Publications by authors named "Janek Walker"

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Integrated genomics with refined cell-of-origin subtyping distinguishes subtype-specific mechanisms of treatment resistance and relapse in diffuse large B-cell lymphoma.
Janek S Walker, Kerstin Wenzl, Joseph P Novak, Matthew E Stokes, Melissa A Hopper

Blood Cancer J· July 2025

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DEK regulates B-cell proliferative capacity and is associated with aggressive disease in low-grade B-cell lymphomas.
Melissa A Hopper, Abigail R Dropik, Janek S Walker, Joseph P Novak, Miranda S Laverty

Blood Cancer J· October 2024

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Multiomic analysis identifies a high-risk signature that predicts early clinical failure in DLBCL.
Kerstin Wenzl, Matthew E Stokes, Joseph P Novak, Allison M Bock, Sana Khan, Janek S Walker

Blood Cancer J· June 2024

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Multiomic Analysis Identifies a High-Risk Metabolic and TME Depleted Signature that Predicts Early Clinical Failure in DLBCL.
Kerstin Wenzl, Matt Stokes, Joseph P Novak, Allison M Bock, Sana Khan, Janek S Walker

medRxiv· June 2023

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VIP152 is a selective CDK9 inhibitor with pre-clinical in vitro and in vivo efficacy in chronic lymphocytic leukemia.
Steven Sher, Ethan Whipp, Janek Walker, Pu Zhang, Larry Beaver, Brandi Walker

Leukemia· February 2023

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Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter's transformation.
Zachary A Hing, Janek S Walker, Ethan C Whipp, Lindsey Brinton, Matthew Cannon

Nat Commun· January 2023

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Targeting OXPHOS de novo purine synthesis as the nexus of inhibitor-mediated synergistic antileukemic actions.
Pu Zhang, Lindsey T Brinton, Mehdi Gharghabi, Steven Sher, Katie Williams, Janek S Walker

Sci Adv· September 2022

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Selinexor Combined with Ibrutinib Demonstrates Tolerability and Safety in Advanced B-Cell Malignancies: A Phase I Study.
Deborah M Stephens, Ying Huang, Amy S Ruppert, Janek S Walker, Daniel Canfield

Clin Cancer Res· August 2022

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Rare t(X;14)(q28;q32) translocation reveals link between MTCP1 and chronic lymphocytic leukemia.
Janek S Walker, Zachary A Hing, Steven Sher, James Cronin, Katie Williams, Brandi R Walker

Nat Commun· November 2021

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Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
Janek S Walker, Zachary A Hing, Bonnie Harrington, Jordan Baumhardt, Hatice Gulcin Ozer

J Hematol Oncol· January 2021

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Selinexor for advanced hematologic malignancies.
Janek S Walker, Ramiro Garzon, Rosa Lapalombella

Leuk Lymphoma· October 2020

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Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Jordan M Baumhardt, Janek S Walker, Yoonji Lee, Binita Shakya, Chad A Brautigam

Mol Biol Cell· August 2020

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