Publications by authors named "Janetta Dewhurst"

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Discovery and Optimization of First-in-Class Molecular Glue Degraders of the WIZ Transcription Factor for Fetal Hemoglobin Induction to Treat Sickle Cell Disease.
John Ryan Kerrigan, Noel M Thomsen, Artiom Cernijenko, Sarah E Kochanek, Janetta Dewhurst

J Med Chem· November 2024

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Discovery of LFF571: an investigational agent for Clostridium difficile infection.
Matthew J LaMarche, Jennifer A Leeds, Adam Amaral, Jason T Brewer, Simon M Bushell, Janetta M Dewhurst

J Med Chem· March 2012

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Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids.
Matthew J LaMarche, Jennifer A Leeds, Kerri Amaral, Jason T Brewer, Simon M Bushell, Janetta M Dewhurst

J Med Chem· December 2011

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Atomic-scale characterization of conformational changes in the preQ₁ riboswitch aptamer upon ligand binding.
Paula M Petrone, Janetta Dewhurst, Ruben Tommasi, Lewis Whitehead, Andrea K Pomerantz

J Mol Graph Model· September 2011

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Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV).
Aurelio Bonavia, Michael Franti, Erin Pusateri Keaney, Kelli Kuhen, Mohindra Seepersaud, Janetta Dewhurst

Proc Natl Acad Sci U S A· April 2011

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