Publications by authors named "Jan Madacki"

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Evaluation of the role of and in the dominant multidrug-resistant clone B0/W148.
Isabelle Bonnet, Mickael Orgeur, Florence Brossier, Fadel Sayes, Wafa Frigui, Jan Madacki

Microbiol Spectr· July 2025

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Evolution and emergence of Mycobacterium tuberculosis.
Mickael Orgeur, Camille Sous, Jan Madacki, Roland Brosch

FEMS Microbiol Rev· March 2024

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The MtZ Strain: Molecular Characteristics and Outbreak Investigation of the Most Successful Strain in Aragon Using Whole-Genome Sequencing.
Jessica Comín, Jan Madacki, Isabel Rabanaque, María Zúñiga-Antón, Daniel Ibarz

Front Cell Infect Microbiol· June 2022

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ESX-1-Independent Horizontal Gene Transfer by Mycobacterium tuberculosis Complex Strains.
Jan Madacki, Mickael Orgeur, Guillem Mas Fiol, Wafa Frigui, Laurence Ma

mBio· May 2021

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Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives.
Jan Madacki, Martin Kopál, Mary Jackson, Jana Korduláková

Int J Mol Sci· March 2021

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Mycobacterial virulence: impact on immunogenicity and vaccine research.
Vera M Kroesen, Jan Madacki, Wafa Frigui, Fadel Sayes, Roland Brosch

F1000Res· June 2020

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New Insights into the Mechanism of Action of the Thienopyrimidine Antitubercular Prodrug TP053.
Laurent R Chiarelli, Elena G Salina, Giorgia Mori, Tatyana Azhikina, Olga Riabova, Jan Madacki

ACS Infect Dis· February 2020

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Update on the virulence factors of the obligate pathogen Mycobacterium tuberculosis and related tuberculosis-causing mycobacteria.
Jan Madacki, Guillem Mas Fiol, Roland Brosch

Infect Genet Evol· August 2019

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New lipophilic isoniazid derivatives and their 1,3,4-oxadiazole analogues: Synthesis, antimycobacterial activity and investigation of their mechanism of action.
Rudolf Vosátka, Martin Krátký, Markéta Švarcová, Jiří Janoušek, Jiřina Stolaříková, Jan Madacki

Eur J Med Chem· May 2018

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Impact of the epoxide hydrolase EphD on the metabolism of mycolic acids in mycobacteria.
Jan Madacki, Françoise Laval, Anna Grzegorzewicz, Anne Lemassu, Monika Záhorszká

J Biol Chem· April 2018

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Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity.
Paulo F M Oliveira, Brigitte Guidetti, Alain Chamayou, Christiane André-Barrès, Jan Madacki

Molecules· September 2017

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Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression.
Giulia Degiacomi, Andrej Benjak, Jan Madacki, Francesca Boldrin, Roberta Provvedi

Sci Rep· February 2017

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Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis.
Tetiana Matviiuk, Jan Madacki, Giorgia Mori, Beatrice Silvia Orena, Christophe Menendez

Eur J Med Chem· November 2016

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Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth.
Aurélien Chollet, Giorgia Mori, Christophe Menendez, Frédéric Rodriguez, Isabelle Fabing, Jan Madacki

Eur J Med Chem· August 2015

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An ethA-ethR-deficient Mycobacterium bovis BCG mutant displays increased adherence to mammalian cells and greater persistence in vivo, which correlate with altered mycolic acid composition.
Michelle Lay Teng Ang, Siti Zarina Zainul Rahim, Guanghou Shui, Petronela Dianiškova, Jan Madacki

Infect Immun· May 2014

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A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone.
Anna E Grzegorzewicz, Jana Korduláková, Victoria Jones, Sarah E M Born, Juan M Belardinelli, Jan Madacki

J Biol Chem· November 2012

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