Publications by authors named "Jason Yustein"

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Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas.
Harrison R Berger, Malina Maharana, Jeneffer Mirabal, Lyazat Kurenbekova, Alberto Delaidelli, Jason T Yustein

Cancer Immunol Res· October 2025

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Hypoxia Imaging as a Radiomics Signature in Tumors Using Novel F-Eu-Based Contrast Agents for Magnetic Resonance Imaging.
Susan A White, S A Amali S Subasinghe, Jonathan Romero, Abul Hassan Samee, Jason T Yustein

bioRxiv· October 2025

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Central memory-enriched Vγ9Vδ2 γδ T cells via TGF-β expansion demonstrate enhanced efficacy against metastatic osteosarcoma.
Jordan A Silva, Kokila Gunasinghe, Hunter C Jonus, Gianna M Branella, Austre Y Schiaffino Bustamante, Jason T Yustein

Front Immunol· September 2025

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The Role of in Tumor Immune Microenvironment Regulation: Insights and Future Directions.
Bikesh K Nirala, Jason T Yustein

Front Biosci (Landmark Ed)· September 2025

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Targeting Regnase-1 unleashes CAR T cell antitumor activity for osteosarcoma and creates a proinflammatory tumor microenvironment.
Adeleye O Adeshakin, Hao Shi, S Scott Perry, Heather Sheppard, Phuong Nguyen, Jason T Yustein

bioRxiv· May 2025

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A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function.
Daniel Landi, Shoba A Navai, Rebecca M Brock, Kristen Fousek, Zeid Nawas, Jason Yustein

Cancer Res Commun· March 2025

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The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma.
Shahid Banday, Alok K Mishra, Romana Rashid, Tianyi Ye, Amjad Ali, Jason T Yustein

Nat Commun· February 2025

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miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma.
Enrico Pozzo, Laura Yedigaryan, Nefele Giarratana, Chao-Chi Wang, Gabriel Miró Garrido, Jason T Yustein

Cell Rep· January 2025

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Intrinsic Epigenetic State of Primary Osteosarcoma Drives Metastasis.
Irtisha Singh, Nino Rainusso, Lyazat Kurenbekova, Bikesh K Nirala, Juan Dou, Jason T Yustein

Mol Cancer Res· September 2024

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Preclinical models for the study of pediatric solid tumors: focus on bone sarcomas.
D Isabel Petrescu, Jason T Yustein, Atreyi Dasgupta

Front Oncol· July 2024

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Systemic Cisplatin Does Not Affect the Bone Regeneration Process in a Critical Size Defect Murine Model.
Ava A Brozovich, Stefania Lenna, Carson Benner, Stefano Serpelloni, Francesca Paradiso, Jason T Yustein

ACS Biomater Sci Eng· March 2024

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Identification of an early survival prognostic gene signature for localized osteosarcoma patients.
Tajhal D Patel, Sandra L Grimm, Rupa S Kanchi, Tanmay Gandhi, Amrit Koirala, Jason T Yustein

Sci Rep· March 2024

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Intrinsic epigenetic state of primary osteosarcoma drives metastasis.
Irtisha Singh, Nino Rainusso, Lyazat Kurenbekova, Bikesh K Nirala, Juan Dou, Jason T Yustein

bioRxiv· November 2023

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Decoding the Impact of Tumor Microenvironment in Osteosarcoma Progression and Metastasis.
Bikesh K Nirala, Taku Yamamichi, D Isabel Petrescu, Tasnuva N Shafin, Jason T Yustein

Cancers (Basel)· October 2023

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MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma.
Bikesh K Nirala, Tajhal D Patel, Lyazat Kurenbekova, Ryan Shuck, Atreyi Dasgupta, Jason T Yustein

JCI Insight· July 2023

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Deciphering the Signaling Mechanisms of Osteosarcoma Tumorigenesis.
Bikesh K Nirala, Taku Yamamichi, Jason T Yustein

Int J Mol Sci· July 2023

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Toward quantification of hypoxia using fluorinated Eu-containing ratiometric probes.
S A Amali S Subasinghe, Caitlyn J Ortiz, Jonathan Romero, Cassandra L Ward, Alexander G Sertage, Jason T Yustein

Proc Natl Acad Sci U S A· April 2023

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Modeling Ewing Sarcoma Lung Metastasis.
Atreyi Dasgupta, Lyazat Kurenbekova, Tajhal D Patel, Kimal Rajapakshe, Gargi Ghosal, Jason Yustein

Curr Protoc· February 2023

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Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer.
Jose Thaiparambil, Jianrong Dong, Sandra L Grimm, Dimuthu Perera, Chandra Shekar R Ambati, Jason T Yustein

Cancer Med· January 2023

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LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination.
Susan V Tsang, Nino Rainusso, Meng Liu, Motonari Nomura, Tajhal D Patel, Jason T Yustein

Oncogene· December 2022

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Osteogenesis in the presence of chemotherapy: A biomimetic approach.
Ava A Brozovich, Stefania Lenna, Francesca Paradiso, Stefano Serpelloni, Patrick McCulloch, Jason T Yustein

J Tissue Eng· November 2022

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An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.
David S Shulman, Sarah B Whittle, Didier Surdez, Kelly M Bailey, Enrique de Álava, Jason T Yustein

NPJ Precis Oncol· September 2022

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A Mouse Holder for Awake Functional Imaging in Unanesthetized Mice: Applications in P Spectroscopy, Manganese-Enhanced Magnetic Resonance Imaging Studies, and Resting-State Functional Magnetic Resonance Imaging.
Lindsay C Fadel, Ivany V Patel, Jonathan Romero, I-Chih Tan, Shelli R Kesler, Jason T Yustein

Biosensors (Basel)· August 2022

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cBAF complex components and MYC cooperate early in CD8 T cell fate.
Ao Guo, Hongling Huang, Zhexin Zhu, Mark J Chen, Hao Shi, Jason T Yustein

Nature· July 2022

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Dual-Mode Tumor Imaging Using Probes That Are Responsive to Hypoxia-Induced Pathological Conditions.
S A Amali S Subasinghe, Robia G Pautler, Md Abul Hassan Samee, Jason T Yustein, Matthew J Allen

Biosensors (Basel)· June 2022

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