Publications by authors named "Justin Langerman"

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Linking single-cell transcriptomes with secretion using SEC-seq.
Justin Langerman, Sevana Baghdasarian, Rene Yu-Hong Cheng, Richard G James, Kathrin Plath

Nat Protoc· July 2025

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Genetic Screen in a Preclinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities.
Jack Freeland, Maria Muñoz, Edmond O'Donnell, Justin Langerman, Morgan Darrow

Clin Cancer Res· November 2024

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Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity.
Prabhat K Purbey, Joowon Seo, Manash K Paul, Keisuke S Iwamoto, Allison E Daly, Justin Langerman

Cell Rep· June 2024

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Loss of cell junctional components and matrix alterations drive cell desquamation and fibrotic changes in Idiopathic Pulmonary Fibrosis.
Rachana R Chandran, Preethi Vijayaraj, Rolando Garcia-Milian, Jade King, Kristen Castillo, Justin Langerman

bioRxiv· June 2024

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Associating growth factor secretions and transcriptomes of single cells in nanovials using SEC-seq.
Shreya Udani, Justin Langerman, Doyeon Koo, Sevana Baghdasarian, Brian Cheng

Nat Nanotechnol· March 2024

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H3K36 methylation maintains cell identity by regulating opposing lineage programmes.
Michael S Hoetker, Masaki Yagi, Bruno Di Stefano, Justin Langerman, Simona Cristea

Nat Cell Biol· August 2023

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Secretion encoded single-cell sequencing (SEC-seq) uncovers gene expression signatures associated with high VEGF-A secretion in mesenchymal stromal cells.
Shreya Udani, Justin Langerman, Doyeon Koo, Sevana Baghdasarian, Brian Cheng

bioRxiv· January 2023

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Oct4:Sox2 binding is essential for establishing but not maintaining active and silent states of dynamically regulated genes in pluripotent cells.
Jerry Hung-Hao Lo, Miguel Edwards, Justin Langerman, Rupa Sridharan, Kathrin Plath

Genes Dev· October 2022

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Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis.
Thomas Allison, Justin Langerman, Shan Sabri, Marcos Otero-Garcia, Andrew Lund

Stem Cell Reports· October 2021

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Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition.
Gianni Carraro, Justin Langerman, Shan Sabri, Zareeb Lorenzana, Arunima Purkayastha

Nat Med· May 2021

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Species-Specific Relationships between DNA and Chromatin Properties of CpG Islands in Embryonic Stem Cells and Differentiated Cells.
Justin Langerman, David Lopez, Matteo Pellegrini, Stephen T Smale

Stem Cell Reports· April 2021

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SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition.
Peter J Mullen, Gustavo Garcia, Arunima Purkayastha, Nedas Matulionis, Ernst W Schmid, Justin Langerman

Nat Commun· March 2021

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Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response.
Arunima Purkayastha, Chandani Sen, Gustavo Garcia, Justin Langerman, David W Shia

Cell Stem Cell· December 2020

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A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells.
Haibin Xi, Justin Langerman, Shan Sabri, Peggie Chien, Courtney S Young

Cell Stem Cell· July 2020

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A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells.
Haibin Xi, Justin Langerman, Shan Sabri, Peggie Chien, Courtney S Young

Cell Stem Cell· July 2020

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Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stem cell-derived airway repair response.
Arunima Purkayastha, Chandani Sen, Gustavo Garcia, Justin Langerman, Preethi Vijayaraj

bioRxiv· July 2020

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A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation.
Damon Polioudakis, Luis de la Torre-Ubieta, Justin Langerman, Andrew G Elkins, Xu Shi

Neuron· September 2019

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Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells.
Thomas F Allison, Andrew J H Smith, Konstantinos Anastassiadis, Jackie Sloane-Stanley, Veronica Biga, Justin Langerman

Stem Cell Reports· June 2018

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X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.
Vincent Pasque, Rahul Karnik, Constantinos Chronis, Paula Petrella, Justin Langerman

Stem Cell Reports· May 2018

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Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence.
Minori Ohashi, Elena Korsakova, Denise Allen, Peiyee Lee, Kai Fu, Justin Langerman

Stem Cell Reports· May 2018

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Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation.
Sanjeet Patel, Giancarlo Bonora, Anna Sahakyan, Rachel Kim, Constantinos Chronis, Justin Langerman

Cell Rep· January 2017

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Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation.
Anna Sahakyan, Rachel Kim, Constantinos Chronis, Shan Sabri, Giancarlo Bonora, Justin Langerman

Cell Stem Cell· January 2017

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