Publications by authors named "Jared Lucas"

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Multiomic assessments of LNCaP and derived cell strains reveal determinants of prostate cancer pathobiology.
Arnab Bose, Armand Bankhead, Ilsa Coleman, Thomas Persse, Wanting Han, Jared Lucas

J Clin Invest· November 2025

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Supraphysiological Androgens Promote the Tumor Suppressive Activity of the Androgen Receptor through cMYC Repression and Recruitment of the DREAM Complex.
Michael D Nyquist, Ilsa M Coleman, Jared M Lucas, Dapei Li, Brian Hanratty

Cancer Res· September 2023

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Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes.
Navonil De Sarkar, Robert D Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Jared M Lucas

Cancer Discov· March 2023

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Comprehensive assessment of anaplastic lymphoma kinase in localized and metastatic prostate cancer reveals targetable alterations.
Radhika A Patel, Ilsa Coleman, Martine P Roudier, Eric Q Konnick, Brian Hanratty, Jared M Lucas

Cancer Res Commun· May 2022

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Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer.
Navonil De Sarkar, Sayan Dasgupta, Payel Chatterjee, Ilsa Coleman, Gavin Ha, Jared M Lucas

JCI Insight· December 2021

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BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program.
Dae-Hwan Kim, Duanchen Sun, William K Storck, Katherine Welker Leng, Chelsea Jenkins, Jared M Lucas

Clin Cancer Res· September 2021

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For Us, COVID-19 Is Personal.
Janice Blanchard, Tenagne Haile-Mariam, Natasha N Powell, Aisha Terry, Malika Fair, Jared Lucas

Acad Emerg Med· July 2020

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Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress.
Michael D Nyquist, Alexandra Corella, Ilsa Coleman, Navonil De Sarkar, Arja Kaipainen, Jared Lucas

Cell Rep· May 2020

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Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer.
Alexandra N Corella, Ma Victoria Andrea Cabiliza Ordonio, Ilsa Coleman, Jared M Lucas, Arja Kaipainen

Clin Cancer Res· April 2020

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Molecular determinants of response to high-dose androgen therapy in prostate cancer.
Michael D Nyquist, Alexandra Corella, Osama Mohamad, Ilsa Coleman, Arja Kaipainen, Jared M Lucas

JCI Insight· October 2019

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Testosterone accumulation in prostate cancer cells is enhanced by facilitated diffusion.
Arja Kaipainen, Ailin Zhang, Rui M Gil da Costa, Jared Lucas, Brett Marck

Prostate· September 2019

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Supraphysiological androgens suppress prostate cancer growth through androgen receptor-mediated DNA damage.
Payel Chatterjee, Michael T Schweizer, Jared M Lucas, Ilsa Coleman, Michael D Nyquist

J Clin Invest· July 2019

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Acute liver failure and emergency consideration for liver transplant.
Hamid Shokoohi, Ali Pourmand, Jason Teng, Jared Lucas

Am J Emerg Med· November 2017

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Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling.
Eric G Bluemn, Ilsa M Coleman, Jared M Lucas, Roger T Coleman, Susana Hernandez-Lopez

Cancer Cell· October 2017

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A proteolytic modification of AIM promotes its renal excretion.
Tomoko Yamazaki, Ryoichi Sugisawa, Emiri Hiramoto, Ryosuke Takai, Ayaka Matsumoto, Jared M Lucas

Sci Rep· December 2016

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Long non-coding RNA: A newly deciphered "code" in prostate cancer.
Ailin Zhang, Jiawei Zhang, Arja Kaipainen, Jared M Lucas, Hong Yang

Cancer Lett· June 2016

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Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer.
Akash Kumar, Ilsa Coleman, Colm Morrissey, Xiaotun Zhang, Lawrence D True, Jared M Lucas

Nat Med· April 2016

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Chemotherapy-induced monoamine oxidase expression in prostate carcinoma functions as a cytoprotective resistance enzyme and associates with clinical outcomes.
Ryan R Gordon, Mengchu Wu, Chung-Ying Huang, William P Harris, Hong Gee Sim, Jared M Lucas

PLoS One· November 2015

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SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer.
Xiaotun Zhang, Ilsa M Coleman, Lisha G Brown, Lawrence D True, Lori Kollath, Jared M Lucas

Clin Cancer Res· October 2015

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ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.
Liem T Nguyen, Maria S Tretiakova, Mark R Silvis, Jared Lucas, Olga Klezovitch

Cancer Cell· June 2015

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DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance.
Roland M Huber, Jared M Lucas, Luis A Gomez-Sarosi, Ilsa Coleman, Song Zhao

Oncotarget· February 2015

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The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.
Jared M Lucas, Cynthia Heinlein, Tom Kim, Susana A Hernandez, Muzdah S Malik

Cancer Discov· November 2014

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Setting wait times to achieve targeted left-without-being-seen rates.
Jared Lucas, Robert J Batt, Olanrewaju A Soremekun

Am J Emerg Med· April 2014

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Prognostic value of ERG oncoprotein in prostate cancer recurrence and cause-specific mortality.
E Sophie Spencer, Richard B Johnston, Ryan R Gordon, Jared M Lucas, Cigdem Himmetoglu Ussakli

Prostate· June 2013

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Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts.
Stephanie Bertram, Adeline Heurich, Hayley Lavender, Stefanie Gierer, Simon Danisch, Jared M Lucas

PLoS One· September 2012

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