Publications by authors named "Simona Cristea"

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Towards multimodal foundation models in molecular cell biology.
Haotian Cui, Alejandro Tejada-Lapuerta, Maria Brbić, Julio Saez-Rodriguez, Simona Cristea

Nature· April 2025

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Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer.
Julien Dilly, Megan T Hoffman, Laleh Abbassi, Ziyue Li, Francesca Paradiso, Simona Cristea

Cancer Discov· November 2024

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Author Correction: Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments.
Michalina Janiszewska, Doris P Tabassum, Zafira Castaño, Simona Cristea, Kimiyo N Yamamoto

Nat Cell Biol· May 2024

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Predicting patient outcomes after treatment with immune checkpoint blockade: A review of biomarkers derived from diverse data modalities.
Yang Liu, Jennifer Altreuter, Sudheshna Bodapati, Simona Cristea, Cheryl J Wong

Cell Genom· January 2024

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Peripheral blood TCR clonotype diversity as an age-associated marker of breast cancer progression.
Jun Nishida, Simona Cristea, Sudheshna Bodapati, Julieann Puleo, Gali Bai

Proc Natl Acad Sci U S A· December 2023

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A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression.
Zhihong Chen, Bruno Giotti, Milota Kaluzova, Montse Puigdelloses Vallcorba, Kavita Rawat, Simona Cristea

J Clin Invest· November 2023

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H3K36 methylation maintains cell identity by regulating opposing lineage programmes.
Michael S Hoetker, Masaki Yagi, Bruno Di Stefano, Justin Langerman, Simona Cristea

Nat Cell Biol· August 2023

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Single-cell heterogeneity of EGFR and CDK4 co-amplification is linked to immune infiltration in glioblastoma.
Kacper A Walentynowicz, Dalit Engelhardt, Simona Cristea, Shreya Yadav, Ugoma Onubogu

Cell Rep· March 2023

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Breast cancer prevention by short-term inhibition of TGFβ signaling.
Maša Alečković, Simona Cristea, Carlos R Gil Del Alcazar, Pengze Yan, Lina Ding

Nat Commun· December 2022

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Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk.
Rick A C M Boonen, Wouter W Wiegant, Nandi Celosse, Bas Vroling, Stephan Heijl, Simona Cristea

Cancer Res· February 2022

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Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells.
Masaki Yagi, Fei Ji, Jocelyn Charlton, Simona Cristea, Kathleen Messemer

Genes Dev· September 2021

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Systematic tissue collection during clinical breast biopsy is feasible, safe and enables high-content translational analyses.
Siang-Boon Koh, Brian N Dontchos, Veerle Bossuyt, Christine Edmonds, Simona Cristea

NPJ Precis Oncol· September 2021

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The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer.
Michalina Janiszewska, Shayna Stein, Otto Metzger Filho, Jennifer Eng, Natalie L Kingston, Simona Cristea

JCI Insight· June 2021

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Clonal evolution driven by superdriver mutations.
Patrick Grossmann, Simona Cristea, Niko Beerenwinkel

BMC Evol Biol· July 2020

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Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ.
Lina Ding, Ying Su, Anne Fassl, Kunihiko Hinohara, Xintao Qiu, Simona Cristea

Nat Commun· September 2019

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Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments.
Michalina Janiszewska, Doris P Tabassum, Zafira Castaño, Simona Cristea, Kimiyo N Yamamoto

Nat Cell Biol· July 2019

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Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity.
Aron Gyuris, Jose Navarrete-Perea, Ala Jo, Simona Cristea, Shuang Zhou

Cell Rep· June 2019

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Simultaneous Integration of Multi-omics Data Improves the Identification of Cancer Driver Modules.
Dana Silverbush, Simona Cristea, Gali Yanovich-Arad, Tamar Geiger, Niko Beerenwinkel

Cell Syst· May 2019

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Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq.
Mihriban Karaayvaz, Simona Cristea, Shawn M Gillespie, Anoop P Patel, Ravindra Mylvaganam

Nat Commun· September 2018

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Principles of Systems Biology, No. 31.
Hyunghoon Cho, Bonnie Berger, Jian Peng, Cyril Galitzine, Olga Vitek, Ileana M Cristea, Simona Cristea

Cell Syst· August 2018

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Dissecting the mammary gland one cell at a time.
Simona Cristea, Kornelia Polyak

Nat Commun· June 2018

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Recurring Amplification at 11q22.1-q22.2 Locus Plays an Important Role in Lymph Node Metastasis and Radioresistance in OSCC.
Priyanka G Bhosale, Manishkumar Pandey, Simona Cristea, Mickey Shah, Asawari Patil

Sci Rep· November 2017

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pathTiMEx: Joint Inference of Mutually Exclusive Cancer Pathways and Their Progression Dynamics.
Simona Cristea, Jack Kuipers, Niko Beerenwinkel

J Comput Biol· June 2017

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Chromosomal Alterations and Gene Expression Changes Associated with the Progression of Leukoplakia to Advanced Gingivobuccal Cancer.
Priyanka G Bhosale, Simona Cristea, Srikant Ambatipudi, Rajiv S Desai, Rajiv Kumar

Transl Oncol· June 2017

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Sulforaphane Preconditioning Sensitizes Human Colon Cancer Cells towards the Bioreductive Anticancer Prodrug PR-104A.
Melanie M Erzinger, Cédric Bovet, Katrin M Hecht, Sabine Senger, Pascale Winiker, Simona Cristea

PLoS One· August 2016

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