Publications by authors named "Jean Philippe Stephan"

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Mathematical modeling of the microtubule detyrosination/tyrosination cycle for cell-based drug screening design.
Jeremy Grignard, Véronique Lamamy, Eva Vermersch, Philippe Delagrange, Jean-Philippe Stephan

PLoS Comput Biol· June 2022

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A putative new melatonin binding site in sheep brain, MTx: preliminary observations and characteristics.
Preety Shabajee-Alibay, Anne Bonnaud, Benoit Malpaux, Philippe Delagrange, Valérie Audinot, Jean-Philippe Stephan

J Pharmacol Exp Ther· October 2021

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[From high content screening to target deconvolution: New insights for phenotypic approaches].
Preety Shabajee, Albane Gaudeau, Céline Legros, Thierry Dorval, Jean-Philippe Stéphan

Med Sci (Paris)· March 2021

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Filling the drug discovery gap: is high-content screening the missing link?
Thierry Dorval, Benjamin Chanrion, Marie-Elodie Cattin, Jean Philippe Stephan

Curr Opin Pharmacol· October 2018

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Gene expression profiling during hibernation in the European hamster.
Célia Gautier, Béatrice Bothorel, Dominique Ciocca, Damien Valour, Albane Gaudeau, Jean-Philippe Stephan

Sci Rep· September 2018

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SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer.
Manuel Viotti, Catherine Wilson, Mark McCleland, Hartmut Koeppen, Benjamin Haley, Jean-Philippe Stephan

J Cell Biol· February 2018

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Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure.
Gulfem Dilek Guler, Charles Albert Tindell, Robert Pitti, Catherine Wilson, Katrina Nichols, Jean-Philippe Stephan

Cancer Cell· August 2017

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Proline Starvation Induces Unresolved ER Stress and Hinders mTORC1-Dependent Tumorigenesis.
Nisebita Sahu, Darlene Dela Cruz, Min Gao, Wendy Sandoval, Peter M Haverty, Jean-Philippe Stephan

Cell Metab· November 2016

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Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs.
Nisebita Sahu, Jean-Philippe Stephan, Darlene Dela Cruz, Mark Merchant, Benjamin Haley

Nat Commun· August 2016

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High-throughput drug profiling with voltage- and calcium-sensitive fluorescent probes in human iPSC-derived cardiomyocytes.
Stephane Bedut, Christine Seminatore-Nole, Veronique Lamamy, Sarah Caignard, Jean A Boutin, Jean-Philippe Stephan

Am J Physiol Heart Circ Physiol· July 2016

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Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway.
Sophie Trefely, Poh-Sim Khoo, James R Krycer, Rima Chaudhuri, Daniel J Fazakerley, Jean-Philippe Stephan

J Biol Chem· October 2015

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Membrane display and functional analysis of juxtacrine ligand-receptor signaling.
Pradeep M Nair, Hai Ngu, Eric Torres, Scot Marsters, David A Lawrence, Jean-Philippe Stephan

Biotechniques· October 2015

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Using RNAi screening technologies to interrogate the extrinsic apoptosis pathway.
Jean Philippe Stephan

Methods Enzymol· February 2015

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Defining the ligand specificity of the deleted in colorectal cancer (DCC) receptor.
Patrick C G Haddick, Irene Tom, Elizabeth Luis, Gabriel Quiñones, Bernd J Wranik, Jean-Philippe Stephan

PLoS One· September 2014

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Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition.
Catherine Wilson, Katrina Nicholes, Daisy Bustos, Eva Lin, Qinghua Song, Jean-Philippe Stephan

Oncotarget· September 2014

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An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth.
Adam S Adler, Mark L McCleland, Sharon Yee, Murat Yaylaoglu, Sofia Hussain, Jean-Philippe Stephan

Genes Dev· May 2014

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Identification and analysis of in vivo VEGF downstream markers link VEGF pathway activity with efficacy of anti-VEGF therapies.
Matthew J Brauer, Guanglei Zhuang, Maike Schmidt, Jenny Yao, Xiumin Wu, Jean-Philippe Stephan

Clin Cancer Res· July 2013

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Application of a new wall-less plate technology to complex multistep cell-based investigations using suspension cells.
Gabriel A Quiñones, Travis I Moore, Katrina Nicholes, Hyunjae Lee, Sudong Kim, Jean-Philippe Stephan

Blood· February 2013

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TRAF2 Sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer.
Francois Gonzalvez, David Lawrence, Becky Yang, Sharon Yee, Robert Pitti, Jean-Philippe Stephan

Mol Cell· December 2012

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Production, characterization, and pharmacokinetic properties of antibodies with N-linked mannose-5 glycans.
Marcella Yu, Darren Brown, Chae Reed, Shan Chung, Jeff Lutman, Jean-Philippe Stephan

MAbs· November 2012

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An integrated genomic screen identifies LDHB as an essential gene for triple-negative breast cancer.
Mark L McCleland, Adam S Adler, Yonglei Shang, Thomas Hunsaker, Tom Truong, Jean-Philippe Stephan

Cancer Res· November 2012

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Antibodies against the gH/gL/UL128/UL130/UL131 complex comprise the majority of the anti-cytomegalovirus (anti-CMV) neutralizing antibody response in CMV hyperimmune globulin.
Ashley E Fouts, Pamela Chan, Jean-Philippe Stephan, Richard Vandlen, Becket Feierbach

J Virol· July 2012

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Ultrasensitive detection of cellular protein interactions using bioluminescence resonance energy transfer quantum dot-based nanoprobes.
Gabriel A Quiñones, Steven C Miller, Sukanta Bhattacharyya, Daniel Sobek, Jean-Philippe Stephan

J Cell Biochem· July 2012

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Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).
John A Flygare, Maureen Beresini, Nageshwar Budha, Helen Chan, Iris T Chan, Jean-Philippe Stephan

J Med Chem· May 2012

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Preclinical pharmacokinetics of MFGR1877A, a human monoclonal antibody to FGFR3, and prediction of its efficacious clinical dose for the treatment of t(4;14)-positive multiple myeloma.
Amrita V Kamath, Dan Lu, Priyanka Gupta, Denise Jin, Yan Xin, Jean-Philippe Stephan

Cancer Chemother Pharmacol· April 2012

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