Publications by authors named "Jason Pyrdol"

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A CAR enhancer increases the activity and persistence of CAR T cells.
Taha Rakhshandehroo, Shreya R Mantri, Heydar Moravej, Benjamin B V Louis, Ali Salehi Farid, Jason Pyrdol

Nat Biotechnol· June 2025

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Dissecting the immune landscape in pediatric high-grade glioma reveals cell state changes under therapeutic pressure.
Jenna J LaBelle, Rebecca D Haase, Alexander Beck, Jacob Haase, Li Jiang, Jason Pyrdol

Cell Rep Med· May 2025

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Targeting of the CD161 inhibitory receptor enhances T-cell-mediated immunity against hematological malignancies.
Francesca Alvarez Calderon, Byong H Kang, Oleksandr Kyrysyuk, Shiwei Zheng, Hao Wang, Jason Pyrdol

Blood· March 2024

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Heterogeneity and transcriptional drivers of triple-negative breast cancer.
Bojana Jovanović, Daniel Temko, Laura E Stevens, Marco Seehawer, Anne Fassl, Jason Pyrdol

Cell Rep· December 2023

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Addressing Tumor Heterogeneity by Sensitizing Resistant Cancer Cells to T cell-Secreted Cytokines.
Yoshinaga Ito, Deng Pan, Wubing Zhang, Xixi Zhang, Tiffany Y Juan, Jason W Pyrdol

Cancer Discov· May 2023

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Cytokine conjugation to enhance T cell therapy.
Yutong Liu, Kwasi Adu-Berchie, Joshua M Brockman, Matthew Pezone, David K Y Zhang, Jason W Pyrdol

Proc Natl Acad Sci U S A· January 2023

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Breast cancer prevention by short-term inhibition of TGFβ signaling.
Maša Alečković, Simona Cristea, Carlos R Gil Del Alcazar, Pengze Yan, Lina Ding, Jason Pyrdol

Nat Commun· December 2022

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A vaccine targeting resistant tumours by dual T cell plus NK cell attack.
Soumya Badrinath, Maxence O Dellacherie, Aileen Li, Shiwei Zheng, Xixi Zhang, Jason W Pyrdol

Nature· June 2022

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CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells.
Sushil Kumar, Zexian Zeng, Archis Bagati, Rong En Tay, Lionel A Sanz, Jason W Pyrdol

Cancer Discov· August 2021

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Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma.
Zhuting Hu, Donna E Leet, Rosa L Allesøe, Giacomo Oliveira, Shuqiang Li, Jason Pyrdol

Nat Med· March 2021

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Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.
Nathan D Mathewson, Orr Ashenberg, Itay Tirosh, Simon Gritsch, Elizabeth M Perez, Jason Pyrdol

Cell· March 2021

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Integrin αvβ6-TGFβ-SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer.
Archis Bagati, Sushil Kumar, Peng Jiang, Jason Pyrdol, Angela E Zou

Cancer Cell· January 2021

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Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma.
Johannes Gojo, Bernhard Englinger, Li Jiang, Jens M Hübner, McKenzie L Shaw, Jason Pyrdol

Cancer Cell· July 2020

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Inhibition of MICA and MICB Shedding Elicits NK-Cell-Mediated Immunity against Tumors Resistant to Cytotoxic T Cells.
Lucas Ferrari de Andrade, Sushil Kumar, Adrienne M Luoma, Yoshinaga Ito, Pedro Henrique Alves da Silva, Jason W Pyrdol

Cancer Immunol Res· June 2020

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Discovery of specialized NK cell populations infiltrating human melanoma metastases.
Lucas Ferrari de Andrade, Yuheng Lu, Adrienne Luoma, Yoshinaga Ito, Deng Pan, Jason W Pyrdol

JCI Insight· December 2019

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Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity.
Yoshinaga Ito, Orr Ashenberg, Jason Pyrdol, Adrienne M Luoma, Orit Rozenblatt-Rosen

J Exp Med· October 2018

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Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity.
Lucas Ferrari de Andrade, Rong En Tay, Deng Pan, Adrienne M Luoma, Yoshinaga Ito, Jason W Pyrdol

Science· March 2018

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Erratum: The microRNA miR-31 inhibits CD8 T cell function in chronic viral infection.
Howell F Moffett, Adam N R Cartwright, Hye-Jung Kim, Jernej Godec, Jason Pyrdol

Nat Immunol· September 2017

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The microRNA miR-31 inhibits CD8 T cell function in chronic viral infection.
Howell F Moffett, Adam N R Cartwright, Hye-Jung Kim, Jernej Godec, Jason Pyrdol

Nat Immunol· July 2017

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Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling.
Jessica Dobbins, Etienne Gagnon, Jernej Godec, Jason Pyrdol, Dario A A Vignali

Sci Signal· July 2016

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Crystal structure of the HLA-DM-HLA-DR1 complex defines mechanisms for rapid peptide selection.
Wouter Pos, Dhruv K Sethi, Melissa J Call, Monika-Sarah E D Schulze, Anne-Kathrin Anders, Jason Pyrdol

Cell· December 2012

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A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC.
Dhruv K Sethi, David A Schubert, Anne-Kathrin Anders, Annie Heroux, Daniel A Bonsor, Jason Pyrdol

J Exp Med· January 2011

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Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor.
Michael Hahn, Melissa J Nicholson, Jason Pyrdol, Kai W Wucherpfennig

Nat Immunol· May 2005

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Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis.
Jayagopala Reddy, Zsolt Illes, Xingmin Zhang, Jeffrey Encinas, Jason Pyrdol

Proc Natl Acad Sci U S A· October 2004

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Stoichiometry of the T-cell receptor-CD3 complex and key intermediates assembled in the endoplasmic reticulum.
Matthew E Call, Jason Pyrdol, Kai W Wucherpfennig

EMBO J· June 2004

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