Publications by authors named "Jason A Hackney"

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Comprehensive profiling of the human fecal proteome from IBD patients with DIA-MS enables evaluation of disease-relevant proteins.
Brandon J Harder, Annemarie N Lekkerkerker, Ellen P Casavant, Jason A Hackney, Allen Nguyen

Proteomics Clin Appl· September 2024

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Author Correction: c-Maf-dependent T cell control of intestinal T17 cells and IgA establishes host-microbiota homeostasis.
Christian Neumann, Jonas Blume, Urmi Roy, Peggy P Teh, Ajithkumar Vasanthakumar, Jason A Hackney

Nat Immunol· July 2024

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A targeted amplicon next-generation sequencing assay for tryptase genotyping to support personalized therapy in mast cell-related disorders.
Olga Li, Jason A Hackney, David F Choy, Diana Chang, Rhea Nersesian

PLoS One· February 2024

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Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain type 2 immunity.
Riccardo Guidi, Christopher Wedeles, Daqi Xu, Krzysztof Kolmus, Sarah E Headland, Jason A Hackney

Cell Rep· December 2023

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A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling.
Jason A Hackney, Haridha Shivram, Jason Vander Heiden, Chris Overall, Luz Orozco

iScience· October 2023

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Transcriptomic and proteomic assessment of tocilizumab response in a randomized controlled trial of patients hospitalized with COVID-19.
Haridha Shivram, Jason A Hackney, Carrie M Rosenberger, Anastasia Teterina, Aditi Qamra

iScience· September 2023

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An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases.
Markus M Xie, Bingbing Dai, Jason A Hackney, Tianhe Sun, Juan Zhang

Cell Rep Med· August 2023

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Myeloid cell influx into the colonic epithelium is associated with disease severity and non-response to anti-Tumor Necrosis Factor Therapy in patients with Ulcerative Colitis.
Divya Jha, Zainab Al-Taie, Azra Krek, Shadi Toghi Eshghi, Aurelie Fantou, Jason A Hackney

bioRxiv· June 2023

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Obligate role for Rock1 and Rock2 in adult stem cell viability and function.
Arivazhagan Sambandam, Elaine Storm, Helen Tauc, Jason A Hackney, David Garfield

Heliyon· March 2023

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Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration.
Luz D Orozco, Hsu-Hsin Chen, Christian Cox, Kenneth J Katschke, Rommel Arceo, Jason A Hackney

Cell Rep· March 2023

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Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
Joseph Chavarria-Smith, Cecilia P C Chiu, Janet K Jackman, Jianping Yin, Juan Zhang, Jason A Hackney

Sci Transl Med· December 2022

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Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity.
Mathieu Uzzan, Jerome C Martin, Luka Mesin, Alexandra E Livanos, Tomas Castro-Dopico, Jason A Hackney

Nat Med· April 2022

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Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease.
Mary E Keir, Franklin Fuh, Ryan Ichikawa, Meghan Acres, Jason A Hackney

J Immunol· November 2021

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Efficacy, Safety, and Pharmacodynamic Effects of the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib (GDC-0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double-Blind, Placebo-Controlled Trial.
David Isenberg, Richard Furie, Nicholas S Jones, Pascal Guibord, Joshua Galanter, Jason A Hackney

Arthritis Rheumatol· October 2021

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Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease.
Bingbing Dai, Jason A Hackney, Ryan Ichikawa, Allen Nguyen, Justin Elstrott

Cell Rep Med· August 2021

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Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells.
Helen M Tauc, Imilce A Rodriguez-Fernandez, Jason A Hackney, Michal Pawlak, Tal Ronnen Oron

Elife· March 2021

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Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage.
Andrew P AhYoung, Sterling C Eckard, Alvin Gogineni, Hongkang Xi, S Jack Lin, Jason A Hackney

Commun Biol· November 2020

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The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells.
Cesar A Corzo, Eugene Varfolomeev, A Francesca Setiadi, Ross Francis, Sha Klabunde, Jason A Hackney

Sci Signal· June 2020

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Fenebrutinib versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double-Blind, Phase II Trial (ANDES Study).
Stanley Cohen, Katie Tuckwell, Tamiko R Katsumoto, Rui Zhao, Joshua Galanter, Jason A Hackney

Arthritis Rheumatol· April 2020

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An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Henry R Maun, Janet K Jackman, David F Choy, Kelly M Loyet, Tracy L Staton, Jason A Hackney

Cell· January 2020

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Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration.
Luz D Orozco, Hsu-Hsin Chen, Christian Cox, Kenneth J Katschke, Rommel Arceo, Jason A Hackney

Cell Rep· January 2020

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Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC).
Gloria Lliso-Ribera, Frances Humby, Myles Lewis, Alessandra Nerviani, Daniele Mauro, Jason A Hackney

Ann Rheum Dis· December 2019

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An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Henry R Maun, Janet K Jackman, David F Choy, Kelly M Loyet, Tracy L Staton, Jason A Hackney

Cell· October 2019

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Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes.
Myles J Lewis, Michael R Barnes, Kevin Blighe, Katriona Goldmann, Sharmila Rana, Jason A Hackney

Cell Rep· August 2019

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Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients.
Frances Humby, Myles Lewis, Nandhini Ramamoorthi, Jason A Hackney, Michael R Barnes

Ann Rheum Dis· June 2019

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