Publications by authors named "Kathy Delaria"

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Design and Characterization of 4D-710, an Aerosolized Gene Therapy for Cystic Fibrosis Lung Disease.
Melissa A Calton, Roxanne H Croze, Theodore H Sullivan, Sara A Collins, Sarah Tucker, Kathy Delaria

Am J Respir Cell Mol Biol· October 2025

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Preclinical Efficacy and Safety Comparison of CD3 Bispecific and ADC Modalities Targeting BCMA for the Treatment of Multiple Myeloma.
Siler H Panowski, Tracy C Kuo, Yi Zhang, Amy Chen, Tao Geng, Kathy Delaria

Mol Cancer Ther· November 2019

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Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates.
Maria José Costa, Jyothirmayee Kudaravalli, Jing-Tyan Ma, Wei-Hsien Ho, Kathy Delaria

Sci Rep· February 2019

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Improved Lysosomal Trafficking Can Modulate the Potency of Antibody Drug Conjugates.
Rachel M DeVay, Kathy Delaria, Guoyun Zhu, Charles Holz, Davide Foletti

Bioconjug Chem· April 2017

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RN927C, a Site-Specific Trop-2 Antibody-Drug Conjugate (ADC) with Enhanced Stability, Is Highly Efficacious in Preclinical Solid Tumor Models.
Pavel Strop, Thomas-Toan Tran, Magdalena Dorywalska, Kathy Delaria, Russell Dushin

Mol Cancer Ther· November 2016

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Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design.
Magdalena Dorywalska, Russell Dushin, Ludivine Moine, Santiago E Farias, Dahui Zhou, Kathy Delaria

Mol Cancer Ther· May 2016

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Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy.
Magdalena Dorywalska, Pavel Strop, Jody A Melton-Witt, Adela Hasa-Moreno, Santiago E Farias, Kathy Delaria

PLoS One· April 2016

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Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading.
Pavel Strop, Kathy Delaria, Davide Foletti, Jody Melton Witt, Adela Hasa-Moreno

Nat Biotechnol· July 2015

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Effect of attachment site on stability of cleavable antibody drug conjugates.
Magdalena Dorywalska, Pavel Strop, Jody A Melton-Witt, Adela Hasa-Moreno, Santiago E Farias, Kathy Delaria

Bioconjug Chem· April 2015

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Mass spectrometric characterization of transglutaminase based site-specific antibody-drug conjugates.
Santiago E Farias, Pavel Strop, Kathy Delaria, Meritxell Galindo Casas, Magdalena Dorywalska

Bioconjug Chem· February 2014

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Location matters: site of conjugation modulates stability and pharmacokinetics of antibody drug conjugates.
Pavel Strop, Shu-Hui Liu, Magdalena Dorywalska, Kathy Delaria, Russell G Dushin

Chem Biol· February 2013

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Comparison of competitive ligand-binding assay and bioassay formats for the measurement of neutralizing antibodies to protein therapeutics.
Deborah Finco, Daniel Baltrukonis, Adrienne Clements-Egan, Kathy Delaria, George R Gunn

J Pharm Biomed Anal· January 2011

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