Publications by authors named "Javiera Cortes-Rios"

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A Step-by-Step Workflow for Performing In Silico Clinical Trials With Nonlinear Mixed Effects Models.
Javiera Cortés-Ríos, Mindy Magee, Anna Sher, William J Jusko, Rajat Desikan

CPT Pharmacometrics Syst Pharmacol· December 2025

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Insights Into Aldosterone Regulation Through Pharmacokinetic-Pharmacodynamic Modeling of an Aldosterone Synthase Inhibitor.
Javiera Cortés-Ríos, William J Jusko

Clin Pharmacol Ther· November 2025

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Dynamic modelling of cell cycle arrest through integrated single-cell and mathematical modelling approaches.
Javiera Cortés-Ríos, Maria Rodriguez-Fernandez, Peter Karl Sorger, Fabian Fröhlich

PLoS Comput Biol· October 2025

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Hepatitis B In Silico Trials Capture Functional Cure, Indicate Mechanistic Pathways, and Suggest Prognostic Biomarker Signatures.
Javiera Cortés-Ríos, Tianjing Ren, Nathan Hanan, Anna Sher, Ahmed Nader

Clin Pharmacol Ther· September 2025

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Dynamic Modeling of Cell Cycle Arrest Through Integrated Single-Cell and Mathematical Modelling Approaches.
Javiera Cortés-Ríos, Maria Rodriguez-Fernandez, Peter K Sorger, Fabian Fröhlich

bioRxiv· February 2025

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Competitive oxidation of key pentose phosphate pathway enzymes modulates the fate of intermediates and NAPDH production.
Juan Sebastián Reyes, Javiera Cortés-Ríos, Eduardo Fuentes-Lemus, Maria Rodriguez-Fernandez, Michael J Davies

Free Radic Biol Med· September 2024

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Understanding the dosing-time-dependent antihypertensive effect of valsartan and aspirin through mathematical modeling.
Javiera Cortés-Ríos, Maria Rodriguez-Fernandez

Front Endocrinol (Lausanne)· March 2023

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Dosing time optimization of antihypertensive medications by including the circadian rhythm in pharmacokinetic-pharmacodynamic models.
Javiera Cortés-Ríos, Ramón C Hermida, Maria Rodriguez-Fernandez

PLoS Comput Biol· November 2022

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Circadian Rhythm of Blood Pressure of Dipper and Non-dipper Patients With Essential Hypertension: A Mathematical Modeling Approach.
Javiera Cortés-Ríos, Maria Rodriguez-Fernandez

Front Physiol· January 2021

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Protein quantification by bicinchoninic acid (BCA) assay follows complex kinetics and can be performed at short incubation times.
Javiera Cortés-Ríos, Ana María Zárate, Juan David Figueroa, Joaquín Medina, Eduardo Fuentes-Lemus

Anal Biochem· November 2020

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Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching.
Juan David Figueroa, Eduardo Fuentes-Lemus, Eva Dorta, Victoria Melin, Javiera Cortés-Ríos

Redox Biol· June 2019

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