Publications by authors named "Jason P Riley"

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The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis.
Jeffery M Cowden, Fuqu Yu, Homayon Banie, Mandana Farahani, Ping Ling, Jason P Riley

Ann Rheum Dis· March 2014

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Mast cell mediators cause early allergic bronchoconstriction in guinea-pigs in vivo: a model of relevance to asthma.
Jason P Riley, Barbara Fuchs, Lisa Sjöberg, Gunnar P Nilsson, Lars Karlsson

Clin Sci (Lond)· December 2013

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Antagonism of the histamine H4 receptor reduces LPS-induced TNF production in vivo.
Jeffery M Cowden, Fuqu Yu, Mamatha Challapalli, Jing-Feng Huang, Sunhwa Kim, Jason P Riley

Inflamm Res· June 2013

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Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.
Wendy Eccles, Jonathan M Blevitt, Jamila N Booker, Christa C Chrovian, Shelby Crawford, Jason P Riley

Bioorg Med Chem Lett· February 2013

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Azabenzthiazole inhibitors of leukotriene A₄ hydrolase.
Virginia M Tanis, Genesis M Bacani, Jonathan M Blevitt, Christa C Chrovian, Shelby Crawford, Jason P Riley

Bioorg Med Chem Lett· December 2012

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Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines.
Jeffery M Cowden, Jason P Riley, Jing Ying Ma, Robin L Thurmond, Paul J Dunford

Respir Res· June 2010

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Leukotriene A(4) hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness.
Navin L Rao, Jason P Riley, Homayon Banie, Xiaohua Xue, Binggang Sun

Am J Respir Crit Care Med· May 2010

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Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Cheryl A Grice, Kevin L Tays, Brad M Savall, Jianmei Wei, Christopher R Butler, Jason P Riley

J Med Chem· July 2008

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A novel B-RAF inhibitor blocks interleukin-8 (IL-8) synthesis in human melanoma xenografts, revealing IL-8 as a potential pharmacodynamic biomarker.
Shelby Crawford, Daniel Belajic, Jianmei Wei, Jason P Riley, Paul J Dunford

Mol Cancer Ther· March 2008

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Anti-inflammatory activity of a potent, selective leukotriene A4 hydrolase inhibitor in comparison with the 5-lipoxygenase inhibitor zileuton.
Navin L Rao, Paul J Dunford, Xiaohua Xue, Xiaohui Jiang, Katherine A Lundeen, Jason P Riley

J Pharmacol Exp Ther· June 2007

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The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells.
Paul J Dunford, Niall O'Donnell, Jason P Riley, Kacy N Williams, Lars Karlsson

J Immunol· June 2006

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Maternal and fetal distribution of a phosphorothioate oligonucleotide in rats after intravenous infusion.
Nicole V Soucy, Jason P Riley, Michael V Templin, Richard Geary, Ann de Peyster

Birth Defects Res B Dev Reprod Toxicol· February 2006

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A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties.
Robin L Thurmond, Pragnya J Desai, Paul J Dunford, Wai-Ping Fung-Leung, Claudia L Hofstra, Jason P Riley

J Pharmacol Exp Ther· April 2004

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Identification of a potent and selective noncovalent cathepsin S inhibitor.
Robin L Thurmond, Siquan Sun, Clark A Sehon, Sherry M Baker, Hui Cai, Jason P Riley

J Pharmacol Exp Ther· January 2004

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