Publications by authors named "Jared Silverman"

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Strategies for shortening tuberculosis therapy.
Véronique A Dartois, Valerie Mizrahi, Radojka M Savic, Jared A Silverman, David Hermann

Nat Med· June 2025

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Comparing the efficacy in reducing brain injury of different neuroprotective agents following neonatal hypoxia-ischemia in newborn rats: a multi-drug randomized controlled screening trial.
Hemmen Sabir, Elke Maes, Margit Zweyer, Yvonne Schleehuber, Farhad B Imam, Jared Silverman

Sci Rep· June 2023

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Randomized Study of Rivaroxaban vs Placebo on Disease Progression and Symptoms Resolution in High-Risk Adults With Mild Coronavirus Disease 2019.
Jintanat Ananworanich, Robin Mogg, Michael W Dunne, Mohamed Bassyouni, Consuela Vera David, Jared Silverman

Clin Infect Dis· August 2022

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Perspective on Antibacterial Lead Identification Challenges and the Role of Hypothesis-Driven Strategies.
Laura L McDowell, Cheryl L Quinn, Jennifer A Leeds, Jared A Silverman, Lynn L Silver

SLAS Discov· April 2019

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Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design.
Jason B Cross, Jing Zhang, Qingyi Yang, Michael F Mesleh, Jan Antoinette C Romero, Jared Silverman

ACS Med Chem Lett· April 2016

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Discovery and development of surotomycin for the treatment of Clostridium difficile.
Victoria Knight-Connoni, Carmela Mascio, Laurent Chesnel, Jared Silverman

J Ind Microbiol Biotechnol· March 2016

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Alternatives to antibiotics-a pipeline portfolio review.
Lloyd Czaplewski, Richard Bax, Martha Clokie, Mike Dawson, Heather Fairhead, Jared Silverman

Lancet Infect Dis· February 2016

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Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
Jing Zhang, Qingyi Yang, Jason B Cross, Jan Antoinette C Romero, Katherine M Poutsiaka, Jared Silverman

J Med Chem· November 2015

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Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Jing Zhang, Qingyi Yang, Jan Antoinette C Romero, Jason Cross, Bin Wang, Jared Silverman

ACS Med Chem Lett· October 2015

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Structure-Activity Relationship Studies of a Series of Semisynthetic Lipopeptides Leading to the Discovery of Surotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatment of Clostridium difficile-Associated Diarrhea.
Ning Yin, Jing Li, Yong He, Prudencio Herradura, Andre Pearson, Jared Silverman

J Med Chem· June 2015

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Daptomycin forms cation- and size-selective pores in model membranes.
TianHua Zhang, Jawad K Muraih, Ben MacCormick, Jared Silverman, Michael Palmer

Biochim Biophys Acta· October 2014

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Surotomycin demonstrates low in vitro frequency of resistance and rapid bactericidal activity in Clostridium difficile, Enterococcus faecalis, and Enterococcus faecium.
Carmela T M Mascio, Laurent Chesnel, Grace Thorne, Jared A Silverman

Antimicrob Agents Chemother· July 2014

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Cardiolipin prevents membrane translocation and permeabilization by daptomycin.
TianHua Zhang, Jawad K Muraih, Nasim Tishbi, Jennifer Herskowitz, Rachel L Victor, Jared Silverman

J Biol Chem· April 2014

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Additional routes to Staphylococcus aureus daptomycin resistance as revealed by comparative genome sequencing, transcriptional profiling, and phenotypic studies.
Yang Song, Aileen Rubio, Radheshyam K Jayaswal, Jared A Silverman, Brian J Wilkinson

PLoS One· September 2013

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Mutual inhibition through hybrid oligomer formation of daptomycin and the semisynthetic lipopeptide antibiotic CB-182,462.
Tianhua Zhang, Jawad K Muraih, Evan Mintzer, Nasim Tishbi, Celine Desert, Jared Silverman

Biochim Biophys Acta· February 2013

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In vitro and in vivo characterization of CB-183,315, a novel lipopeptide antibiotic for treatment of Clostridium difficile.
Carmela T M Mascio, Lawrence I Mortin, Karen T Howland, Andrew D G Van Praagh, Shuxin Zhang, Jared A Silverman

Antimicrob Agents Chemother· October 2012

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Reduced pulmonary surfactant interaction of daptomycin analogs via tryptophan replacement with alternative amino acids.
Yong He, Jing Li, Nin Yin, Prudencio S Herradura, Larry Martel, Jared A Silverman

Bioorg Med Chem Lett· October 2012

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Daptomycin-mediated reorganization of membrane architecture causes mislocalization of essential cell division proteins.
Joe Pogliano, Nicolas Pogliano, Jared A Silverman

J Bacteriol· September 2012

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Cellular architecture mediates DivIVA ultrastructure and regulates min activity in Bacillus subtilis.
Prahathees Eswaramoorthy, Marcella L Erb, James A Gregory, Jared Silverman, Kit Pogliano

mBio· March 2012

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LC-MS/MS characterization of phospholipid content in daptomycin-susceptible and -resistant isolates of Staphylococcus aureus with mutations in mprF.
Aileen Rubio, Jeff Moore, Mustafa Varoglu, Mary Conrad, Min Chu, Jared A Silverman

Mol Membr Biol· February 2012

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VraSR two-component regulatory system contributes to mprF-mediated decreased susceptibility to daptomycin in in vivo-selected clinical strains of methicillin-resistant Staphylococcus aureus.
Shrenik Mehta, Arabela X Cuirolo, Konrad B Plata, Sarah Riosa, Jared A Silverman

Antimicrob Agents Chemother· January 2012

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Genetic basis for daptomycin resistance in enterococci.
Kelli L Palmer, Anu Daniel, Crystal Hardy, Jared Silverman, Michael S Gilmore

Antimicrob Agents Chemother· July 2011

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Evaluating the activity of the RNA polymerase inhibitor myxopyronin B against Staphylococcus aureus.
Terence I Moy, Anu Daniel, Crystal Hardy, Andrew Jackson, Owen Rehrauer, Jared A Silverman

FEMS Microbiol Lett· June 2011

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Oligomerization of daptomycin on membranes.
Jawad K Muraih, Andre Pearson, Jared Silverman, Michael Palmer

Biochim Biophys Acta· April 2011

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Regulation of mprF by antisense RNA restores daptomycin susceptibility to daptomycin-resistant isolates of Staphylococcus aureus.
Aileen Rubio, Mary Conrad, Robert J Haselbeck, Kedar G C, Vickie Brown-Driver, Jared A Silverman

Antimicrob Agents Chemother· January 2011

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