Publications by authors named "Jan Sap"

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Protein tyrosine phosphatase-α amplifies transforming growth factor-β-dependent profibrotic signaling in lung fibroblasts.
Yael Aschner, Meghan Nelson, Matthew Brenner, Helen Roybal, Keriann Beke, Jan Sap

Am J Physiol Lung Cell Mol Physiol· August 2020

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Loss-of-function of PTPR γ and ζ, observed in sporadic schizophrenia, causes brain region-specific deregulation of monoamine levels and altered behavior in mice.
Arnaud Cressant, Veronique Dubreuil, Jing Kong, Thorsten Manfred Kranz, Francoise Lazarini, Jan Sap

Psychopharmacology (Berl)· February 2017

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Receptor Protein Tyrosine Phosphatase α-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice.
Stephanie M Stanford, Mattias N D Svensson, Cristiano Sacchetti, Caila A Pilo, Dennis J Wu, Jan Sap

Arthritis Rheumatol· February 2016

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An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions.
Guillermo A Gomez, Robert W McLachlan, Selwin K Wu, Benjamin J Caldwell, Elliott Moussa, Jan Sap

Mol Biol Cell· April 2015

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Protein tyrosine phosphatase regulation of stem and progenitor cell biology.
Veronique Dubreuil, Jan Sap, Sheila Harroch

Semin Cell Dev Biol· January 2015

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RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin.
Marta Truffi, Véronique Dubreuil, Xuan Liang, Nathalie Vacaresse, Fabienne Nigon, Jan Sap

J Cell Sci· June 2014

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Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness.
Yael Aschner, Anthony P Khalifah, Natalie Briones, Cory Yamashita, Lior Dolgonos, Jan Sap

Am J Pathol· May 2014

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A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation.
Malene Ambjørn, Véronique Dubreuil, Federico Miozzo, Fabienne Nigon, Bente Møller, Jan Sap

PLoS One· January 2014

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Low-density lipoprotein receptor-related protein-1 (LRP1) mediates autophagy and apoptosis caused by Helicobacter pylori VacA.
Kinnosuke Yahiro, Mamoru Satoh, Masayuki Nakano, Junzo Hisatsune, Hajime Isomoto, Jan Sap

J Biol Chem· September 2012

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Loss of function studies in mice and genetic association link receptor protein tyrosine phosphatase α to schizophrenia.
Nagahide Takahashi, Karin Sandager Nielsen, Branko Aleksic, Steffen Petersen, Masashi Ikeda, Jan Sap

Biol Psychiatry· October 2011

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Regulatory effects of nitric oxide on Src kinase, FAK, p130Cas, and receptor protein tyrosine phosphatase alpha (PTP-alpha): a role for the cellular redox environment.
Marli F Curcio, Wagner L Batista, Edlaine Linares, Fabio D Nascimento, Miriam S Moraes, Jan Sap

Antioxid Redox Signal· July 2010

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Activation of c-Src and Fyn kinases by protein-tyrosine phosphatase RPTPalpha is substrate-specific and compatible with lipid raft localization.
Nathalie Vacaresse, Bente Møller, E Michael Danielsen, Masato Okada, Jan Sap

J Biol Chem· December 2008

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Genes contributing to prion pathogenesis.
Gültekin Tamgüney, Kurt Giles, David V Glidden, Pierre Lessard, Holger Wille, Jan Sap

J Gen Virol· July 2008

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Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kappaB activation.
Junzo Hisatsune, Masaaki Nakayama, Hajime Isomoto, Hisao Kurazono, Naofumi Mukaida, Jan Sap

J Immunol· April 2008

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RPTPalpha is required for rigidity-dependent inhibition of extension and differentiation of hippocampal neurons.
Ana Kostic, Jan Sap, Michael P Sheetz

J Cell Sci· November 2007

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Helicobacter pylori VacA enhances prostaglandin E2 production through induction of cyclooxygenase 2 expression via a p38 mitogen-activated protein kinase/activating transcription factor 2 cascade in AZ-521 cells.
Junzo Hisatsune, Eiki Yamasaki, Masaaki Nakayama, Daisuke Shirasaka, Hisao Kurazono, Jan Sap

Infect Immun· September 2007

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Clustering of Helicobacter pylori VacA in lipid rafts, mediated by its receptor, receptor-like protein tyrosine phosphatase beta, is required for intoxication in AZ-521 Cells.
Masaaki Nakayama, Jyunzo Hisatsune, Eiki Yamasaki, Yoshito Nishi, Akihiro Wada, Jan Sap

Infect Immun· December 2006

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Tyrosine phosphatases epsilon and alpha perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells.
Zohar Tiran, Asher Peretz, Tal Sines, Vera Shinder, Jan Sap

Mol Biol Cell· October 2006

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Essential domain of receptor tyrosine phosphatase beta (RPTPbeta) for interaction with Helicobacter pylori vacuolating cytotoxin.
Kinnosuke Yahiro, Akihiro Wada, Eiki Yamasaki, Masaaki Nakayama, Yoshito Nishi, Jan Sap

J Biol Chem· December 2004

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Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation.
Angiola Petrone, Fortunato Battaglia, Cheng Wang, Adina Dusa, Jing Su, Jan Sap

EMBO J· August 2003

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RPTP-alpha acts as a transducer of mechanical force on alphav/beta3-integrin-cytoskeleton linkages.
Gotz von Wichert, Guoying Jiang, Ana Kostic, Kurt De Vos, Jan Sap

J Cell Biol· April 2003

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The differentiation of skeletal muscle cells involves a protein-tyrosine phosphatase-alpha-mediated C-Src signaling pathway.
Huogen Lu, Poonam Shah, David Ennis, Gail Shinder, Jan Sap

J Biol Chem· November 2002

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c-SRC mediates neurite outgrowth through recruitment of Crk to the scaffolding protein Sin/Efs without altering the kinetics of ERK activation.
Liang-Tung Yang, Konstantina Alexandropoulos, Jan Sap

J Biol Chem· May 2002

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