Publications by authors named "Janette Sutton"

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Constitutive Turbodomains enhance expansion and antitumor activity of allogeneic BCMA CAR T cells in preclinical models.
Regina J Lin, Janette Sutton, Trevor Bentley, Diego A Vargas-Inchaustegui, Duy Nguyen

Sci Adv· August 2023

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Allogeneic CAR T Cells Targeting DLL3 Are Efficacious and Safe in Preclinical Models of Small Cell Lung Cancer.
Yi Zhang, Silvia K Tacheva-Grigorova, Janette Sutton, Zea Melton, Yvonne S L Mak

Clin Cancer Res· March 2023

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Design and Validation of Inducible TurboCARs with Tunable Induction and Combinatorial Cytokine Signaling.
Regina J Lin, Andrew R Nager, Spencer Park, Janette Sutton, Cecilia Lay

Cancer Immunol Res· September 2022

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Allogeneic FLT3 CAR T Cells with an Off-Switch Exhibit Potent Activity against AML and Can Be Depleted to Expedite Bone Marrow Recovery.
Cesar Sommer, Hsin-Yuan Cheng, Duy Nguyen, Danielle Dettling, Yik Andy Yeung, Janette Sutton

Mol Ther· October 2020

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Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma.
Cesar Sommer, Bijan Boldajipour, Tracy C Kuo, Trevor Bentley, Janette Sutton

Mol Ther· June 2019

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Improved Lysosomal Trafficking Can Modulate the Potency of Antibody Drug Conjugates.
Rachel M DeVay, Kathy Delaria, Guoyun Zhu, Charles Holz, Davide Foletti, Janette Sutton

Bioconjug Chem· April 2017

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Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy.
Magdalena Dorywalska, Pavel Strop, Jody A Melton-Witt, Adela Hasa-Moreno, Santiago E Farias, Janette Sutton

PLoS One· April 2016

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Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading.
Pavel Strop, Kathy Delaria, Davide Foletti, Jody Melton Witt, Adela Hasa-Moreno, Janette Sutton

Nat Biotechnol· July 2015

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Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair.
Pavel Strop, Wei-Hsien Ho, Leila M Boustany, Yasmina N Abdiche, Kevin C Lindquist, Janette Sutton

J Mol Biol· July 2012

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Increasing serum half-life and extending cholesterol lowering in vivo by engineering antibody with pH-sensitive binding to PCSK9.
Javier Chaparro-Riggers, Hong Liang, Rachel M DeVay, Lanfang Bai, Janette E Sutton

J Biol Chem· March 2012

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Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates.
Hong Liang, Javier Chaparro-Riggers, Pavel Strop, Tao Geng, Janette E Sutton

J Pharmacol Exp Ther· February 2012

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Involvement of the neurotensin receptor 1 in the behavioral effects of two neurotensin agonists, NT-2 and NT69L: lack of hypothermic, antinociceptive and antipsychotic actions in receptor knockout mice.
Jordan A Mechanic, Janette E Sutton, Amy E Berson, Xiaosu Wu, Joyce Kwan

Eur Neuropsychopharmacol· July 2009

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