Publications by authors named "Jan Cools"

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Deriving lessons learned from monitoring adaptation activities in projects under the EU mission on adaptation.
Stephanie Bilgram, Carla Klusmann, Christian Kind, Elisa Andreoli, Chiara Castellani, Jan Cools

Open Res Eur· November 2025

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Xq24/ aberrations as key drivers of female bias in primary mediastinal large B-cell lymphoma.
Lukas Marcelis, Ryan Nicolaas Allsop, Marlies Vanden Bempt, Koen Debackere, Félicien Renard, Jan Cools

Hemasphere· September 2025

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TLE4 is a repressor of the oncogenic activity of TLX3 in T-cell acute lymphoblastic leukemia.
Lukas Lauwereins, Quentin Van Thillo, Sofie Demeyer, Nicole Mentens, Sarah Provost, Jan Cools

Leukemia· March 2025

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Single-cell DNA and surface protein characterization of high hyperdiploid acute lymphoblastic leukemia at diagnosis and during treatment.
Margo Aertgeerts, Sarah Meyers, Olga Gielen, Jochen Lamote, Barbara Dewaele, Jan Cools

Hemasphere· February 2025

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The unexpected and unresolved roles of PDGFRA and PDGFRB in T-cell acute lymphoblastic leukemia.
Krista Verhoeft, Jan Cools

Haematologica· November 2024

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Unlocking the Complexity: Exploration of Acute Lymphoblastic Leukemia at the Single Cell Level.
Margo Aertgeerts, Sarah Meyers, Sofie Demeyer, Heidi Segers, Jan Cools

Mol Diagn Ther· November 2024

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Single-cell CRISPR screening characterizes transcriptional deregulation in T-cell acute lymphoblastic leukemia.
Sarah Meyers, Olga Gielen, Jan Cools, Sofie Demeyer

Haematologica· October 2024

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Framework for mapping large-scale nature-based solutions for drought mitigation: Regional application in Flanders.
Estifanos Addisu Yimer, Lien De Trift, Stefaan Dondeyne, Lara Speijer, Marijke Huysmans, Jan Cools

Water Res· September 2024

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Selective targeting of malignant T cells.
Charles E de Bock, Jan Cools

Nat Cancer· June 2024

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Single cell RNA sequencing reveals endothelial cell killing and resolution pathways in experimental malaria-associated acute respiratory distress syndrome.
Emilie Pollenus, Hendrik Possemiers, Sofie Knoops, Fran Prenen, Leen Vandermosten, Jan Cools

PLoS Pathog· January 2024

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A review of economic assessments of drought risk reduction approaches in agriculture.
Sam Vermeulen, Jan Cools, Jan Staes, Steven Van Passel

J Environ Manage· November 2023

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CRISPR screening in hematology research: from bulk to single-cell level.
Sarah Meyers, Sofie Demeyer, Jan Cools

J Hematol Oncol· October 2023

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Combination therapy of a PSEN1-selective γ-secretase inhibitor with dexamethasone and an XPO1 inhibitor to target T-cell acute lymphoblastic leukemia.
Charlien Vandersmissen, Cristina Prieto, Olga Gielen, Kris Jacobs, David Nittner, Jan Cools

Haematologica· September 2023

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Targeting STAT5B in T-cell acute lymphoblastic leukemia.
Alexandra Veloso, Jan Cools

Blood· July 2023

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Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer.
Elien Heylen, Paulien Verstraete, Linde Van Aerschot, Shauni L Geeraerts, Tom Venken, Jan Cools

Br J Cancer· May 2023

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A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.
Patricia Altea-Manzano, Ginevra Doglioni, Yawen Liu, Alejandro M Cuadros, Emma Nolan, Jan Cools

Nat Cancer· March 2023

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Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma.
Marlies Vanden Bempt, Koen Debackere, Sofie Demeyer, Quentin Van Thillo, Nienke Meeuws, Jan Cools

Blood· December 2022

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TAL1 cooperates with PI3K/AKT pathway activation in T-cell acute lymphoblastic leukemia.
Naomi Thielemans, Sofie Demeyer, Nicole Mentens, Olga Gielen, Sarah Provost, Jan Cools

Haematologica· October 2022

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Primary mediastinal large B-cell lymphoma is characterized by large-scale copy-neutral loss of heterozygosity.
Stefania Tuveri, Koen Debackere, Lukas Marcelis, Nicolas Dierckxsens, Jonas Demeulemeester, Jan Cools

Genes Chromosomes Cancer· October 2022

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Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.
Matteo Rossi, Patricia Altea-Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Jan Cools

Nature· September 2022

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Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters.
Noortje van Gils, Han J M P Verhagen, Michaël Broux, Tania Martiáñez, Fedor Denkers, Jan Cools

iScience· September 2022

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The Updated European Hematology Association Research Roadmap.
Andreas Engert, Francesco Cerisoli, Jan Cools

Hemasphere· June 2022

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Optimizing the diagnostic workflow for acute lymphoblastic leukemia by optical genome mapping.
Katrina Rack, Jolien De Bie, Geneviève Ameye, Olga Gielen, Sofie Demeyer, Jan Cools

Am J Hematol· May 2022

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PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.
Matteo Rossi, Patricia Altea-Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Jan Cools

Nature· May 2022

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Monitoring of Leukemia Clones in B-cell Acute Lymphoblastic Leukemia at Diagnosis and During Treatment by Single-cell DNA Amplicon Sequencing.
Sarah Meyers, Llucia Alberti-Servera, Olga Gielen, Margot Erard, Toon Swings, Jan Cools

Hemasphere· April 2022

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