Publications by authors named "Jay Laver"

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Efficacy, immunogenicity, and safety of the live attenuated nasal pertussis vaccine, BPZE1, in the UK: a randomised, placebo-controlled, phase 2b trial using a controlled human infection model with virulent Bordetella pertussis.
Diane Gbesemete, Maheshi N Ramasamy, Muktar Ibrahim, Alison R Hill, Lucy Raud, Jay R Laver

Lancet Microbe· December 2025

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Controlled human infection model of Neisseria lactamica in late pregnancy investigating mother-to-infant transmission in the UK: a single-arm pilot trial.
Anastasia A Theodosiou, Debby Bogaert, David W Cleary, Adam P Dale, Diane F Gbesemete, Jay R Laver

Lancet Microbe· April 2025

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Effect of colonisation with Neisseria lactamica on cross-reactive anti-meningococcal B-cell responses: a randomised, controlled, human infection trial.
Adam P Dale, Anastasia A Theodosiou, Diane F Gbesemete, Jonathan M Guy, Eleanor F Jones, Jay R Laver

Lancet Microbe· December 2022

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Controlled human infection with in late pregnancy to measure horizontal transmission and microbiome changes in mother-neonate pairs: a single-arm interventional pilot study protocol.
Anastasia A Theodosiou, Jay R Laver, Adam P Dale, David W Cleary, Christine E Jones

BMJ Open· May 2022

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Neisseria lactamica Controlled Human Infection Model.
Adam P Dale, Diane F Gbesemete, Robert C Read, Jay R Laver

Methods Mol Biol· December 2021

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A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage.
Jay R Laver, Diane Gbesemete, Adam P Dale, Zoe C Pounce, Carl N Webb

Sci Transl Med· July 2021

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Manipulating the infant respiratory microbiomes to improve clinical outcomes: A review of the literature.
Anastasia A Theodosiou, Robert B Dorey, Jay R Laver, David W Cleary, Robert C Read

J Infect· June 2021

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Erratum: Blume, C., et al. Modulation of Human Airway Barrier Functions during and Infection Running Title: Airway Barrier Functions during Bacterial Infections. 2016, , 53.
Cornelia Blume, Jonathan David, Rachel E Bell, Jay R Laver, Robert C Read

Pathogens· November 2020

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Protocol for a controlled human infection with genetically modified expressing the meningococcal vaccine antigen NadA: a potent new technique for experimental medicine.
Diane Gbesemete, Jay Robert Laver, Hans de Graaf, Muktar Ibrahim, Andrew Vaughan

BMJ Open· May 2019

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Genomes of Escherichia coli bacteraemia isolates originating from urinary tract foci contain more virulence-associated genes than those from non-urinary foci and neutropaenic hosts.
Adam P Dale, Anish K Pandey, Richard J Hesp, Konstantinos Belogiannis, Jay R Laver

J Infect· December 2018

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Microevolution of Neisseria lactamica during nasopharyngeal colonisation induced by controlled human infection.
Anish Pandey, David W Cleary, Jay R Laver, Andrew Gorringe, Alice M Deasy

Nat Commun· November 2018

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Correction to: Y92-1009 complete genome sequence.
Anish K Pandey, David W Cleary, Jay R Laver, Martin C J Maiden, Xavier Didelot

Stand Genomic Sci· February 2018

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D-methionine interferes with non-typeable Haemophilus influenzae peptidoglycan synthesis during growth and biofilm formation.
Harriet Dawe, Evelin Berger, Carina Sihlbom, Elizabeth M Angus, Robert P Howlin, Jay R Laver

Microbiology (Reading)· July 2017

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Y92-1009 complete genome sequence.
Anish K Pandey, David W Cleary, Jay R Laver, Martin C J Maiden, Xavier Didelot

Stand Genomic Sci· July 2017

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Modulation of Human Airway Barrier Functions during Burkholderia thailandensis and Francisella tularensis Infection Running Title: Airway Barrier Functions during Bacterial Infections.
Cornelia Blume, Jonathan David, Rachel E Bell, Jay R Laver, Robert C Read

Pathogens· August 2016

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Neisserial Molecular Adaptations to the Nasopharyngeal Niche.
Jay R Laver, Sara E Hughes, Robert C Read

Adv Microb Physiol· April 2016

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A putative amino acid ABC transporter substrate-binding protein, NMB1612, from Neisseria meningitidis, induces murine bactericidal antibodies against meningococci expressing heterologous NMB1612 proteins.
Miao-Chiu Hung, María Victoria Humbert, Jay R Laver, Renee Phillips, John E Heckels

Vaccine· August 2015

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Nitrosothiols in bacterial pathogens and pathogenesis.
Jay R Laver, Samantha McLean, Lesley A H Bowman, Laura J Harrison, Robert C Read

Antioxid Redox Signal· January 2013

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Bacterial nitric oxide detoxification prevents host cell S-nitrosothiol formation: a novel mechanism of bacterial pathogenesis.
Jay R Laver, Tânia M Stevanin, Sarah L Messenger, Amy Dehn Lunn, Margaret E Lee

FASEB J· January 2010

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Chemiluminescence quantification of NO and its derivatives in liquid samples.
Jay R Laver, Tânia M Stevanin, Robert C Read

Methods Enzymol· May 2008

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Metabolism of nitric oxide by Neisseria meningitidis modifies release of NO-regulated cytokines and chemokines by human macrophages.
Tânia M Stevanin, Jay R Laver, Robert K Poole, James W B Moir, Robert C Read

Microbes Infect· July 2007

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Nitric oxide releases intracellular zinc from prokaryotic metallothionein in Escherichia coli.
Marie R B Binet, Hugo Cruz-Ramos, Jay Laver, Martin N Hughes, Robert K Poole

FEMS Microbiol Lett· July 2002

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