Publications by authors named "Jason R Dobson"

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Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours.
Jordi Rodon, Guillem Argilés, Roisin M Connolly, Ulka Vaishampayan, Maja de Jonge, Jason R Dobson

Br J Cancer· July 2021

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Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-Based Subtypes.
Li Zhang, Kenzie D MacIsaac, Ting Zhou, Pei-Yu Huang, Chunlin Xin, Jason R Dobson

Mol Cancer Res· December 2017

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Identifying Nuclear Matrix-Attached DNA Across the Genome.
Jason R Dobson, Deli Hong, A Rasim Barutcu, Hai Wu, Anthony N Imbalzano

J Cell Physiol· June 2017

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A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid Tumors.
Birgit Geoerger, Franck Bourdeaut, Steven G DuBois, Matthias Fischer, James I Geller, Jason R Dobson

Clin Cancer Res· May 2017

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Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition.
Deli Hong, Terri L Messier, Coralee E Tye, Jason R Dobson, Andrew J Fritz

Oncotarget· March 2017

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A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and Lymphomas.
Jeffrey R Infante, Philippe A Cassier, John F Gerecitano, Petronella O Witteveen, Rashmi Chugh, Jason R Dobson

Clin Cancer Res· December 2016

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Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.
Ying-Nan P Chen, Matthew J LaMarche, Ho Man Chan, Peter Fekkes, Jorge Garcia-Fortanet, Jason R Dobson

Nature· July 2016

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Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation.
Guray Kuzu, Emily G Kaye, Jessica Chery, Trevor Siggers, Lin Yang, Jason R Dobson

PLoS Genet· July 2016

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The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation.
Qiong Wu, Pasil Madany, Jason R Dobson, Jake M Schnabl, Soni Sharma

Oncotarget· June 2016

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The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.
Qiong Wu, Pasil Madany, Jacqueline Akech, Jason R Dobson, Stephen Douthwright

J Cell Physiol· November 2015

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Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1.
Xuhui Zhang, Hai Wu, Jason R Dobson, Gillian Browne, Deli Hong

J Cell Biochem· September 2015

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Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes.
Mark D M Leiserson, Fabio Vandin, Hsin-Ta Wu, Jason R Dobson, Jonathan V Eldridge

Nat Genet· February 2015

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The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter.
A Rasim Barutcu, Phillip W L Tai, Hai Wu, Jonathan A R Gordon, Troy W Whitfield, Jason R Dobson

Nucleic Acids Res· January 2015

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hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3.
Jason R Dobson, Hanna Taipaleenmäki, Yu-Jie Hu, Deli Hong, Andre J van Wijnen

Cancer Cell Int· August 2014

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Identifying driver mutations in sequenced cancer genomes: computational approaches to enable precision medicine.
Benjamin J Raphael, Jason R Dobson, Layla Oesper, Fabio Vandin

Genome Med· June 2014

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Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis.
Hai Wu, Troy W Whitfield, Jonathan A R Gordon, Jason R Dobson, Phillip W L Tai

Genome Biol· March 2014

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Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility.
David T Leong, Joleen Lim, Xuewei Goh, Jitesh Pratap, Barry P Pereira, Jason R Dobson

Breast Cancer Res· February 2013

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A RUNX2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation.
Syed A Ali, Jason R Dobson, Jane B Lian, Janet L Stein, Andre J van Wijnen

J Cell Sci· June 2012

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Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes.
Syed A Ali, Sayyed K Zaidi, Jason R Dobson, Abdul R Shakoori, Jane B Lian

Proc Natl Acad Sci U S A· March 2010

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