Publications by authors named "Hugo Poirier"

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The Discovery of RP-2119: A Potent, Selective, and Orally Bioavailable Polθ ATPase Inhibitor.
Philippe Mochirian, Robert Papp, Marie-Claude Mathieu, Gino B Ferraro, Evelyne Dietrich, Hugo Poirier

J Med Chem· September 2025

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Identification of , an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.
Monica Bubenik, Pavel Mader, Philippe Mochirian, Fréderic Vallée, Jillian Clark, Hugo Poirier

J Med Chem· October 2022

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A strategy to reduce biliary clearance in early drug discovery.
Nathalie Rioux, Edith Bellavance, Hugo Poirier, Mariève Dupuis, Michel Garneau

J Pharmacol Toxicol Methods· September 2014

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A membrane vesicle-based assay to enable prediction of human biliary excretion.
Federico Colombo, Hugo Poirier, Nathalie Rioux, Maria Arias Montecillo, Jianmin Duan

Xenobiotica· October 2013

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Mercury and flooding cycles in the Tapajós River basin, Brazilian Amazon: the role of periphyton of a floating macrophyte (Paspalum repens).
Sérgio A Coelho-Souza, Jean R D Guimarães, Márcio R Miranda, Hugo Poirier, Jane B N Mauro

Sci Total Environ· June 2011

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Biarylimidazoles as inhibitors of microsomal prostaglandin E2 synthase-1.
Tom Y H Wu, Hélène Juteau, Yves Ducharme, Richard W Friesen, Sébastien Guiral, Hugo Poirier

Bioorg Med Chem Lett· December 2010

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Linking bisphosphonates to the free amino groups in fluoroquinolones: preparation of osteotropic prodrugs for the prevention of osteomyelitis.
Tom J Houghton, Kelly S E Tanaka, Ting Kang, Evelyne Dietrich, Yanick Lafontaine, Hugo Poirier

J Med Chem· November 2008

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Bisphosphonated fluoroquinolone esters as osteotropic prodrugs for the prevention of osteomyelitis.
Kelly S E Tanaka, Tom J Houghton, Ting Kang, Evelyne Dietrich, Daniel Delorme, Hugo Poirier

Bioorg Med Chem· October 2008

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MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis.
Patsy Clark, Steven E Rowland, Danielle Denis, Marie-Claude Mathieu, Rino Stocco, Hugo Poirier

J Pharmacol Exp Ther· May 2008

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Novel non-nucleobase inhibitors of Staphylococcus aureus DNA polymerase IIIC.
Yannick Rose, Stéphane Ciblat, Ranga Reddy, Adam C Belley, Evelyne Dietrich, Hugo Poirier

Bioorg Med Chem Lett· February 2006

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Allotopic antagonism of the non-peptide atrial natriuretic peptide (ANP) antagonist HS-142-1 on natriuretic peptide receptor NPR-A.
Hugo Poirier, Jean Labrecque, Julie Deschênes, André DeLéan

Biochem J· February 2002

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