Publications by authors named "Jason Tonne"

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T cell exhaustion in poorly immunogenic HCC is partially rescued by checkpoint blockade but suppressed by oncolytic virotherapy.
Thanich Sangsuwannukul, Benjamin Kendall, Jason Tonne, Olivia Liseth, Jill Thompson

Mol Ther· December 2025

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Exploiting viral infection/vaccination to focus high-affinity T cell populations into tumors using oncolytic viro-immunotherapy.
Alexa Veliz Rios, Muriel Metko, Jason Tonne, Jill Thompson, Benjamin Kendall

Mol Ther· November 2025

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Immunodominant antiviral T cell responses outcompete immuno-subdominant antitumor responses to reduce the efficacy of oncolytic viroimmunotherapy.
Richard Vile, Benjamin Kendall, Olivia Liseth, Thanich Sangsuwannukul, Natalie Elliott, Jason Tonne

Res Sq· March 2025

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APOBEC3B expression in 293T viral producer cells drives mutations in chimeric antigen receptors and reduces CAR T cell efficacy.
Jack Swanson, Jason Tonne, Thanich Sangsuwannukul, Jill Thompson, Benjamin Kendall

Mol Ther Oncol· December 2024

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Cancer Immunotherapy Using AIRE Conditioning of the Tumor Epitopeome.
Richard Vile, Jose Pulido, Alex Chen, Benjamin Kendall, Jason Tonne

Res Sq· November 2024

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Intranasal Prime-Boost with Spike Vectors Generates Antibody and T-Cell Responses at the Site of SARS-CoV-2 Infection.
Muriel Metko, Jason Tonne, Alexa Veliz Rios, Jill Thompson, Haley Mudrick

Vaccines (Basel)· October 2024

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Smoldering oncolysis by foamy virus carrying CD19 as a CAR target escapes CAR T detection by genomic modification.
Jason M Tonne, Karol Budzik, Talia Fernandez Carrasco, Landon Ebbert, Jill Thompson

Mol Ther Oncol· September 2024

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Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response.
Mason J Webb, Thanich Sangsuwannukul, Jacob van Vloten, Laura Evgin, Benjamin Kendall, Jason Tonne

Nat Commun· June 2024

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A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses.
Katherine E R Smith, Kah-Whye Peng, Jose S Pulido, Adam J Weisbrod, Carrie A Strand, Jason M Tonne

Front Immunol· December 2023

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Chimerization of the Anti-Viral CD8 T Cell Response with A Broad Anti-Tumor T Cell Response Reverses Inhibition of Checkpoint Blockade Therapy by Oncolytic Virotherapy.
Richard Vile, Mason Webb, Jacob van Vloten, Laura Evgin, Thanich Sangsuwannukul, Jason Tonne

Res Sq· November 2023

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Trap and ambush therapy using sequential primary and tumor escape-selective oncolytic viruses.
Mason J Webb, Timothy Kottke, Benjamin L Kendall, Jack Swanson, Chisom Uzendu, Jason Tonne

Mol Ther Oncolytics· June 2023

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Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice.
Laura Evgin, Tim Kottke, Jason Tonne, Jill Thompson, Amanda L Huff

Sci Transl Med· April 2022

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Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy.
Timothy Kottke, Jason Tonne, Laura Evgin, Christopher B Driscoll, Jacob van Vloten

Nat Commun· March 2021

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Ad-CD40L mobilizes CD4 T cells for the treatment of brainstem tumors.
Phonphimon Wongthida, Matthew R Schuelke, Christopher B Driscoll, Timothy Kottke, Jill M Thompson, Jason Tonne

Neuro Oncol· December 2020

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Vesicular Stomatitis Virus Encoding a Destabilized Tumor Antigen Improves Activation of Anti-tumor T Cell Responses.
Amanda L Huff, Laura Evgin, Jill Thompson, Tim Kottke, Christopher B Driscoll, Jason Tonne

Mol Ther· December 2020

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Oncolytic virus-derived type I interferon restricts CAR T cell therapy.
Laura Evgin, Amanda L Huff, Phonphimon Wongthida, Jill Thompson, Tim Kottke, Jason Tonne

Nat Commun· June 2020

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Generation of a Tumor-Specific Chemokine Gradient Using Oncolytic Vesicular Stomatitis Virus Encoding CXCL9.
Elizabeth C Eckert, Rebecca A Nace, Jason M Tonne, Laura Evgin, Richard G Vile

Mol Ther Oncolytics· March 2020

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APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy.
Christopher B Driscoll, Matthew R Schuelke, Timothy Kottke, Jill M Thompson, Phonphimon Wongthida, Jason M Tonne

Nat Commun· February 2020

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Targeted Derivation of Organotypic Glucose- and GLP-1-Responsive β Cells Prior to Transplantation into Diabetic Recipients.
Yaxi Zhu, Jason M Tonne, Qian Liu, Claire A Schreiber, Zhiguang Zhou

Stem Cell Reports· August 2019

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Hyperinsulinemic hypoglycemia subtype glucokinase V91L mutant induces necrosis in β-cells via ATP depletion.
Brian Lu, Jason M Tonne, Miguel Munoz-Gomez, Yasuhiro Ikeda

Biochem Biophys Rep· March 2019

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Impaired β-cell glucokinase as an underlying mechanism in diet-induced diabetes.
Brian Lu, Kiran Kurmi, Miguel Munoz-Gomez, Egon J Jacobus Ambuludi, Jason M Tonne

Dis Model Mech· June 2018

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Divergent susceptibilities to AAV-SaCas9-gRNA vector-mediated genome-editing in a single-cell-derived cell population.
Salma G Morsy, Jason M Tonne, Yaxi Zhu, Brian Lu, Karol Budzik

BMC Res Notes· December 2017

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Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.
Marissa J Schafer, Thomas A White, Glenda Evans, Jason M Tonne, Grace C Verzosa

Diabetes· June 2016

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Tumor-Free Transplantation of Patient-Derived Induced Pluripotent Stem Cell Progeny for Customized Islet Regeneration.
Moustafa M El Khatib, Seiga Ohmine, Egon J Jacobus, Jason M Tonne, Salma G Morsy

Stem Cells Transl Med· May 2016

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B-Type Natriuretic Peptide Deletion Leads to Progressive Hypertension, Associated Organ Damage, and Reduced Survival: Novel Model for Human Hypertension.
Sara J Holditch, Claire A Schreiber, Ryan Nini, Jason M Tonne, Kah-Whye Peng

Hypertension· July 2015

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