Publications by authors named "Jean Labrecque"

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A combined digital microfluidic test for assessing infection and immunity status for viral disease in saliva.
N Sathishkumar, Jose Gilberto Camacho Valenzuela, Nguyen H Le, Anthony K C Yong, Martin A Rossotti, Jean Labrecque

Lab Chip· June 2025

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Specificity for a CCR5 Inhibitor Is Conferred by a Single Amino Acid Residue: ROLE OF ILE198.
Gloria Lau, Jean Labrecque, Markus Metz, Roy Vaz, Simon P Fricker

J Biol Chem· April 2015

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Discovery of a 4-aryloxy-1H-pyrrolo[3,2-c]pyridine and a 1-aryloxyisoquinoline series of TRPA1 antagonists.
Yun-Jin Hu, Miguel St-Onge, Sébastien Laliberté, Frédéric Vallée, Shujuan Jin, Jean Labrecque

Bioorg Med Chem Lett· July 2014

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Discovery of a series of aryl-N-(3-(alkylamino)-5-(trifluoromethyl)phenyl)benzamides as TRPA1 antagonists.
Sébastien Laliberté, Frédéric Vallée, Pierre-André Fournier, Leanne Bedard, Jean Labrecque

Bioorg Med Chem Lett· July 2014

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RARα-PLZF oncogene inhibits C/EBPα function in myeloid cells.
Nathalie Girard, Mathieu Tremblay, Magali Humbert, Benoît Grondin, André Haman, Jean Labrecque

Proc Natl Acad Sci U S A· August 2013

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Novel methodology to identify TRPV1 antagonists independent of capsaicin activation.
Stephen Zicha, Olivier Radresa, Patricia Laplante, Michael Morton, Karen Jones, Jean Labrecque

J Biomol Screen· June 2013

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Discovery of P2X3 selective antagonists for the treatment of chronic pain.
Louis-David Cantin, Malken Bayrakdarian, Christophe Buon, Eric Grazzini, Yun-Jin Hu, Jean Labrecque

Bioorg Med Chem Lett· April 2012

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The molecular pharmacology of AMD11070: an orally bioavailable CXCR4 HIV entry inhibitor.
Renee M Mosi, Virginia Anastassova, Jennifer Cox, Marilyn C Darkes, Stefan R Idzan, Jean Labrecque

Biochem Pharmacol· February 2012

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Prospective CCR5 small molecule antagonist compound design using a combined mutagenesis/modeling approach.
Markus Metz, Elyse Bourque, Jean Labrecque, Sanjay J Danthi, Jonathan Langille

J Am Chem Soc· October 2011

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HIV-1 entry inhibition by small-molecule CCR5 antagonists: a combined molecular modeling and mutant study using a high-throughput assay.
Jean Labrecque, Markus Metz, Gloria Lau, Marilyn C Darkes, Rebecca S Y Wong

Virology· May 2011

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Design and synthesis of pyridin-2-yloxymethylpiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication.
Renato Skerlj, Gary Bridger, Yuanxi Zhou, Elyse Bourque, Jonathan Langille, Jean Labrecque

Bioorg Med Chem Lett· April 2011

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Pharmacology of AMD3465: a small molecule antagonist of the chemokine receptor CXCR4.
Veronique Bodart, Virginia Anastassov, Marilyn C Darkes, Stefan R Idzan, Jean Labrecque

Biochem Pharmacol· October 2009

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A time-resolved fluorescent lanthanide (Eu)-GTP binding assay for chemokine receptors as targets in drug discovery.
Jean Labrecque, Rebecca S Y Wong, Simon P Fricker

Methods Mol Biol· July 2009

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Comparison of the potential multiple binding modes of bicyclam, monocylam, and noncyclam small-molecule CXC chemokine receptor 4 inhibitors.
Rebecca S Y Wong, Veronique Bodart, Markus Metz, Jean Labrecque, Gary Bridger

Mol Pharmacol· December 2008

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Characterization of the molecular pharmacology of AMD3100: a specific antagonist of the G-protein coupled chemokine receptor, CXCR4.
Simon P Fricker, Virginia Anastassov, Jennifer Cox, Marilyn C Darkes, Ognjen Grujic, Jean Labrecque

Biochem Pharmacol· August 2006

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Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model.
Lauri Burroughs, Marco Mielcarek, Marie-Térèse Little, Gary Bridger, Ron Macfarland, Jean Labrecque

Blood· December 2005

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The development of an europium-GTP assay to quantitate chemokine antagonist interactions for CXCR4 and CCR5.
Jean Labrecque, Virginia Anastassov, Gloria Lau, Marilyn Darkes, Renee Mosi

Assay Drug Dev Technol· December 2005

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Natriuretic peptide receptor A activation stabilizes a membrane-distal dimer interface.
André De Léan, Normand McNicoll, Jean Labrecque

J Biol Chem· March 2003

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Allotopic antagonism of the non-peptide atrial natriuretic peptide (ANP) antagonist HS-142-1 on natriuretic peptide receptor NPR-A.
Hugo Poirier, Jean Labrecque, Julie Deschênes, André DeLéan

Biochem J· February 2002

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