Publications by authors named "Larry Beaver"

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Small amounts of misassembly can have disproportionate effects on pangenome-based metagenomic analyses.
Stephanie N Majernik, Larry Beaver, Patrick H Bradley

mSphere· May 2025

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Small amounts of misassembly can have disproportionate effects on pangenome-based metagenomic analyses.
Stephanie N Majernik, Larry Beaver, Patrick H Bradley

bioRxiv· October 2024

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VIP152 is a selective CDK9 inhibitor with pre-clinical in vitro and in vivo efficacy in chronic lymphocytic leukemia.
Steven Sher, Ethan Whipp, Janek Walker, Pu Zhang, Larry Beaver

Leukemia· February 2023

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Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter's transformation.
Zachary A Hing, Janek S Walker, Ethan C Whipp, Lindsey Brinton, Matthew Cannon, Larry P Beaver

Nat Commun· January 2023

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Targeting OXPHOS de novo purine synthesis as the nexus of inhibitor-mediated synergistic antileukemic actions.
Pu Zhang, Lindsey T Brinton, Mehdi Gharghabi, Steven Sher, Katie Williams, Larry Beaver

Sci Adv· September 2022

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DNA Origami Nanostructures Elicit Dose-Dependent Immunogenicity and Are Nontoxic up to High Doses In Vivo.
Christopher R Lucas, Patrick D Halley, Amjad A Chowdury, Bonnie K Harrington, Larry Beaver

Small· July 2022

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PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia.
Swagata Goswami, Rajeswaran Mani, Jessica Nunes, Chi-Ling Chiang, Kevan Zapolnik, Larry Beaver

Blood· March 2022

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Rare t(X;14)(q28;q32) translocation reveals link between MTCP1 and chronic lymphocytic leukemia.
Janek S Walker, Zachary A Hing, Steven Sher, James Cronin, Katie Williams, Larry P Beaver

Nat Commun· November 2021

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Anti-tumor NAMPT inhibitor, KPT-9274, mediates gender-dependent murine anemia and nephrotoxicity by regulating SIRT3-mediated SOD deacetylation.
Shaneice Mitchell, Pu Zhang, Matthew Cannon, Larry Beaver, Amy Lehman

J Hematol Oncol· June 2021

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Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition.
Pu Zhang, Lindsey T Brinton, Katie Williams, Steven Sher, Shelley Orwick, Larry Beaver

Clin Cancer Res· April 2021

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Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
Janek S Walker, Zachary A Hing, Bonnie Harrington, Jordan Baumhardt, Hatice Gulcin Ozer, Larry Beaver

J Hematol Oncol· January 2021

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Synergistic effect of BCL2 and FLT3 co-inhibition in acute myeloid leukemia.
Lindsey T Brinton, Pu Zhang, Katie Williams, Daniel Canfield, Shelley Orwick, Larry Beaver

J Hematol Oncol· October 2020

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Coordinated inhibition of nuclear export and Bcr-Abl1 selectively targets chronic myeloid leukemia stem cells.
Hein Than, Anthony D Pomicter, Dongqing Yan, Larry P Beaver, Anna M Eiring

Leukemia· June 2020

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Leukemic B Cell CTLA-4 Suppresses Costimulation of T Cells.
Priscilla Do, Kyle A Beckwith, Carolyn Cheney, Minh Tran, Larry Beaver

J Immunol· May 2019

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Selective targeting of NAMPT by KPT-9274 in acute myeloid leukemia.
Shaneice R Mitchell, Karilyn Larkin, Nicole R Grieselhuber, Tzung-Huei Lai, Matthew Cannon, Larry Beaver

Blood Adv· February 2019

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BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor.
Hatice Gulcin Ozer, Dalia El-Gamal, Ben Powell, Zachary A Hing, James S Blachly, Larry Beaver

Cancer Discov· April 2018

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