucosamine reductase (MurB) with nanomolar product detection.
Adam B Shapiro, Stephania Livchak, Ning Gao, James Whiteaker, Jason Thresher

J Biomol Screen· March 2012

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A high-throughput absorbance-based assay for methionine produced by methionine aminopeptidase using S-adenosyl-L-methionine synthetase.
Adam B Shapiro, Ning Gao, Jason Thresher, Grant K Walkup, James Whiteaker

J Biomol Screen· June 2011

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