Publications by authors named "Jamin D Steffen"

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Detection of Hotspot Mutations in Cell-Free DNA from the Urine of Hepatocellular Carcinoma Patients.
Selena Y Lin, Ting-Tsung Chang, Jamin D Steffen, Sitong Chen, Surbhi Jain

Diagnostics (Basel)· August 2021

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Structural basis for allosteric PARP-1 retention on DNA breaks.
Levani Zandarashvili, Marie-France Langelier, Uday Kiran Velagapudi, Mark A Hancock, Jamin D Steffen

Science· April 2020

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Purification of DNA Damage-Dependent PARPs from E. coli for Structural and Biochemical Analysis.
Marie-France Langelier, Jamin D Steffen, Amanda A Riccio, Michael McCauley, John M Pascal

Methods Mol Biol· April 2018

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Characterization of the hepatitis B virus DNA detected in urine of chronic hepatitis B patients.
Surbhi Jain, Ying-Hsiu Su, Yih-Ping Su, Sierra McCloud, Ruixia Xue, Jamin D Steffen

BMC Gastroenterol· March 2018

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ChimericSeq: An open-source, user-friendly interface for analyzing NGS data to identify and characterize viral-host chimeric sequences.
Fwu-Shan Shieh, Patrick Jongeneel, Jamin D Steffen, Selena Lin, Surbhi Jain

PLoS One· October 2017

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Detection of urine DNA markers for monitoring recurrent hepatocellular carcinoma.
Hie-Won Hann, Surbhi Jain, Grace Park, Jamin D Steffen, Wei Song

Hepatoma Res· June 2017

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Fluorescent sensors of PARP-1 structural dynamics and allosteric regulation in response to DNA damage.
Jamin D Steffen, Michael M McCauley, John M Pascal

Nucleic Acids Res· November 2016

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PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain.
Jennine M Dawicki-McKenna, Marie-France Langelier, Jamie E DeNizio, Amanda A Riccio, Connie D Cao, Jamin D Steffen

Mol Cell· December 2015

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Discovery and structure-activity relationship of novel 2,3-dihydrobenzofuran-7-carboxamide and 2,3-dihydrobenzofuran-3(2H)-one-7-carboxamide derivatives as poly(ADP-ribose)polymerase-1 inhibitors.
Maulik R Patel, Aaditya Bhatt, Jamin D Steffen, Adel Chergui, Junko Murai

J Med Chem· July 2014

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Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer.
Jamin D Steffen, Renee M Tholey, Marie-France Langelier, Jamie L Planck, Matthew J Schiewer

Cancer Res· January 2014

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Structural Implications for Selective Targeting of PARPs.
Jamin D Steffen, Jonathan R Brody, Roger S Armen, John M Pascal

Front Oncol· December 2013

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New players to the field of ADP-ribosylation make the final cut.
Jamin D Steffen, John M Pascal

EMBO J· May 2013

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Discovery and structure-activity relationships of modified salicylanilides as cell permeable inhibitors of poly(ADP-ribose) glycohydrolase (PARG).
Jamin D Steffen, Donna L Coyle, Komath Damodaran, Paul Beroza, Myron K Jacobson

J Med Chem· August 2011

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Investigation of the lactam side chain length necessary for optimal indenoisoquinoline topoisomerase I inhibition and cytotoxicity in human cancer cell cultures.
Andrew Morrell, Michael S Placzek, Jamin D Steffen, Smitha Antony, Keli Agama

J Med Chem· May 2007

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