Publications by authors named "Jason D Berndt"

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A multivariate cell-based liquid biopsy for lung nodule risk stratification: Analytical validation and early clinical evaluation.
Jason D Berndt, Fergal J Duffy, Mark D D'Ascenzo, Leslie R Miller, Yijun Qi

J Liq Biopsy· September 2025

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An Indicator Cell Assay-based Multivariate Blood Test for Early Detection of Alzheimer's Disease.
Yijun Sherry Qi, Leslie Rae Miller, Mark D D'Ascenzo, Jason D Berndt, G Adam Whitney

medRxiv· September 2025

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A multivariate cell-based assay for blood-based diagnostics enhances lung cancer risk stratification.
Jason D Berndt, Fergal J Duffy, Mark D D'Ascenzo, Leslie R Miller, Yijun Qi

medRxiv· April 2025

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A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics.
Elizabeth M Steenkiste, Jason D Berndt, Carissa Pilling, Christopher Simpkins, Jonathan A Cooper

Elife· June 2021

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Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish.
Jeremy S Rabinowitz, Aaron M Robitaille, Yuliang Wang, Catherine A Ray, Ryan Thummel, Jason D Berndt

Proc Natl Acad Sci U S A· January 2017

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Wnt/β-catenin signaling promotes self-renewal and inhibits the primed state transition in naïve human embryonic stem cells.
Zhuojin Xu, Aaron M Robitaille, Jason D Berndt, Kathryn C Davidson, Karin A Fischer

Proc Natl Acad Sci U S A· October 2016

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Wnt/β-catenin signaling promotes regeneration after adult zebrafish spinal cord injury.
Nicholas S Strand, Kimberly K Hoi, Tien M T Phan, Catherine A Ray, Jason D Berndt

Biochem Biophys Res Commun· September 2016

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USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds.
Babita Madan, Matthew P Walker, Robert Young, Laura Quick, Kelly A Orgel, Jason D Berndt

Proc Natl Acad Sci U S A· May 2016

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The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice.
Adriana Forero, Jennifer Tisoncik-Go, Tokiko Watanabe, Gongxun Zhong, Masato Hatta, Jason D Berndt

J Virol· December 2015

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2014: signaling breakthroughs of the year.
Jason D Berndt, Wei Wong

Sci Signal· January 2015

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FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells.
Willliam Conrad, Michael B Major, Michele A Cleary, Marc Ferrer, Brian Roberts, Jason D Berndt

F1000Res· February 2014

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2013: Signaling breakthroughs of the year.
Jason D Berndt, Nancy R Gough

Sci Signal· January 2014

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Simvastatin promotes adult hippocampal neurogenesis by enhancing Wnt/β-catenin signaling.
Nicholas C Robin, Zsuzsa Agoston, Travis L Biechele, Richard G James, Jason D Berndt

Stem Cell Reports· January 2014

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Protein kinase PKN1 represses Wnt/β-catenin signaling in human melanoma cells.
Richard G James, Katherine A Bosch, Rima M Kulikauskas, Peitzu T Yang, Nick C Robin, Jason D Berndt

J Biol Chem· November 2013

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Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS).
Olena Korvatska, Nicholas S Strand, Jason D Berndt, Tim Strovas, Dong-Hui Chen

Hum Mol Genet· August 2013

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Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4.
Kathryn C Davidson, Allison M Adams, Jamie M Goodson, Circe E McDonald, Jennifer C Potter, Jason D Berndt

Proc Natl Acad Sci U S A· March 2012

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Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.
Jason D Berndt, Atsushi Aoyagi, Peitzu Yang, Jamie N Anastas, Lan Tang

J Cell Biol· September 2011

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A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling.
Richard A Klinghoffer, Jason Frazier, James Annis, Jason D Berndt, Brian S Roberts

PLoS One· September 2009

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Integrative analysis of genome-wide RNA interference screens.
Jason D Berndt, Travis L Biechele, Randall T Moon, Michael B Major

Sci Signal· May 2009

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Beta-catenin gets jaded and von Hippel-Lindau is to blame.
Jason D Berndt, Randall T Moon, Michael B Major

Trends Biochem Sci· March 2009

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Rho-kinase and myosin II affect dynamic neural crest cell behaviors during epithelial to mesenchymal transition in vivo.
Jason D Berndt, Matthew R Clay, Tobias Langenberg, Mary C Halloran

Dev Biol· December 2008

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New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening.
Michael B Major, Brian S Roberts, Jason D Berndt, Shane Marine, Jamie Anastas

Sci Signal· November 2008

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Crystal structure of a full-length beta-catenin.
Yi Xing, Ken-Ichi Takemaru, Jing Liu, Jason D Berndt, Jie J Zheng

Structure· March 2008

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Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.
Michael B Major, Nathan D Camp, Jason D Berndt, Xianhua Yi, Seth J Goldenberg

Science· May 2007

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Semaphorin 3d promotes cell proliferation and neural crest cell development downstream of TCF in the zebrafish hindbrain.
Jason D Berndt, Mary C Halloran

Development· October 2006

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