Publications by authors named "Tim Kottke"

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Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice.
Laura Evgin, Tim Kottke, Jason Tonne, Jill Thompson, Amanda L Huff

Sci Transl Med· April 2022

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Vesicular Stomatitis Virus Encoding a Destabilized Tumor Antigen Improves Activation of Anti-tumor T Cell Responses.
Amanda L Huff, Laura Evgin, Jill Thompson, Tim Kottke, Christopher B Driscoll

Mol Ther· December 2020

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Oncolytic virus-derived type I interferon restricts CAR T cell therapy.
Laura Evgin, Amanda L Huff, Phonphimon Wongthida, Jill Thompson, Tim Kottke

Nat Commun· June 2020

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Subversion of NK-cell and TNFα Immune Surveillance Drives Tumor Recurrence.
Tim Kottke, Laura Evgin, Kevin G Shim, Diana Rommelfanger, Nicolas Boisgerault

Cancer Immunol Res· November 2017

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Synthesis, Molecular Properties Estimations, and Dual Dopamine D and D Receptor Activities of Benzothiazole-Based Ligands.
Moritz Schübler, Bassem Sadek, Tim Kottke, Lilia Weizel, Holger Stark

Front Chem· September 2017

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Synthesis and biological activity of novel tert-amylphenoxyalkyl (homo)piperidine derivatives as histamine HR ligands.
Kamil J Kuder, Dorota Łażewska, Maria Kaleta, Gniewomir Latacz, Tim Kottke

Bioorg Med Chem· May 2017

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Inhibitory Receptors Induced by VSV Viroimmunotherapy Are Not Necessarily Targets for Improving Treatment Efficacy.
Kevin G Shim, Shane Zaidi, Jill Thompson, Tim Kottke, Laura Evgin

Mol Ther· April 2017

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Immunogenicity of self tumor associated proteins is enhanced through protein truncation.
Tim Kottke, Kevin G Shim, Vanesa Alonso-Camino, Shane Zaidi, Rosa Maria Diaz

Mol Ther Oncolytics· December 2016

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(2-Arylethenyl)-1,3,5-triazin-2-amines as a novel histamine H4 receptor ligands.
Katarzyna Kamińska, Julia Ziemba, Joanna Ner, Johannes Stephan Schwed, Dorota Łażewska, Tim Kottke

Eur J Med Chem· October 2015

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Development of Fluorine-18 Labeled Metabolically Activated Tracers for Imaging of Drug Efflux Transporters with Positron Emission Tomography.
Kerstin Sander, Eva Galante, Thibault Gendron, Elena Yiannaki, Niral Patel, Tim Kottke

J Med Chem· August 2015

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Mutated BRAF Emerges as a Major Effector of Recurrence in a Murine Melanoma Model After Treatment With Immunomodulatory Agents.
Shane Zaidi, Miran Blanchard, Kevin Shim, Elizabeth Ilett, Karishma Rajani, Tim Kottke

Mol Ther· May 2015

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Aryl-1,3,5-triazine derivatives as histamine H4 receptor ligands.
Dorota Łażewska, Małgorzata Więcek, Joanna Ner, Katarzyna Kamińska, Tim Kottke

Eur J Med Chem· August 2014

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The histamine H₄ receptor: targeting inflammatory disorders.
Miriam Walter, Tim Kottke, Holger Stark

Eur J Pharmacol· October 2011

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N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands.
Małgorzata Więcek, Tim Kottke, Xavier Ligneau, Walter Schunack, Roland Seifert

Bioorg Med Chem· May 2011

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Receptor-specific functional efficacies of alkyl imidazoles as dual histamine H3/H4 receptor ligands.
Tim Kottke, Kerstin Sander, Lilia Weizel, Erich H Schneider, Roland Seifert

Eur J Pharmacol· March 2011

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Kojic acid derivatives as histamine H(3) receptor ligands.
Kerstin Sander, Tim Kottke, Lilia Weizel, Holger Stark

Chem Pharm Bull (Tokyo)· October 2010

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In silico characterization of ligand binding modes in the human histamine H4 receptor and their impact on receptor activation.
Tim Werner, Kerstin Sander, Yusuf Tanrikulu, Tim Kottke, Ewgenij Proschak

Chembiochem· September 2010

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First metal-containing histamine H3 receptor ligands.
Kerstin Sander, Tim Kottke, Claas Hoffend, Miriam Walter, Lilia Weizel

Org Lett· June 2010

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Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.
Dorota Łazewska, Małgorzata Wiecek, Xavier Ligneau, Tim Kottke, Lilia Weizel

Bioorg Med Chem Lett· December 2009

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2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization.
Kerstin Sander, Tim Kottke, Yusuf Tanrikulu, Ewgenij Proschak, Lilia Weizel

Bioorg Med Chem· October 2009

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Immune-mediated antitumor activity of reovirus is required for therapy and is independent of direct viral oncolysis and replication.
Robin J Prestwich, Elizabeth J Ilett, Fiona Errington, Rosa M Diaz, Lynette P Steele, Tim Kottke

Clin Cancer Res· July 2009

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Homology model adjustment and ligand screening with a pseudoreceptor of the human histamine H4 receptor.
Yusuf Tanrikulu, Ewgenij Proschak, Tim Werner, Tim Geppert, Nickolay Todoroff, Tim Kottke

ChemMedChem· May 2009

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Histamine H3 receptor antagonists go to clinics.
Kerstin Sander, Tim Kottke, Holger Stark

Biol Pharm Bull· December 2008

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The inhibition of TNF-alpha anti-tumoral properties by blocking antibodies promotes tumor growth in a rat model.
Nicolas Larmonier, Dominique Cathelin, Claire Larmonier, Alexandra Nicolas, Delphine Merino, Tim Kottke

Exp Cell Res· July 2007

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Delivery of CCL21 to metastatic disease improves the efficacy of adoptive T-cell therapy.
Uma Thanarajasingam, Laura Sanz, Rosa Diaz, Jian Qiao, Luis Sanchez-Perez, Tim Kottke

Cancer Res· January 2007

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