Publications by authors named "Jason D Shields"

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Synthetic chemistry enabling the discovery and development of a series of pyrazoles as HPK1 inhibitors.
Anthony J Metrano, Lucas A Morrill, Gayathri Bommakanti, Robert Casella, Steve Cook, Jason D Shields

RSC Med Chem· May 2025

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Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor.
Jason D Shields, David Baker, Amber Y S Balazs, Gayathri Bommakanti, Robert Casella

J Med Chem· February 2025

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Design and Synthesis of Acyclic Boronic Acid Arginase Inhibitors.
Jason D Shields, Brian M Aquila, David Emmons, M Raymond V Finlay, Eric T Gangl

J Med Chem· December 2024

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Discovery of (2,4)-4-(()-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.
Scott N Mlynarski, Brian M Aquila, Susan Cantin, Steve Cook, Aatman Doshi, Jason D Shields

J Med Chem· December 2024

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AiZynth impact on medicinal chemistry practice at AstraZeneca.
Jason D Shields, Rachel Howells, Gillian Lamont, Yin Leilei, Andrew Madin

RSC Med Chem· April 2024

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A modular, air-stable nickel precatalyst.
Jason D Shields, Erin E Gray, Abigail G Doyle

Org Lett· May 2015

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Enantioselective, nickel-catalyzed Suzuki cross-coupling of quinolinium ions.
Jason D Shields, Derek T Ahneman, Thomas J A Graham, Abigail G Doyle

Org Lett· January 2014

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Clickable Poly(ethylene glycol)-Microsphere-Based Cell Scaffolds.
Peter K Nguyen, Christopher G Snyder, Jason D Shields, Amanda W Smith, Donald L Elbert

Macromol Chem Phys· April 2013

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