Publications by authors named "Jason Lester"

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Constitutive inflammation and epithelial-mesenchymal transition dictate sensitivity to nivolumab in CONFIRM: a placebo-controlled, randomised phase III trial.
Dean A Fennell, Kayleigh Hill, Min Zhang, Charlotte Poile, Sean Ewings, Jason F Lester

Nat Commun· July 2025

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Environmental impact of colorectal cancer screening with colonoscopy and multi-target stool DNA (mt-sDNA) testing.
Rebecca Alcock, Aasma Shaukat, John B Kisiel, Lyndon V Hernandez, Benjo A Delarmente, Jason Lester

Health Aff Sch· March 2025

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Stereotactic Magnetic Resonance-Guided Daily Adaptive Radiation Therapy for Localized Prostate Cancer: Acute and Late Patient-Reported Toxicity Outcomes.
Killian Nugent, Prantik Das, Dan Ford, Ami Sabharwal, Carla Perna, Jason Lester

Adv Radiat Oncol· September 2024

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Author Correction: The evolution of lung cancer and impact of subclonal selection in TRACERx.
Alexander M Frankell, Michelle Dietzen, Maise Al Bakir, Emilia L Lim, Takahiro Karasaki, Jason F Lester

Nature· July 2024

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The evolution of lung cancer and impact of subclonal selection in TRACERx.
Alexander M Frankell, Michelle Dietzen, Maise Al Bakir, Emilia L Lim, Takahiro Karasaki, Jason F Lester

Nature· April 2023

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Olaparib maintenance versus placebo monotherapy in patients with advanced non-small cell lung cancer (PIN): A multicentre, randomised, controlled, phase 2 trial.
Dean A Fennell, Catharine Porter, Jason Lester, Sarah Danson, Fiona Blackhall

EClinicalMedicine· October 2022

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Prognostic factors for survival and ambulatory status at 8 weeks with metastatic spinal cord compression in the SCORAD randomised trial.
Peter J Hoskin, Kirsten Hopkins, Vivek Misra, Tanya Holt, Rhona McMenemin, Jason F Lester

Radiother Oncol· August 2022

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Cost-utility analysis of adding abiraterone acetate plus prednisone/prednisolone to long-term hormone therapy in newly diagnosed advanced prostate cancer in England: Lifetime decision model based on STAMPEDE trial data.
Caroline S Clarke, Rachael M Hunter, Andrea Gabrio, Christopher D Brawley, Fiona C Ingleby, Jason F Lester

PLoS One· June 2022

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Active symptom control with or without oral vinorelbine in patients with relapsed malignant pleural mesothelioma (VIM): A randomised, phase 2 trial.
Dean A Fennell, Catharine Porter, Jason Lester, Sarah Danson, Paul Taylor

EClinicalMedicine· June 2022

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Addition of nintedanib or placebo to neoadjuvant gemcitabine and cisplatin in locally advanced muscle-invasive bladder cancer (NEOBLADE): a double-blind, randomised, phase 2 trial.
Syed A Hussain, Jason F Lester, Richard Jackson, Matthew Gornall, Muneeb Qureshi

Lancet Oncol· May 2022

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Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial.
Dean A Fennell, Sean Ewings, Christian Ottensmeier, Raffaele Califano, Gerard G Hanna, Jason F Lester

Lancet Oncol· November 2021

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Retrospective analysis of real-world treatment patterns and clinical outcomes in patients with advanced non-small cell lung cancer starting first-line systemic therapy in the United Kingdom.
Jason Lester, Carles Escriu, Sarah Khan, Emma Hudson, Talal Mansy

BMC Cancer· May 2021

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Timing of radiotherapy after radical prostatectomy (RADICALS-RT): a randomised, controlled phase 3 trial.
Christopher C Parker, Noel W Clarke, Adrian D Cook, Howard G Kynaston, Peter Meidahl Petersen, Jason Lester

Lancet· October 2020

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A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin.
Robert Jones, Simon Crabb, John Chester, Tony Elliott, Robert Huddart, Jason Lester

BJU Int· August 2020

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Chemotherapy decision-making in advanced lung cancer: a prospective qualitative study.
Annmarie Nelson, Mirella Longo, Anthony Byrne, Stephanie Sivell, Simon Noble, Jason Lester

BMJ Support Palliat Care· August 2020

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Tyrosine Kinase Inhibitors for the Treatment of EGFR Mutation-Positive Non-Small-Cell Lung Cancer: A Clash of the Generations.
Riyaz Shah, Jason F Lester

Clin Lung Cancer· May 2020

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Effect of Single-Fraction vs Multifraction Radiotherapy on Ambulatory Status Among Patients With Spinal Canal Compression From Metastatic Cancer: The SCORAD Randomized Clinical Trial.
Peter J Hoskin, Kirsten Hopkins, Vivek Misra, Tanya Holt, Rhona McMenemin, Jason F Lester

JAMA· December 2019

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Assessment of contour variability in target volumes and organs at risk in lung cancer radiotherapy.
Yatman Tsang, Peter Hoskin, Emiliano Spezi, David Landau, Jason Lester

Tech Innov Patient Support Radiat Oncol· June 2019

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Performance status agreement assessed by the patient and clinician in a rapid access lung cancer service: Can either predict completion of treatment?
Jemima T Collins, Simon Noble, Helen E Davies, Daniel Farewell, Jason F Lester

Eur J Cancer Care (Engl)· May 2019

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Accelerated, Dose escalated, Sequential Chemoradiotherapy in Non-small-cell lung cancer (ADSCaN): a protocol for a randomised phase II study.
Matthew Q F Hatton, Claire Anne Lawless, Corinne Faivre-Finn, David Landau, Jason F Lester

BMJ Open· January 2019

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Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial.
Christopher C Parker, Nicholas D James, Christopher D Brawley, Noel W Clarke, Alex P Hoyle, Jason F Lester

Lancet· December 2018

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A single centre phase II trial to assess the immunological activity of TroVax® plus pemetrexed/cisplatin in patients with malignant pleural mesothelioma - the SKOPOS trial.
Jason F Lester, Angela C Casbard, Saly Al-Taei, Richard Harrop, Lajos Katona

Oncoimmunology· September 2018

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CONFIRM: a double-blind, placebo-controlled phase III clinical trial investigating the effect of nivolumab in patients with relapsed mesothelioma: study protocol for a randomised controlled trial.
Dean A Fennell, Emma Kirkpatrick, Kelly Cozens, Mavis Nye, Jason Lester

Trials· April 2018

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Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Christopher Abbosh, Nicolai J Birkbak, Gareth A Wilson, Mariam Jamal-Hanjani, Tudor Constantin, Jason F Lester

Nature· February 2018

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The burden of neutropenic sepsis in patients with advanced non-small cell lung cancer treated with single-agent docetaxel: A retrospective study.
Toby Talbot, Adam Dangoor, Riyaz Shah, Jay Naik, Denis Talbot, Jason F Lester

Lung Cancer· November 2017

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