Publications by authors named "Rachel Howells"

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Systematic review of paediatric SUDEP and epilepsy-related deaths to inform a safety counselling checklist for clinical practice.
Rohini Ranganath Rattihalli, Sammy Ashby, Lisa Burrows, Rachel Howells, Kezie Chukwudebelu

Seizure· September 2025

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Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome.
Avipsa Ghosh, Afshan Ahmed, Konstantina Amoiradaki, Amber Y S Balazs, Bernard Barlaam, Rachel Howells

J Med Chem· September 2025

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Development of a cannabis health literacy questionnaire: preliminary validation using the Rasch model.
Queen Jacques, Jennifer Donnan, Lisa Bishop, Rachel Howells, Zhiwei Gao

BMC Public Health· July 2025

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Exploring cannabis consumption stigma in Canada with consideration of age and gender differences.
Emily C Rowe, Ashlee R L Coles, Laura M Harris-Lane, Nick Harris, Lisa Bishop, Rachel Howells

Addict Behav Rep· June 2025

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Synthetic chemistry enabling the discovery and development of a series of pyrazoles as HPK1 inhibitors.
Anthony J Metrano, Lucas A Morrill, Gayathri Bommakanti, Robert Casella, Steve Cook, Rachel Howells

RSC Med Chem· May 2025

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Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor.
Jason D Shields, David Baker, Amber Y S Balazs, Gayathri Bommakanti, Robert Casella, Rachel Howells

J Med Chem· February 2025

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Post-Pandemic Engagement of Youth in Virtual Environments: Reflections and Lessons Learned From the Development of a Youth Education Program.
Jennifer Donnan, Rachel Howells, Dalainey H Drakes, Lisa D Bishop

J Early Adolesc· January 2025

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Bridging the gap: Exploring consumer experiences and motivations for transitioning between illicit and regulated cannabis markets.
Jennifer R Donnan, Rachel Howells, Sylvia Farooq, Myles Maillet, Laura M Harris-Lane

Int J Drug Policy· December 2024

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AiZynth impact on medicinal chemistry practice at AstraZeneca.
Jason D Shields, Rachel Howells, Gillian Lamont, Yin Leilei, Andrew Madin

RSC Med Chem· April 2024

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Management of migraine in children and adolescents.
Ishaq Abu-Arafeh, Rachel Howells

Handb Clin Neurol· February 2024

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The relationship between difficulties in the regulation of positive and negative emotions and binge-eating symptoms in young adults.
Rachel L Howells, Leigh C Dunn, Jacqueline C Carter

Eat Behav· January 2024

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NICE guideline review: Epilepsies in children, young people and adults NG217.
Katherine Elizabeth Anne Jones, Rachel Howells, Andrew A Mallick, Siba Prosad Paul, Indranil Dey

Arch Dis Child Educ Pract Ed· December 2023

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A narrative review of course evaluation methods for continuing professional development: The case of paediatric and neonatal acute-care in-service courses in low and lower-middle income countries: BEME Guide No. 76.
Alison Gifford, Rune Philemon, Jay Halbert, Eleanor J Hothersall, Rebecca Inglis, Rachel Howells

Med Teach· July 2023

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Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS with Demonstrable CNS Penetration.
Jason G Kettle, Sharan K Bagal, Derek Barratt, Michael S Bodnarchuk, Scott Boyd, Rachel Howells

J Med Chem· July 2023

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What is new in migraine management in children and young people?
Ne Ron Loh, William P Whitehouse, Rachel Howells

Arch Dis Child· December 2022

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Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS.
Jason G Kettle, Sharan K Bagal, Sue Bickerton, Michael S Bodnarchuk, Scott Boyd, Rachel Howells

J Med Chem· May 2022

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Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRAS.
Jason G Kettle, Sharan K Bagal, Sue Bickerton, Michael S Bodnarchuk, Jason Breed, Rachel Howells

J Med Chem· May 2020

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Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC).
Richard A Ward, Mark J Anderton, Paul Bethel, Jason Breed, Calum Cook, Rachel Howells

J Med Chem· December 2019

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Chronic post-traumatic headache in pediatrics.
Ishaq Abu-Arafeh, Rachel Howells

Pain Manag· July 2014

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Primary headaches in children under the age of 7 years.
Ishaq Abu-Arafeh, Rachel Howells

Curr Pain Headache Rep· March 2014

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Fifteen minute consultation: headache in children under 5 years of age.
Nadine McCrea, Rachel Howells

Arch Dis Child Educ Pract Ed· October 2013

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Going legal.
Tony Lopez, Rachel Howells, Simon Lindsay

Arch Dis Child Educ Pract Ed· February 2013

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Initial evaluation of EPSCALE, a rating scale that assesses the process of explanation and planning in the medical interview.
Jonathan Silverman, Julian Archer, Susan Gillard, Rachel Howells, John Benson

Patient Educ Couns· January 2011

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Newborn resuscitation training--which manikin.
Rachel Howells, John Madar

Resuscitation· August 2002

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